Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts.

Descripción del Articulo

El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.
Detalles Bibliográficos
Autores: Phan, Tung Gia, Sadeghi, Mohammadreza, Altan, Eda, Deng, Xutao, Delwart, Eric, Del Valle Mendoza, Juana Mercedes
Formato: artículo
Fecha de Publicación:2017
Institución:Universidad Peruana de Ciencias Aplicadas
Repositorio:UPC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorioacademico.upc.edu.pe:10757/622325
Enlace del recurso:https://doi.org/10.1007/s11262-017-1514-3
http://hdl.handle.net/10757/622325
Nivel de acceso:acceso abierto
Materia:Dicistrovirus
Fever
Metagenomics
Partitivirus
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dc.title.es.fl_str_mv Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts.
title Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts.
spellingShingle Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts.
Phan, Tung Gia
Dicistrovirus
Fever
Metagenomics
Partitivirus
title_short Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts.
title_full Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts.
title_fullStr Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts.
title_full_unstemmed Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts.
title_sort Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts.
author Phan, Tung Gia
author_facet Phan, Tung Gia
Sadeghi, Mohammadreza
Altan, Eda
Deng, Xutao
Delwart, Eric
Del Valle Mendoza, Juana Mercedes
author_role author
author2 Sadeghi, Mohammadreza
Altan, Eda
Deng, Xutao
Delwart, Eric
Del Valle Mendoza, Juana Mercedes
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Phan, Tung Gia
Sadeghi, Mohammadreza
Altan, Eda
Deng, Xutao
Delwart, Eric
Del Valle Mendoza, Juana Mercedes
dc.subject.es.fl_str_mv Dicistrovirus
Fever
Metagenomics
Partitivirus
topic Dicistrovirus
Fever
Metagenomics
Partitivirus
description El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.
publishDate 2017
dc.date.accessioned.none.fl_str_mv 2017-10-27T19:53:47Z
dc.date.available.none.fl_str_mv 2017-10-27T19:53:47Z
dc.date.issued.fl_str_mv 2017-10-17
dc.type.es.fl_str_mv info:eu-repo/semantics/article
dc.type.version.none.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a901
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dc.identifier.citation.es.fl_str_mv Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts. 2017 Virus Genes
dc.identifier.issn.none.fl_str_mv 1572-994X
dc.identifier.pmid.none.fl_str_mv 29043660
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1007/s11262-017-1514-3
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10757/622325
dc.identifier.journal.es.fl_str_mv Virus genes
identifier_str_mv Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts. 2017 Virus Genes
1572-994X
29043660
Virus genes
url https://doi.org/10.1007/s11262-017-1514-3
http://hdl.handle.net/10757/622325
dc.language.iso.es.fl_str_mv eng
language eng
dc.relation.url.es.fl_str_mv https://www.ncbi.nlm.nih.gov/pubmed/?term=29043660%5Buid%5D
dc.rights.es_PE.fl_str_mv info:eu-repo/semantics/openAccess
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eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0/
dc.format.es.fl_str_mv application/pdf
dc.publisher.es.fl_str_mv Springer International Publishing
dc.source.none.fl_str_mv reponame:UPC-Institucional
instname:Universidad Peruana de Ciencias Aplicadas
instacron:UPC
instname_str Universidad Peruana de Ciencias Aplicadas
instacron_str UPC
institution UPC
reponame_str UPC-Institucional
collection UPC-Institucional
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spelling virtual::429-1Phan, Tung GiaSadeghi, MohammadrezaAltan, EdaDeng, XutaoDelwart, EricDel Valle Mendoza, Juana Mercedes2017-10-27T19:53:47Z2017-10-27T19:53:47Z2017-10-17Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts. 2017 Virus Genes1572-994X29043660https://doi.org/10.1007/s11262-017-1514-3http://hdl.handle.net/10757/622325Virus genesEl texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.Serum samples collected from 88 Peruvians with unexplained fever were analyzed for viral sequences using metagenomics. Nucleic acids of anelloviruses, pegivirus A (GBV-C), HIV, Dengue virus, and Oropouche virus were detected. We also characterized from two sera the RNA genomes of new species of partitivirus and dicistrovirus belonging to viral families known to infect fungi or arthropod, respectively. Genomic DNA of a putative fungal cellular host could be PCR amplified from the partitivirus-containing serum sample. The detection in human serum of nucleic acids from viral families not known to infect vertebrates may indicate contamination during sample collection and aliquoting or human infection by their presumed cellular host, here a fungus. The role, if any, of the non-vertebrate infecting viruses detected in serum in inducing fever is unknown.Revisión por paresapplication/pdfengSpringer International Publishinghttps://www.ncbi.nlm.nih.gov/pubmed/?term=29043660%5Buid%5Dinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/4.0/DicistrovirusFeverMetagenomicsPartitivirusSera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts.info:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a901reponame:UPC-Institucionalinstname:Universidad Peruana de Ciencias Aplicadasinstacron:UPC2018-06-17T05:34:28ZSerum samples collected from 88 Peruvians with unexplained fever were analyzed for viral sequences using metagenomics. Nucleic acids of anelloviruses, pegivirus A (GBV-C), HIV, Dengue virus, and Oropouche virus were detected. We also characterized from two sera the RNA genomes of new species of partitivirus and dicistrovirus belonging to viral families known to infect fungi or arthropod, respectively. Genomic DNA of a putative fungal cellular host could be PCR amplified from the partitivirus-containing serum sample. The detection in human serum of nucleic acids from viral families not known to infect vertebrates may indicate contamination during sample collection and aliquoting or human infection by their presumed cellular host, here a fungus. The role, if any, of the non-vertebrate infecting viruses detected in serum in inducing fever is unknown.Publication2dbf1f9b-54ce-569d-ada7-1cc4589cc28bvirtual::429-12dbf1f9b-54ce-569d-ada7-1cc4589cc28bvirtual::429-1TEXTVirus Genes.pdf.txtVirus Genes.pdf.txtExtracted Texttext/plain1272https://upc.dspace7.openrepository.com/bitstreams/a598f5b9-45ae-5f91-ae92-4c7c3cbb18cb/download9ebeb47b5409211904dd742b566326c6MD53THUMBNAILVirus Genes.pdf.jpgVirus Genes.pdf.jpgGenerated Thumbnailimage/jpeg48330https://upc.dspace7.openrepository.com/bitstreams/108b8b97-098a-5edf-a120-caa7c195288b/download9bd7c5bef36f9766c028613144ade090MD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81702https://upc.dspace7.openrepository.com/bitstreams/c2feadfe-3db8-592e-a3fc-e8dd845bf1df/download255616c2e22876c8a237cd50f1bc22a3MD51ORIGINALVirus Genes.pdfVirus Genes.pdfapplication/pdf93600https://upc.dspace7.openrepository.com/bitstreams/c1ee8c1e-bd68-5e91-8353-be52b177b194/download9b508b7ec2d373355a96d2084dfc7fc6MD5210757/622325oai:upc.dspace7.openrepository.com:10757/6223252026-05-08 06:17:57.737https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessopen.accesshttps://upc.dspace7.openrepository.comRepositorio académico upcrepositorioacademico@upc.edu.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Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts.
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