Antibiotic resistance in Bartonella bacilliformis clinical isolates from an endemic area of Peru

• Autores: Silva-Caso, Wilmer, J. Ruiz, Del Valle Mendoza, Juana, Pons, Maria J
• Formato: artículo
• Fecha de Publicación: 2015
• Institución: Universidad Peruana de Ciencias Aplicadas
• Repositorio: UPC-Institucional
• Lenguaje: inglés
• OAI Identifier: oai:repositorioacademico.upc.edu.pe:10757/579762
• Enlace del recurso: http://hdl.handle.net/10757/579762
• Nivel de acceso: acceso abierto
• Materia: Bartonella bacilliformis; Endemic area; Perú

Bartonella bacilliformis is a facultative, intracellular, aerobic, Gram-negative coccobacillus causing the so-called Carrión's disease, a human infection endemic to specific areas mainly inhabited by low-income communities of Peru but also present in other Andean communities. It is considered a truly neglected tropical disease and is transmitted through the bite of female sandflies of the genus Lutzomyia [1]. Carrión's disease has two different clinical presentations; an initial febrile and haemolytic anaemia phase, known as Oroya fever, which has a mortality rate ranging from 44% to 88% in untreated patients; and a second phase characterised by the development of dermal eruptions known as Peruvian wart [1,2].