Factors predicting incremental administration of antihypertensive boluses during deep brain stimulator placement for Parkinson’s disease

Descripción del Articulo

avitsir@ccf.org
Detalles Bibliográficos
Autores: Rajan, Shobana, Deogaonkar, Milind, Kaw, Roop, Nada, Eman MS, Hernández, Adrian V., Ebrahim, Zeyd, Avitsian, Rafi
Formato: artículo
Fecha de Publicación:2014
Institución:Universidad Peruana de Ciencias Aplicadas
Repositorio:UPC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorioacademico.upc.edu.pe:10757/336286
Enlace del recurso:http://hdl.handle.net/10757/336286
Nivel de acceso:acceso abierto
Materia:Anesthesia
Deep brain stimulation
Dexmedetomidine
Intraoperative hypertension
Neurosurgery
Parkinson’s disease
Propofol
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dc.title.es_PE.fl_str_mv Factors predicting incremental administration of antihypertensive boluses during deep brain stimulator placement for Parkinson’s disease
title Factors predicting incremental administration of antihypertensive boluses during deep brain stimulator placement for Parkinson’s disease
spellingShingle Factors predicting incremental administration of antihypertensive boluses during deep brain stimulator placement for Parkinson’s disease
Rajan, Shobana
Anesthesia
Deep brain stimulation
Dexmedetomidine
Intraoperative hypertension
Neurosurgery
Parkinson’s disease
Propofol
title_short Factors predicting incremental administration of antihypertensive boluses during deep brain stimulator placement for Parkinson’s disease
title_full Factors predicting incremental administration of antihypertensive boluses during deep brain stimulator placement for Parkinson’s disease
title_fullStr Factors predicting incremental administration of antihypertensive boluses during deep brain stimulator placement for Parkinson’s disease
title_full_unstemmed Factors predicting incremental administration of antihypertensive boluses during deep brain stimulator placement for Parkinson’s disease
title_sort Factors predicting incremental administration of antihypertensive boluses during deep brain stimulator placement for Parkinson’s disease
author Rajan, Shobana
author_facet Rajan, Shobana
Deogaonkar, Milind
Kaw, Roop
Nada, Eman MS
Hernández, Adrian V.
Ebrahim, Zeyd
Avitsian, Rafi
author_role author
author2 Deogaonkar, Milind
Kaw, Roop
Nada, Eman MS
Hernández, Adrian V.
Ebrahim, Zeyd
Avitsian, Rafi
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Rajan, Shobana
Deogaonkar, Milind
Kaw, Roop
Nada, Eman MS
Hernández, Adrian V.
Ebrahim, Zeyd
Avitsian, Rafi
dc.subject.es_PE.fl_str_mv Anesthesia
Deep brain stimulation
Dexmedetomidine
Intraoperative hypertension
Neurosurgery
Parkinson’s disease
Propofol
topic Anesthesia
Deep brain stimulation
Dexmedetomidine
Intraoperative hypertension
Neurosurgery
Parkinson’s disease
Propofol
description avitsir@ccf.org
publishDate 2014
dc.date.accessioned.none.fl_str_mv 2014-11-28T18:19:22Z
dc.date.available.none.fl_str_mv 2014-11-28T18:19:22Z
dc.date.issued.fl_str_mv 2014-11-28
dc.type.es_PE.fl_str_mv info:eu-repo/semantics/article
dc.type.other.es_PE.fl_str_mv Articulo científico
format article
dc.identifier.citation.es_PE.fl_str_mv 1. Rajan S, Deogaonkar M, Kaw R, Nada EM, Hernandez AV, Ebrahim Z, et al. Factors predicting incremental administration of antihypertensive boluses during deep brain stimulator placement for Parkinson’s disease. Journal of Clinical Neuroscience. octubre de 2014;21(10):1790-5.
dc.identifier.issn.none.fl_str_mv 0967-5868
dc.identifier.doi.none.fl_str_mv 10.1016/j.jocn.2014.04.005
dc.identifier.uri.es_PE.fl_str_mv http://hdl.handle.net/10757/336286
dc.identifier.journal.es_PE.fl_str_mv Journal of Clinical Neuroscience
identifier_str_mv 1. Rajan S, Deogaonkar M, Kaw R, Nada EM, Hernandez AV, Ebrahim Z, et al. Factors predicting incremental administration of antihypertensive boluses during deep brain stimulator placement for Parkinson’s disease. Journal of Clinical Neuroscience. octubre de 2014;21(10):1790-5.
0967-5868
10.1016/j.jocn.2014.04.005
Journal of Clinical Neuroscience
url http://hdl.handle.net/10757/336286
dc.language.iso.es_PE.fl_str_mv eng
language eng
dc.relation.url.es_PE.fl_str_mv http://www.sciencedirect.com/science/article/pii/S0967586814002136
dc.rights.es_PE.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.es_PE.fl_str_mv application/pdf
dc.publisher.es_PE.fl_str_mv Elsevier B.V.
dc.source.es_PE.fl_str_mv Universidad Peruana de Ciencias Aplicadas (UPC)
Repositorio Académico - UPC
dc.source.none.fl_str_mv reponame:UPC-Institucional
instname:Universidad Peruana de Ciencias Aplicadas
instacron:UPC
instname_str Universidad Peruana de Ciencias Aplicadas
instacron_str UPC
institution UPC
reponame_str UPC-Institucional
collection UPC-Institucional
bitstream.url.fl_str_mv https://repositorioacademico.upc.edu.pe/bitstream/10757/336286/1/AVHernandez%20JClinNeuroscience2014.pdf
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spelling 5cdefe8701ab160ecad7863c51130f3d-1162d393c8e3f99c2f084552f34e6020f-1b07b0b4cb97d9029fcaf89498a114d54-160938be215ddbd93728392205f12c3bc-1df1954be75757918c00849433ed0d14a-18de7be764e215e7317ceefe233027e67-1888f34a7b4e1d6f4a6dcfd2c62e90af8-1Rajan, ShobanaDeogaonkar, MilindKaw, RoopNada, Eman MSHernández, Adrian V.Ebrahim, ZeydAvitsian, Rafi2014-11-28T18:19:22Z2014-11-28T18:19:22Z2014-11-281. Rajan S, Deogaonkar M, Kaw R, Nada EM, Hernandez AV, Ebrahim Z, et al. Factors predicting incremental administration of antihypertensive boluses during deep brain stimulator placement for Parkinson’s disease. Journal of Clinical Neuroscience. octubre de 2014;21(10):1790-5.0967-586810.1016/j.jocn.2014.04.005http://hdl.handle.net/10757/336286Journal of Clinical Neuroscienceavitsir@ccf.orgHypertension is common in deep brain stimulator (DBS) placement predisposing to intracranial hemorrhage. This retrospective review evaluates factors predicting incremental antihypertensive use intraoperatively. Medical records of Parkinson’s disease (PD) patients undergoing DBS procedure between 2008–2011 were reviewed after Institutional Review Board approval. Anesthesia medication, preoperative levodopa dose, age, preoperative use of antihypertensive medications, diabetes mellitus, anxiety, motor part of the Unified Parkinson’s Disease Rating Scale score and PD duration were collected. Univariate and multivariate analysis was done between each patient characteristic and the number of antihypertensive boluses. From the 136 patients included 60 were hypertensive, of whom 32 were on angiotensin converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB), told to hold on the morning of surgery. Antihypertensive medications were given to 130 patients intraoperatively. Age (relative risk [RR] 1.01; 95% confidence interval [CI] 1.00–1.02; p = 0.005), high Joint National Committee (JNC) class (p < 0.0001), diabetes mellitus (RR 1.4; 95%CI 1.2–17; p < 0.0001) and duration of PD >10 years (RR 1.2; 95%CI 1.1–1.3; p = 0.001) were independent predictors for antihypertensive use. No difference was noted in the mean dose of levodopa (p = 0.1) and levodopa equivalent dose (p = 0.4) between the low (I/II) and high severity (III/IV) JNC groups. Addition of dexmedetomidine to propofol did not influence antihypertensive boluses required (p = 0.38). Intraoperative hypertension during DBS surgery is associated with higher age group, hypertensive, diabetic patients and longer duration of PD. Withholding ACEI or ARB is an independent predictor of hypertension requiring more aggressive therapy. Levodopa withdrawal and choice of anesthetic agent is not associated with higher intraoperative antihypertensive medications.Revisión por paresapplication/pdfengElsevier B.V.http://www.sciencedirect.com/science/article/pii/S0967586814002136info:eu-repo/semantics/openAccessUniversidad Peruana de Ciencias Aplicadas (UPC)Repositorio Académico - UPCreponame:UPC-Institucionalinstname:Universidad Peruana de Ciencias Aplicadasinstacron:UPCAnesthesia41b6c797-2e66-46d5-8d60-ff339d31d464600Deep brain stimulation890b9adf-8a91-43e5-9db9-f0f3612d522b600Dexmedetomidinef4a2b936-029c-438d-af16-1aa48cd99dae600Intraoperative hypertensionfe1df986-4923-44cc-8307-a40a237646a4600Neurosurgeryaf7bac9f-9187-40e5-b6a5-098cf715720f600Parkinson’s disease14ab6f07-bb83-49b0-8803-cad4a0ebb32e600Propofol5805b594-416b-4cfc-b27e-114f01a5fd79600Factors predicting incremental administration of antihypertensive boluses during deep brain stimulator placement for Parkinson’s diseaseinfo:eu-repo/semantics/articleArticulo científico2018-06-17T17:00:28ZHypertension is common in deep brain stimulator (DBS) placement predisposing to intracranial hemorrhage. This retrospective review evaluates factors predicting incremental antihypertensive use intraoperatively. Medical records of Parkinson’s disease (PD) patients undergoing DBS procedure between 2008–2011 were reviewed after Institutional Review Board approval. Anesthesia medication, preoperative levodopa dose, age, preoperative use of antihypertensive medications, diabetes mellitus, anxiety, motor part of the Unified Parkinson’s Disease Rating Scale score and PD duration were collected. Univariate and multivariate analysis was done between each patient characteristic and the number of antihypertensive boluses. From the 136 patients included 60 were hypertensive, of whom 32 were on angiotensin converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB), told to hold on the morning of surgery. Antihypertensive medications were given to 130 patients intraoperatively. Age (relative risk [RR] 1.01; 95% confidence interval [CI] 1.00–1.02; p = 0.005), high Joint National Committee (JNC) class (p < 0.0001), diabetes mellitus (RR 1.4; 95%CI 1.2–17; p < 0.0001) and duration of PD >10 years (RR 1.2; 95%CI 1.1–1.3; p = 0.001) were independent predictors for antihypertensive use. No difference was noted in the mean dose of levodopa (p = 0.1) and levodopa equivalent dose (p = 0.4) between the low (I/II) and high severity (III/IV) JNC groups. Addition of dexmedetomidine to propofol did not influence antihypertensive boluses required (p = 0.38). Intraoperative hypertension during DBS surgery is associated with higher age group, hypertensive, diabetic patients and longer duration of PD. Withholding ACEI or ARB is an independent predictor of hypertension requiring more aggressive therapy. 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