Características de los esquemas de tratamiento antineoplásico, utilizados en el servicio de Hematología Pediátrica del Hospital de Alta Complejidad Virgen de la Puerta – EsSalud, periodo junio – diciembre 2016

• Autor: Sandoval Zavaleta, Edwing Jeanpierre
• Formato: tesis de grado
• Fecha de Publicación: 2017
• Institución: Universidad Nacional de Trujillo
• Repositorio: UNITRU-Tesis
• Lenguaje: español
• OAI Identifier: oai:dspace.unitru.edu.pe:20.500.14414/8008
• Enlace del recurso: https://hdl.handle.net/20.500.14414/8008
• Nivel de acceso: acceso abierto
• Materia: Tratamiento antineoplásico, Diluyentes, Esquemas, Estabilidad

The present report of pre-professional practices aims to characterize the antineoplastic treatment regimens used in the Pediatric Hematology Service of the Hospital of High Complexity Virgen de la Puerta - EsSalud, from June to December 2016. For this purpose, Data the main diagnoses of the patients hospitalized in the service, as well as the most used treatment regimens, the diluents used in their reconstitution and the stability of the prepared oncological mixtures. The main diagnoses of the patients were acute lymphoblastic leukemia with 86.96%, acute myeloid leukemia with 8.7% and B-cell lymphoma, with no other specification with 4.31%; Also the most used antineoplastic treatment regimens were asparaginase IV with 14.57%, cytarabine IV with 10.98%, etoposide IV + cytarabine IV with 10.38%, intrathecal triple methotrexate + cytarabine + dexamethasone with 8.78%, cytarabine iv 2v / day With 5.79%, cyclophosphamide IV with 4.19%, vincristine IV + daunorubicin IV + dexrazoxane IV with 3.39%, ifosfamide IV 2v / day with 3.19%, triple intrathectic methotrexate + cytarabine + dexamethasone + iv cytarabine with 2.79% Ifosfamide IV with 2.2%, other 33.73%; The diluent compatible with the most commonly used antineoplastics was 0.9% sodium chloride. Daunorubicin, doxorubicin, etoposide and fluorouracil have a stability of 24 hours at room temperature; Cyclophosphamide, methotrexate, vincristine have a stability of 48 hours at room temperature; While refrigeration stability is as follows: asparaginase 8 hours, cyclophosphamide 21 days, cytarabine 24 hours, leucovorin and rituximab 24 hours, doxorubicin and ifosfamide 48 hours, methotrexate and vincristine 7 days.Key words: Schemes, antineoplastic treatment, diluents, stability