Influencia de la depresión en la adherencia al tratamiento antirretroviral en pacientes con VIH/SIDA del Hospital Regional de Loreto - 2022

• Autor: Trigoso Pacaya, Cinthya Estefita
• Formato: tesis de grado
• Fecha de Publicación: 2023
• Institución: Universidad Nacional De La Amazonía Peruana
• Repositorio: UNAPIquitos-Institucional
• Lenguaje: español
• OAI Identifier: oai:repositorio.unapiquitos.edu.pe:20.500.12737/9270
• Enlace del recurso: https://hdl.handle.net/20.500.12737/9270
• Nivel de acceso: acceso abierto
• Materia: VIH; Cumplimiento y adherencia al tratamiento; Depresión; Terapia antirretroviral altamente activa; https://purl.org/pe-repo/ocde/ford#3.03.03

Objectives: To evaluate the influence of depression on adherence to antiretroviral treatment (ART) in patients at the Regional Hospital of Loreto, Peru (HRL) during 2022. Methods: Observational cross-sectional study with 261 patients with HIV. The PHQ-9 was used to measure depression and the CEAT-HIV to assess adherence to ART. Results: 29.5% (n=77) of patients present strict adherence to treatment, statistically significant associations were found between non-adherence to ART and sociodemographic, clinical and depression characteristics. A 3.3 times higher risk of non-compliance was observed in patients between 19 and 45 years of age; 3.2 times higher risk in heterosexuals; 10.2 times higher risk in rural areas and singles had 2.3 times higher risk than married or cohabiting. Patients with 5 to 10 years of diagnosis were 3.5 times more likely to be nonadherent compared to those 10 years or older; 6.6-fold higher odds of nonadherence with moderate viral load, and alcohol use prior to diagnosis was associated with a 3.3-fold higher odds of treatment nonadherence compared with never-drinkers. Finally, patients with depression had a 24 times greater risk of not adhering to treatment compared to those without depression. Conclusions: This study confirmed that some level of depression is strongly related to non-adherence to ART in HIV HRL patients in 2022.