The Ankle-Arm Index As a Predictive Risk Factor For Peripheral Arterial Disease In Patients With In Patients With Type 2 Diabetes Mellitus

• Autores: Soares Felício, João, Cavalcante Koury, Camila, Abdallah Zahalan, Nathalie, Souza Resende, Fabrício de, Nascimento de Lemos, Manuela, Motta Corrêa Pinto, Rafael Jardim da, Kzan de Souza Neto, Norberto Jorge, Farias de Franco, Isabela Imbelloni, Neres Lunes de Oliveira, Maria Clara, Alcântara, Angélica Leite de, Souza, Ana Carolina Contente Braga de, Costa Dos Santos, Márcia, Marques de Queiroz, Natércia Neves, Costa Farias, Luciana Marques da, Dias da Silva, Danielle, Miléo Felício, Karem, Cunha de Melo, Franciane Trindade, Abrahão Neto, João Felício
• Formato: artículo
• Fecha de Publicación: 2019
• Institución: Universidad Continental
• Repositorio: CONTINENTAL-Institucional
• Lenguaje: inglés
• OAI Identifier: oai:repositorio.continental.edu.pe:20.500.12394/10159
• Enlace del recurso: https://hdl.handle.net/20.500.12394/10159
• Nivel de acceso: acceso abierto
• Materia: Enfermedad arterial periférica; Diabetes mellitus; http://purl.org/pe-repo/ocde/ford#1.02.02

Background: Peripheral arterial disease in patients with type 2 diabetes mellitus is an important risk factor for vascular events. Recommendations about whether ankle-brachial index should be performed differ depending on the source; therefore, it is necessary to re-evaluate the most important risk factors associated with peripheral arterial disease and whether it is useful to perform ankle-brachial index in newly diagnosed and drug-naïve patients with diabetes, independent of age or peripheral arterial disease symptoms. Methods: A total of 711 subjects were divided into groups: group 1, 600 type 2 diabetes mellitus patients, symptomatic or not for peripheral arterial disease; group 2, 61 type 2 diabetes mellitus patients newly diagnosed and drug naïve; and group 3, 50 subjects without diabetes. Ankle-brachial index, medical records and physical examination were performed in all patients, accessing cardiovascular risk factors. Results: Analysing group 1 asymptomatic patient to peripheral arterial disease, we found abnormal ankle-brachial index in 49% (77/156) ⩾50years and 42% (16/38) <50years (p=not significant). Considering drug-naïve patients, a peripheral arterial disease prevalence of 39% (24/61) was found; among these, 48% (13/27) were <50years and 32% (11/34) were ⩾50years (p=not significant). A forward stepwise regression model was developed, with type 2 diabetes mellitus duration (r2=0.12) and sedentary lifestyle (r2=0.14) found as independent variable predictors of severity of peripheral arterial disease, related to ankle-brachial index. Conclusion: We suggest that, in type 2 diabetes mellitus, ankle-brachial index should be measured at diagnosis. In addition, sedentary lifestyle was strongly associated with presence and severity of peripheral arterial disease.