Protective effect of Chuquiraga spinosa lessing associated with simvastatin on N-Nitroso-N-methylurea (NMU)-induced prostate cancer in rats

Descripción del Articulo

Chuquiraga spinosa Lessing (ChS) has shown protective effect on N-Nitroso-N-methylurea (NMU)-induced prostate cancer in rats. Currently, statins are being studied for their pro-apoptotic and antimetastatic effects. The main objective of this research was to determine the protective effect associated...

Descripción completa

Detalles Bibliográficos
Autores: Arroyo-Acevedo, J.L., Rojas-Armas, J.P., Herrera-Calderón, O., Chávez-Asmat, R., Justil-Guerrero, H.J., Aguilar-Carranza, C., Enciso-Roca, E., Tinco-Jayo, J.A., Yuli-Posadas, R.Á., Franco-Quino, C., Chumpitaz-Cerrate, V.
Formato: artículo
Fecha de Publicación:2019
Institución:Universidad Continental
Repositorio:CONTINENTAL-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorio.continental.edu.pe:20.500.12394/7731
Enlace del recurso:https://hdl.handle.net/20.500.12394/7731
Nivel de acceso:acceso abierto
Materia:Cáncer
Enfermedades
id UCON_0b79719ee7db8eb1f7d12b7e0a080128
oai_identifier_str oai:repositorio.continental.edu.pe:20.500.12394/7731
network_acronym_str UCON
network_name_str CONTINENTAL-Institucional
repository_id_str 4517
dc.title.es_ES.fl_str_mv Protective effect of Chuquiraga spinosa lessing associated with simvastatin on N-Nitroso-N-methylurea (NMU)-induced prostate cancer in rats
title Protective effect of Chuquiraga spinosa lessing associated with simvastatin on N-Nitroso-N-methylurea (NMU)-induced prostate cancer in rats
spellingShingle Protective effect of Chuquiraga spinosa lessing associated with simvastatin on N-Nitroso-N-methylurea (NMU)-induced prostate cancer in rats
Arroyo-Acevedo, J.L.
Cáncer
Enfermedades
title_short Protective effect of Chuquiraga spinosa lessing associated with simvastatin on N-Nitroso-N-methylurea (NMU)-induced prostate cancer in rats
title_full Protective effect of Chuquiraga spinosa lessing associated with simvastatin on N-Nitroso-N-methylurea (NMU)-induced prostate cancer in rats
title_fullStr Protective effect of Chuquiraga spinosa lessing associated with simvastatin on N-Nitroso-N-methylurea (NMU)-induced prostate cancer in rats
title_full_unstemmed Protective effect of Chuquiraga spinosa lessing associated with simvastatin on N-Nitroso-N-methylurea (NMU)-induced prostate cancer in rats
title_sort Protective effect of Chuquiraga spinosa lessing associated with simvastatin on N-Nitroso-N-methylurea (NMU)-induced prostate cancer in rats
author Arroyo-Acevedo, J.L.
author_facet Arroyo-Acevedo, J.L.
Rojas-Armas, J.P.
Herrera-Calderón, O.
Chávez-Asmat, R.
Justil-Guerrero, H.J.
Aguilar-Carranza, C.
Enciso-Roca, E.
Tinco-Jayo, J.A.
Yuli-Posadas, R.Á.
Franco-Quino, C.
Chumpitaz-Cerrate, V.
author_role author
author2 Rojas-Armas, J.P.
Herrera-Calderón, O.
Chávez-Asmat, R.
Justil-Guerrero, H.J.
Aguilar-Carranza, C.
Enciso-Roca, E.
Tinco-Jayo, J.A.
Yuli-Posadas, R.Á.
Franco-Quino, C.
Chumpitaz-Cerrate, V.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Arroyo-Acevedo, J.L.
Rojas-Armas, J.P.
Herrera-Calderón, O.
Chávez-Asmat, R.
Justil-Guerrero, H.J.
Aguilar-Carranza, C.
Enciso-Roca, E.
Tinco-Jayo, J.A.
Yuli-Posadas, R.Á.
Franco-Quino, C.
Chumpitaz-Cerrate, V.
dc.subject.es_ES.fl_str_mv Cáncer
Enfermedades
topic Cáncer
Enfermedades
description Chuquiraga spinosa Lessing (ChS) has shown protective effect on N-Nitroso-N-methylurea (NMU)-induced prostate cancer in rats. Currently, statins are being studied for their pro-apoptotic and antimetastatic effects. The main objective of this research was to determine the protective effect associated with the oral administration of simvastatin and ethanolic extract of the aerial parts of ChS in the prevention of prostate cancer.
publishDate 2019
dc.date.accessioned.none.fl_str_mv 2020-07-14T21:00:52Z
dc.date.available.none.fl_str_mv 2020-07-14T21:00:52Z
dc.date.issued.fl_str_mv 2019
dc.type.es_ES.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.citation.es_ES.fl_str_mv Arroyo-Acevedo, J.L., Rojas-Armas, J.P., Herrera-Calderón, O., Chávez-Asmat, R., Justil-Guerrero, H.J., Aguilar-Carranza, C., Enciso-Roca, E., Tinco-Jayo, J.A., Yuli-Posadas, R.Á., Franco-Quino, C. y Chumpitaz-Cerrate, V. (2019). Protective effect of Chuquiraga spinosa lessing associated with simvastatin on N-Nitroso-N-methylurea (NMU)-induced prostate cancer in rats. OncoTargets and Therapy. 12(1). 6555-6562. 10.2147/OTT.S211642
dc.identifier.uri.none.fl_str_mv 10.2147/OTT.S211642
https://hdl.handle.net/20.500.12394/7731
identifier_str_mv Arroyo-Acevedo, J.L., Rojas-Armas, J.P., Herrera-Calderón, O., Chávez-Asmat, R., Justil-Guerrero, H.J., Aguilar-Carranza, C., Enciso-Roca, E., Tinco-Jayo, J.A., Yuli-Posadas, R.Á., Franco-Quino, C. y Chumpitaz-Cerrate, V. (2019). Protective effect of Chuquiraga spinosa lessing associated with simvastatin on N-Nitroso-N-methylurea (NMU)-induced prostate cancer in rats. OncoTargets and Therapy. 12(1). 6555-6562. 10.2147/OTT.S211642
10.2147/OTT.S211642
url https://hdl.handle.net/20.500.12394/7731
dc.language.iso.es_ES.fl_str_mv eng
language eng
dc.relation.es_ES.fl_str_mv https://www.dovepress.com/protective-effect-of-chuquiraga-spinosa-lessing-associated-with-simvas-peer-reviewed-article-OTT#
dc.rights.es_ES.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.accessRights.es_ES.fl_str_mv Acceso abierto
eu_rights_str_mv openAccess
rights_invalid_str_mv Acceso abierto
dc.format.es_ES.fl_str_mv application/pdf
dc.format.extent.es_ES.fl_str_mv P. 6555-6562
dc.publisher.es_ES.fl_str_mv Universidad Continental
dc.source.es_ES.fl_str_mv Universidad Continental
Repositorio Institucional - Continental
dc.source.none.fl_str_mv reponame:CONTINENTAL-Institucional
instname:Universidad Continental
instacron:CONTINENTAL
instname_str Universidad Continental
instacron_str CONTINENTAL
institution CONTINENTAL
reponame_str CONTINENTAL-Institucional
collection CONTINENTAL-Institucional
bitstream.url.fl_str_mv https://repositorio.continental.edu.pe/bitstream/20.500.12394/7731/1/license.txt
bitstream.checksum.fl_str_mv 8a4605be74aa9ea9d79846c1fba20a33
bitstream.checksumAlgorithm.fl_str_mv MD5
repository.name.fl_str_mv Repositorio Continental
repository.mail.fl_str_mv dspaceconti@continental.edu.pe
_version_ 1844107568182460416
spelling Arroyo-Acevedo, J.L.Rojas-Armas, J.P.Herrera-Calderón, O.Chávez-Asmat, R.Justil-Guerrero, H.J.Aguilar-Carranza, C.Enciso-Roca, E.Tinco-Jayo, J.A.Yuli-Posadas, R.Á.Franco-Quino, C.Chumpitaz-Cerrate, V.2020-07-14T21:00:52Z2020-07-14T21:00:52Z2019Arroyo-Acevedo, J.L., Rojas-Armas, J.P., Herrera-Calderón, O., Chávez-Asmat, R., Justil-Guerrero, H.J., Aguilar-Carranza, C., Enciso-Roca, E., Tinco-Jayo, J.A., Yuli-Posadas, R.Á., Franco-Quino, C. y Chumpitaz-Cerrate, V. (2019). Protective effect of Chuquiraga spinosa lessing associated with simvastatin on N-Nitroso-N-methylurea (NMU)-induced prostate cancer in rats. OncoTargets and Therapy. 12(1). 6555-6562. 10.2147/OTT.S21164210.2147/OTT.S211642https://hdl.handle.net/20.500.12394/7731Chuquiraga spinosa Lessing (ChS) has shown protective effect on N-Nitroso-N-methylurea (NMU)-induced prostate cancer in rats. Currently, statins are being studied for their pro-apoptotic and antimetastatic effects. The main objective of this research was to determine the protective effect associated with the oral administration of simvastatin and ethanolic extract of the aerial parts of ChS in the prevention of prostate cancer.application/pdfP. 6555-6562engUniversidad Continentalhttps://www.dovepress.com/protective-effect-of-chuquiraga-spinosa-lessing-associated-with-simvas-peer-reviewed-article-OTT#info:eu-repo/semantics/openAccessAcceso abiertoUniversidad ContinentalRepositorio Institucional - Continentalreponame:CONTINENTAL-Institucionalinstname:Universidad Continentalinstacron:CONTINENTALCáncerEnfermedadesProtective effect of Chuquiraga spinosa lessing associated with simvastatin on N-Nitroso-N-methylurea (NMU)-induced prostate cancer in ratsinfo:eu-repo/semantics/articleLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.continental.edu.pe/bitstream/20.500.12394/7731/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5120.500.12394/7731oai:repositorio.continental.edu.pe:20.500.12394/77312020-07-14 16:00:52.978Repositorio Continentaldspaceconti@continental.edu.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
score 13.378782
Protective effect of Chuquiraga spinosa lessing associated with simvastatin on N-Nitroso-N-methylurea (NMU)-induced prostate cancer in rats
Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).

Ejemplares Similares