The Impact of Human T-Lymphotrophic Virus Type I/II Infection on the Prognosis of Sexually Acquired Cases of Acquired Immunodeficiency Syndrome

• Autores: Gotuzzo Herencia, José Eduardo, Escamilla, J., Phillips, I.A., Sanchez, Jorge, Wignall, F.S., Antigoni, J.
• Formato: artículo
• Fecha de Publicación: 1992
• Institución: Universidad Peruana Cayetano Heredia
• Repositorio: UPCH-Institucional
• Lenguaje: inglés
• OAI Identifier: oai:repositorio.upch.edu.pe:20.500.12866/19028
• Enlace del recurso: https://hdl.handle.net/20.500.12866/19028; https://doi.org/10.1001/archinte.1992.00400190063012
• Nivel de acceso: acceso abierto
• Materia: Acquired Immunodeficiency Syndrome; HIV Seropositivity; Human T-lymphotropic virus 1; Human T-lymphotropic virus 2; mortality; Peru; sexual transmission; https://purl.org/pe-repo/ocde/ford#3.03.08

Twenty (18%) of 111 Peruvian men with sexually acquired human immunodeficiency virus infection were found also to be infected with human T-lymphotrophic virus type I or II in a retrospective study. At the time of data evaluation, 75 patients had reached Centers for Disease Control stage IV (clinical acquired immunodeficiency syndrome) and had not received antiviral medication; mortality in this group was 63.3% (38/60) among patients infected with human immunodeficiency virus alone and 80% (12/15) in the dually infected group. Of the 50 patients who had died, survival time from onset of stage IV to death was shorter in the dually infected group (5.02±3.27 months) than in those with human immunodeficiency virus infection alone (10.07±4.42 months). In Peru, sexually acquired human immunodeficiency virus infection in men is often accompanied by human T-lymphotrophic virus type I/II infection, and dual retrovirus infection is associated with a shorter survival after onset of clinical acquired immunodeficiency syndrome.