Platelet / spleen ratio for the diagnosis of esophageal varices and the risk of bleeding in patients with liver failure: Cociente plaquetas/bazo para el diagnóstico de várices esofágicas y riesgo de sangrado en pacientes con insuficiencia hepática

• Autores: Montiel Jarquín, Álvaro José, Garcia Galicia, Arturo, Gámez Herrera, Andrés, Ixchel González Bravo, Emma, Parker Bosquez, Ricardo Adolfo, Leon Zamudio, José Alfredo, Parra Salazar, José Álvaro, Romero Figueroa, María del Socorro
• Formato: artículo
• Fecha de Publicación: 2021
• Institución: Universidad Ricardo Palma
• Repositorio: Revistas - Universidad Ricardo Palma
• Lenguaje: español; inglés
• OAI Identifier: oai:oai.revistas.urp.edu.pe:article/3708
• Enlace del recurso: http://revistas.urp.edu.pe/index.php/RFMH/article/view/3708
• Nivel de acceso: acceso abierto
• Materia: Varices Esofágicas; Hemorragia Gastrointestinal; Fallo Hepático; Bazo; Plaquetas; Cociente Plaquetas/Diámetro Mayor del Bazo; Insuficiencia Hepática; Esophageal varices; Gastrointestinal bleeding; Hepatic failure; Spleen; Platelets; Platelets/Spleen Major Diameter Ratio

Introduction: Upper gastrointestinal bleeding of variceal origin has a high mortality. The platelet count/spleen major diameter ratio may be a useful noninvasive parameter to predict esophageal variceal bleeding in cirrhotic patients. Objective: to determine the sensitivity and specificity of the platelet count/spleen diameter ratio for the diagnosis of esophageal varices with risk of bleeding in patients with hepatic insufficiency. Material and Methods: Process study, performed in a Second Level Medical Facility, in patients with liver failure who underwent ultrasound, blood cytometry, liver function tests and endoscopy. Sensitivity and specificity of the platelet/spleen ratio were assessed in patients with esophageal variceal and bleeding risk. Results: There were 70 patients: 28 women, 42 men; main cause of liver failure in men was ethylism in 31 patients and hepatitis C virus in 20 women. The spleen-platelet ratio has a sensitivity of 90%, specificity 83%, false positives 16%, false negatives 9%, positive predictive value 94%, negative predictive value 75%, prevalence of 74% and diagnostic accuracy of 88% to diagnose esophageal varices with risk of bleeding. Conclusion: Platelet/spleen ratio is a useful, non-invasive study to diagnose esophageal varices with bleeding risk, in hospitals where endoscopy is not available.