Propylthiouracil induced ANCA positive vasculitis. A case report

• Autores: Soto Fonseca, Marco Antonio, Medina Ramírez, Katherine Fernanda, Sánchez Barjún, Karen
• Formato: artículo
• Fecha de Publicación: 2021
• Institución: Universidad Peruana Cayetano Heredia
• Repositorio: Revistas - Universidad Peruana Cayetano Heredia
• Lenguaje: español
• OAI Identifier: oai:revistas.upch.edu.pe:article/3983
• Enlace del recurso: https://revistas.upch.edu.pe/index.php/RMH/article/view/3983
• Nivel de acceso: acceso abierto

ANCA vasculitis associated to propylthiouracil (PTU) is a rare condition with an incidence of 0.47-0.71 cases per 100,000 patients. It affects mainly minor caliber blood vessels. The skin, kidneys and lungs are the organs most affected. To make the diagnosis it is necessary to have a high index of suspicion and rely on histopathologic findings of skin lesions plus a positive ANCA test. Stopping the inducing drug is usually necessary to manage this condition. We report the case of a 45-year-old woman who consumed PTU for two years for the treatment of hyperthyroidism presenting with painful purpuric plaques in the lower limbs.