In vitro uptake of labeled triiodothyronine I-131 ion exchange resin as a thyroid function test

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The triiodothyronine uptake test, was performed on 44 patients suffering from a variety of thyroid diseases plus 11 pregnant women, using this hormone labeled with I-131 and ionic exchange resin. Among the 44 patients there were 20 with thyrotoxicosis, 10 hypothyroid, 8 with diffuse non-toxic goiter...

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Autor: Pajuelo E., Alfonso
Formato: artículo
Fecha de Publicación:1968
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Lenguaje:español
OAI Identifier:oai:ojs.csi.unmsm:article/5274
Enlace del recurso:https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/5274
Nivel de acceso:acceso abierto
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spelling In vitro uptake of labeled triiodothyronine I-131 ion exchange resin as a thyroid function testCaptación in vitro de la Triyodotironina marcada con I-131 por resina de intercambio iónico como prueba de función tiroideaPajuelo E., AlfonsoThe triiodothyronine uptake test, was performed on 44 patients suffering from a variety of thyroid diseases plus 11 pregnant women, using this hormone labeled with I-131 and ionic exchange resin. Among the 44 patients there were 20 with thyrotoxicosis, 10 hypothyroid, 8 with diffuse non-toxic goiter and 6 with other thyroid conditions with no evidence of thyroid disfunction. An averange of 48,9% uptake for the hyperthyroid, 22,2% for the hypothyroid an 23,3% for the pregnant women was found. This gave a very significant difference from the normal group that averaged 32% according to a previous report. There was no difference between the normal group and the other two groups having no functional disturbance. Our results agree with the findingsof the other investigators in other countries. We think that this is a useful test adding a new parameter for the study of thyroid function. It is no necessary to administer radioactivity to the patient which is advantageous, and it is not modified by small doses of iodine compounds.Se ha efectuado la prueba de captación de la triyodotironina marcada con I-131 por resina de intercambio iónico en 44 pacientes portadores de afecciones tiroideas y 11 mujeres gestantes. De los 44 pacientes, 20 fueron tirotóxicos, 10 hipotiroideos, 8 con bocio difuso no tóxico y 6 con otras afecciones tiroideas sin trastorno funcional evidente. Se ha hallado un promedio de 48,9% de captación por la resina para los hipertiroideos, 22.2% para los hipotiroideos y 23.3% para las gestantes, lo que da una diferencia significativa con los normales, que presentaron un promedio de 32% según un trabajo previo. No hubo diferencia significativa entre los normales y los otros dos grupos sin alteración funcional. Los resultados concuerdan con los hallados en otros países por otros investigadores. Es una pruebe útil que añade un parámetro más al estudio funcional tiroideo y, al no administrar radiactividad al paciente y no ser alterado por pequeñas dosis de compuestos yodados, es de importancia práctica en ciertos casos.Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana1968-06-17info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/527410.15381/anales.v51i1-2.5274Anales de la Facultad de Medicina; Vol. 51 No. 1-2 (1968); 32-40Anales de la Facultad de Medicina; Vol. 51 Núm. 1-2 (1968); 32-401609-94191025-5583reponame:Revistas - Universidad Nacional Mayor de San Marcosinstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMspahttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/5274/4348Derechos de autor 1968 Alfonso Pajuelo E.https://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessoai:ojs.csi.unmsm:article/52742020-04-11T19:20:46Z
dc.title.none.fl_str_mv In vitro uptake of labeled triiodothyronine I-131 ion exchange resin as a thyroid function test
Captación in vitro de la Triyodotironina marcada con I-131 por resina de intercambio iónico como prueba de función tiroidea
title In vitro uptake of labeled triiodothyronine I-131 ion exchange resin as a thyroid function test
spellingShingle In vitro uptake of labeled triiodothyronine I-131 ion exchange resin as a thyroid function test
Pajuelo E., Alfonso
title_short In vitro uptake of labeled triiodothyronine I-131 ion exchange resin as a thyroid function test
title_full In vitro uptake of labeled triiodothyronine I-131 ion exchange resin as a thyroid function test
title_fullStr In vitro uptake of labeled triiodothyronine I-131 ion exchange resin as a thyroid function test
title_full_unstemmed In vitro uptake of labeled triiodothyronine I-131 ion exchange resin as a thyroid function test
title_sort In vitro uptake of labeled triiodothyronine I-131 ion exchange resin as a thyroid function test
dc.creator.none.fl_str_mv Pajuelo E., Alfonso
author Pajuelo E., Alfonso
author_facet Pajuelo E., Alfonso
author_role author
description The triiodothyronine uptake test, was performed on 44 patients suffering from a variety of thyroid diseases plus 11 pregnant women, using this hormone labeled with I-131 and ionic exchange resin. Among the 44 patients there were 20 with thyrotoxicosis, 10 hypothyroid, 8 with diffuse non-toxic goiter and 6 with other thyroid conditions with no evidence of thyroid disfunction. An averange of 48,9% uptake for the hyperthyroid, 22,2% for the hypothyroid an 23,3% for the pregnant women was found. This gave a very significant difference from the normal group that averaged 32% according to a previous report. There was no difference between the normal group and the other two groups having no functional disturbance. Our results agree with the findingsof the other investigators in other countries. We think that this is a useful test adding a new parameter for the study of thyroid function. It is no necessary to administer radioactivity to the patient which is advantageous, and it is not modified by small doses of iodine compounds.
publishDate 1968
dc.date.none.fl_str_mv 1968-06-17
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/5274
10.15381/anales.v51i1-2.5274
url https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/5274
identifier_str_mv 10.15381/anales.v51i1-2.5274
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/5274/4348
dc.rights.none.fl_str_mv Derechos de autor 1968 Alfonso Pajuelo E.
https://creativecommons.org/licenses/by-nc-sa/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Derechos de autor 1968 Alfonso Pajuelo E.
https://creativecommons.org/licenses/by-nc-sa/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana
publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana
dc.source.none.fl_str_mv Anales de la Facultad de Medicina; Vol. 51 No. 1-2 (1968); 32-40
Anales de la Facultad de Medicina; Vol. 51 Núm. 1-2 (1968); 32-40
1609-9419
1025-5583
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reponame_str Revistas - Universidad Nacional Mayor de San Marcos
collection Revistas - Universidad Nacional Mayor de San Marcos
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