Resistance acquired to third generation tyrosine kinase inhibitors in non small cell lung cancer

Descripción del Articulo

Resistance to third-generation tyrosine kinase inhibitors (TKI) is an increasingly frequent event in clinical practice; however, the exact mechanisms by which tumor cells develop such resistance allowing their survival are unknown. A case of resistance to osimertinib (AZD9291) in non small cell lung...

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Detalles Bibliográficos
Autores: Runciman Gozzer, Thanya, Carracedo Gonzáles, Carlos
Formato: artículo
Fecha de Publicación:2018
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Lenguaje:español
OAI Identifier:oai:ojs.csi.unmsm:article/15639
Enlace del recurso:https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/15639
Nivel de acceso:acceso abierto
Materia:Drug Resistance
Tyrosine
Lung Neoplasms
Resistencia a medicamentos
Tirosina
Neoplasia Pulmonar
Descripción
Sumario:Resistance to third-generation tyrosine kinase inhibitors (TKI) is an increasingly frequent event in clinical practice; however, the exact mechanisms by which tumor cells develop such resistance allowing their survival are unknown. A case of resistance to osimertinib (AZD9291) in non small cell lung cancer, evidenced by next generation sequencing (NGS) and its possible therapeutic approach is described.
Resistance acquired to third generation tyrosine kinase inhibitors in non small cell lung cancer
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