Actividad analgésica del extracto acuoso liofilizado de las hojas de Bixa orellana L. en ratones albinos

• Autores: Betancourt B., José, Gorriti, Arilmí, Córdova, Augusta, Ríos, Felipe, Rios, Deysi, Flores, Glendi, Guzman, María, López, Doris, Cruz, Armando
• Formato: artículo
• Fecha de Publicación: 2006
• Institución: Universidad Nacional Mayor de San Marcos
• Repositorio: Revistas - Universidad Nacional Mayor de San Marcos
• Lenguaje: español
• OAI Identifier: oai:ojs.csi.unmsm:article/5954
• Enlace del recurso: https://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/5954
• Nivel de acceso: acceso abierto
• Materia: Pain; analgesic; hot - plate; abdominals contortions; Bixa orellana L.; Dolor; analgesia; Hot-plate; contorsiones abdominales

An experimental research is carried out ain to evaluate the analgesic effect of the lyophilized extract from the Bíxa orellana L leaves, that was administrated by oral via at a 100 and 150 mgkg-l doses. Hot- plate and abdominal contortions methods were applied in the research development. The selected animals were albino male mice from the stock Batb/c-53 at a corporal weight steemed in 23.67 + 1.03g. Paracetamol and indometacina were employed as positive controls at a 400 mgkg-l and 10 mgkg-l doses respectively.According to the obtained results, it concludes that the Bixa orellana L., presents analgesical activity at a peripheric level in the abdominal contortions model, that was directly proportional to the doses under our experimental conditions. .