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New oral anticoagulants in thromboembolism prevention in nonvalvular atrial fibrillation

Descripción del Articulo

Atrial fibrillation is the most frequent cardiac arrhythmia in clinical practice. The value of anticoagulation with vitamin K antagonists like warfarin in the prevention of embolic phenomena is widely demonstrated but managing is difficult because of its known interactions with other drugs and even...

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Detalles Bibliográficos
Autor: Sosa Rosado, José Manuel
Formato: artículo
Fecha de Publicación:2013
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Lenguaje:español
OAI Identifier:oai:ojs.csi.unmsm:article/2391
Enlace del recurso:https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/2391
Nivel de acceso:acceso abierto
Materia:Fibrilación auricular
warfarina
inhibidores directos de la trombina
inhibidores directos del factor Xa.
Atrial fibrillation
warfarin
direct thrombin inhibitors
direct factor Xa inhibitors.
Descripción
Sumario:Atrial fibrillation is the most frequent cardiac arrhythmia in clinical practice. The value of anticoagulation with vitamin K antagonists like warfarin in the prevention of embolic phenomena is widely demonstrated but managing is difficult because of its known interactions with other drugs and even food. Looking for the ideal anticoagulant in the last years new antithrombotic agents have appeared and others are in advanced phases of investigation. In the current review results of new anticoagulant agents development and expectations, opportunities and challenges are described in regards to direct thrombin and Xa factor inhibitors.
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