Usefulness of lithium carbonate, inorganic iodine and plasmapheresis in a patient with severe hyperthyroidism and agranulocytosis due to thiamazole in times of COVID-19

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A 43-year-old woman with a recent diagnosis of Graves-Basedow disease was admitted to the emergency room due to soft tissue infection, thiamazole agranulocytosis, and severe hyperthyroidism. The patient required definitive treatment for hyperthyroidism, but given the context of the...

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Detalles Bibliográficos
Autores: García-Ruiz, Víctor Raúl, Alvarez-Gamero, Julio César, Quinto-Reyes, Fernando, Churampi-López, María Pilar, Paz-Ibarra, José Luis
Formato: artículo
Fecha de Publicación:2020
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Lenguaje:español
OAI Identifier:oai:ojs.csi.unmsm:article/19442
Enlace del recurso:https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/19442
Nivel de acceso:acceso abierto
Materia:Agranulocitosis
Metimazol
Hipertiroidismo
COVID-19
Agranulocytosis
Methimazole
Hyperthyroidism
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spelling Usefulness of lithium carbonate, inorganic iodine and plasmapheresis in a patient with severe hyperthyroidism and agranulocytosis due to thiamazole in times of COVID-19Utilidad del carbonato de litio, yodo inorgánico y plasmaféresis en una paciente con hipertiroidismo severo y agranulocitosis por tiamazol en tiempos de COVID-19García-Ruiz, Víctor RaúlAlvarez-Gamero, Julio CésarQuinto-Reyes, FernandoChurampi-López, María PilarPaz-Ibarra, José LuisAgranulocitosisMetimazolHipertiroidismoCOVID-19AgranulocytosisMethimazoleHyperthyroidismCOVID-19A 43-year-old woman with a recent diagnosis of Graves-Basedow disease was admitted to the emergency room due to soft tissue infection, thiamazole agranulocytosis, and severe hyperthyroidism. The patient required definitive treatment for hyperthyroidism, but given the context of the SARS-COV-2 pandemic, radioactive iodine was not available, so she prepared for total thyroidectomy. A rapid and effective preoperative preparation was required, so it was decided to compensate her hyperthyroidism with lugol, lithium carbonate, dexamethasone and finally plasmapheresis before surgery. Thyroid hormone levels normalized in a short time, and the thyroidectomy was performed. The case is presented because of the anecdotal and because knowledge of management in scenarios, such as this pandemic, where thereis no access to 131I.Mujer de 43 años con diagnóstico reciente de enfermedad de Graves Basedow ingresa a urgencias por infección de tejidos blandos, agranulocitosis por tiamazol e hipertiroidismo descompensado. La paciente requería tratamiento definitivo para hipertiroidismo, pero dado el contexto de la pandemia por SARS-COV-2 no se contaba con yodo radioactivo (131I) por lo que se planteó la tiroidectomía total. Se necesitaba una preparación preoperatoria rápida y eficaz por lo que se decidió compensar su hipertiroidismo con lugol, carbonato de litio, dexametasona y finalmente plasmaféresis antes de cirugía. Con ello se logró disminuir los niveles de hormonas tiroideas en el tiempo deseado y se procedió al tratamiento quirúrgico definitivo. Se presenta el caso por lo anecdótico y por ser necesario el conocimiento del manejo en escenarios, como esta pandemia, donde no haya acceso a 131I.Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana2020-09-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/1944210.15381/anales.v81i3.19442Anales de la Facultad de Medicina; Vol. 81 No. 3 (2020)Anales de la Facultad de Medicina; Vol. 81 Núm. 3 (2020)1609-94191025-5583reponame:Revistas - Universidad Nacional Mayor de San Marcosinstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMspahttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/19442/16289Derechos de autor 2020 Anales de la Facultad de Medicinahttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessoai:ojs.csi.unmsm:article/194422021-02-18T11:08:51Z
dc.title.none.fl_str_mv Usefulness of lithium carbonate, inorganic iodine and plasmapheresis in a patient with severe hyperthyroidism and agranulocytosis due to thiamazole in times of COVID-19
Utilidad del carbonato de litio, yodo inorgánico y plasmaféresis en una paciente con hipertiroidismo severo y agranulocitosis por tiamazol en tiempos de COVID-19
title Usefulness of lithium carbonate, inorganic iodine and plasmapheresis in a patient with severe hyperthyroidism and agranulocytosis due to thiamazole in times of COVID-19
spellingShingle Usefulness of lithium carbonate, inorganic iodine and plasmapheresis in a patient with severe hyperthyroidism and agranulocytosis due to thiamazole in times of COVID-19
García-Ruiz, Víctor Raúl
Agranulocitosis
Metimazol
Hipertiroidismo
COVID-19
Agranulocytosis
Methimazole
Hyperthyroidism
COVID-19
title_short Usefulness of lithium carbonate, inorganic iodine and plasmapheresis in a patient with severe hyperthyroidism and agranulocytosis due to thiamazole in times of COVID-19
title_full Usefulness of lithium carbonate, inorganic iodine and plasmapheresis in a patient with severe hyperthyroidism and agranulocytosis due to thiamazole in times of COVID-19
title_fullStr Usefulness of lithium carbonate, inorganic iodine and plasmapheresis in a patient with severe hyperthyroidism and agranulocytosis due to thiamazole in times of COVID-19
title_full_unstemmed Usefulness of lithium carbonate, inorganic iodine and plasmapheresis in a patient with severe hyperthyroidism and agranulocytosis due to thiamazole in times of COVID-19
title_sort Usefulness of lithium carbonate, inorganic iodine and plasmapheresis in a patient with severe hyperthyroidism and agranulocytosis due to thiamazole in times of COVID-19
dc.creator.none.fl_str_mv García-Ruiz, Víctor Raúl
Alvarez-Gamero, Julio César
Quinto-Reyes, Fernando
Churampi-López, María Pilar
Paz-Ibarra, José Luis
author García-Ruiz, Víctor Raúl
author_facet García-Ruiz, Víctor Raúl
Alvarez-Gamero, Julio César
Quinto-Reyes, Fernando
Churampi-López, María Pilar
Paz-Ibarra, José Luis
author_role author
author2 Alvarez-Gamero, Julio César
Quinto-Reyes, Fernando
Churampi-López, María Pilar
Paz-Ibarra, José Luis
author2_role author
author
author
author
dc.subject.none.fl_str_mv Agranulocitosis
Metimazol
Hipertiroidismo
COVID-19
Agranulocytosis
Methimazole
Hyperthyroidism
COVID-19
topic Agranulocitosis
Metimazol
Hipertiroidismo
COVID-19
Agranulocytosis
Methimazole
Hyperthyroidism
COVID-19
description A 43-year-old woman with a recent diagnosis of Graves-Basedow disease was admitted to the emergency room due to soft tissue infection, thiamazole agranulocytosis, and severe hyperthyroidism. The patient required definitive treatment for hyperthyroidism, but given the context of the SARS-COV-2 pandemic, radioactive iodine was not available, so she prepared for total thyroidectomy. A rapid and effective preoperative preparation was required, so it was decided to compensate her hyperthyroidism with lugol, lithium carbonate, dexamethasone and finally plasmapheresis before surgery. Thyroid hormone levels normalized in a short time, and the thyroidectomy was performed. The case is presented because of the anecdotal and because knowledge of management in scenarios, such as this pandemic, where thereis no access to 131I.
publishDate 2020
dc.date.none.fl_str_mv 2020-09-30
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/19442
10.15381/anales.v81i3.19442
url https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/19442
identifier_str_mv 10.15381/anales.v81i3.19442
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/19442/16289
dc.rights.none.fl_str_mv Derechos de autor 2020 Anales de la Facultad de Medicina
https://creativecommons.org/licenses/by-nc-sa/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Derechos de autor 2020 Anales de la Facultad de Medicina
https://creativecommons.org/licenses/by-nc-sa/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana
publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana
dc.source.none.fl_str_mv Anales de la Facultad de Medicina; Vol. 81 No. 3 (2020)
Anales de la Facultad de Medicina; Vol. 81 Núm. 3 (2020)
1609-9419
1025-5583
reponame:Revistas - Universidad Nacional Mayor de San Marcos
instname:Universidad Nacional Mayor de San Marcos
instacron:UNMSM
instname_str Universidad Nacional Mayor de San Marcos
instacron_str UNMSM
institution UNMSM
reponame_str Revistas - Universidad Nacional Mayor de San Marcos
collection Revistas - Universidad Nacional Mayor de San Marcos
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 13.936249
Usefulness of lithium carbonate, inorganic iodine and plasmapheresis in a patient with severe hyperthyroidism and agranulocytosis due to thiamazole in times of COVID-19
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