Constitutional hepatic dysfunction (Gilbert's disease), about eleven cases studied in the Hospital Obrero de Lima

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We report eleven cases of Constitutional Hepatic dysfunction (Gilbert's disease), studied at the Department of Gastroenterology of the Hospital Obrero de Lima. We place this disease in the group of non Chronicles Hemolytic jaundice due to congenital defects in bilirubin metabolism. It is noted,...

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Detalles Bibliográficos
Autor: León Navarro, Oswaldo
Formato: artículo
Fecha de Publicación:1962
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Lenguaje:español
OAI Identifier:oai:ojs.csi.unmsm:article/6060
Enlace del recurso:https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/6060
Nivel de acceso:acceso abierto
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spelling Constitutional hepatic dysfunction (Gilbert's disease), about eleven cases studied in the Hospital Obrero de LimaDisfunción hepática constitucional (enfermedad de Gilbert), a propósito de once casos estudiados en el Hospital Obrero de Lima.León Navarro, OswaldoWe report eleven cases of Constitutional Hepatic dysfunction (Gilbert's disease), studied at the Department of Gastroenterology of the Hospital Obrero de Lima. We place this disease in the group of non Chronicles Hemolytic jaundice due to congenital defects in bilirubin metabolism. It is noted, according to the new concepts of bilirubin metabolism, the pathogenic mechanism of this disease is related to deficient activity of glucuronyltransferase, the enzyme responsible for bilirubin conjugation with glucuronic acid.Presentamos once casos de Disfunción Hepática Constitucional (Enfermedad de Gilbert), estudiados en el Servicio de Gastroenterología del Hospital Obrero de Lima. Ubicamos esta enfermedad dentro del grupo de las Ictericias Crónicas no Hemolíticas por defectos congénitos en el metabolismo de la bilirrubina. Se señala, de acuerdo con los nuevos conceptos sobre el metabolismo de la bilirrubina, que el mecanismo patogénico de esta enfermedad está en relación con una deficiente actividad de la glucoroniltransferasa, enzima encargada de la conjugación de la bilirrubina con el ácido glucorónico.Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana1962-12-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/606010.15381/anales.v45i3-4.6060Anales de la Facultad de Medicina; Vol. 45 No. 3-4 (1962); 378-396Anales de la Facultad de Medicina; Vol. 45 Núm. 3-4 (1962); 378-3961609-94191025-5583reponame:Revistas - Universidad Nacional Mayor de San Marcosinstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMspahttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/6060/5251Derechos de autor 1962 Oswaldo León Navarrohttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessoai:ojs.csi.unmsm:article/60602020-04-10T13:05:29Z
dc.title.none.fl_str_mv Constitutional hepatic dysfunction (Gilbert's disease), about eleven cases studied in the Hospital Obrero de Lima
Disfunción hepática constitucional (enfermedad de Gilbert), a propósito de once casos estudiados en el Hospital Obrero de Lima.
title Constitutional hepatic dysfunction (Gilbert's disease), about eleven cases studied in the Hospital Obrero de Lima
spellingShingle Constitutional hepatic dysfunction (Gilbert's disease), about eleven cases studied in the Hospital Obrero de Lima
León Navarro, Oswaldo
title_short Constitutional hepatic dysfunction (Gilbert's disease), about eleven cases studied in the Hospital Obrero de Lima
title_full Constitutional hepatic dysfunction (Gilbert's disease), about eleven cases studied in the Hospital Obrero de Lima
title_fullStr Constitutional hepatic dysfunction (Gilbert's disease), about eleven cases studied in the Hospital Obrero de Lima
title_full_unstemmed Constitutional hepatic dysfunction (Gilbert's disease), about eleven cases studied in the Hospital Obrero de Lima
title_sort Constitutional hepatic dysfunction (Gilbert's disease), about eleven cases studied in the Hospital Obrero de Lima
dc.creator.none.fl_str_mv León Navarro, Oswaldo
author León Navarro, Oswaldo
author_facet León Navarro, Oswaldo
author_role author
description We report eleven cases of Constitutional Hepatic dysfunction (Gilbert's disease), studied at the Department of Gastroenterology of the Hospital Obrero de Lima. We place this disease in the group of non Chronicles Hemolytic jaundice due to congenital defects in bilirubin metabolism. It is noted, according to the new concepts of bilirubin metabolism, the pathogenic mechanism of this disease is related to deficient activity of glucuronyltransferase, the enzyme responsible for bilirubin conjugation with glucuronic acid.
publishDate 1962
dc.date.none.fl_str_mv 1962-12-31
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/6060
10.15381/anales.v45i3-4.6060
url https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/6060
identifier_str_mv 10.15381/anales.v45i3-4.6060
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/6060/5251
dc.rights.none.fl_str_mv Derechos de autor 1962 Oswaldo León Navarro
https://creativecommons.org/licenses/by-nc-sa/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Derechos de autor 1962 Oswaldo León Navarro
https://creativecommons.org/licenses/by-nc-sa/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana
publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana
dc.source.none.fl_str_mv Anales de la Facultad de Medicina; Vol. 45 No. 3-4 (1962); 378-396
Anales de la Facultad de Medicina; Vol. 45 Núm. 3-4 (1962); 378-396
1609-9419
1025-5583
reponame:Revistas - Universidad Nacional Mayor de San Marcos
instname:Universidad Nacional Mayor de San Marcos
instacron:UNMSM
instname_str Universidad Nacional Mayor de San Marcos
instacron_str UNMSM
institution UNMSM
reponame_str Revistas - Universidad Nacional Mayor de San Marcos
collection Revistas - Universidad Nacional Mayor de San Marcos
repository.name.fl_str_mv
repository.mail.fl_str_mv
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Constitutional hepatic dysfunction (Gilbert's disease), about eleven cases studied in the Hospital Obrero de Lima
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