Phenomenon "LE" and electrophoresis of serum proteins in the study of systemic lupus erythematosus

Descripción del Articulo

We present the results of tests and LE electrophoresis of serum proteins made ​​in a number of patients in the course of a study of SLE and related diseases. 120 LE cell research on a group of 83 patients were performed. The test was positive in 29/30 cases of SLE, giving a 96.7%. He was positive al...

Descripción completa

Detalles Bibliográficos
Autor: Stastny M., Pedro
Formato: artículo
Fecha de Publicación:1958
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Lenguaje:español
OAI Identifier:oai:ojs.csi.unmsm:article/8957
Enlace del recurso:https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/8957
Nivel de acceso:acceso abierto
id REVUNMSM_81e975d2f40b81aa71b3fc28ddf4070f
oai_identifier_str oai:ojs.csi.unmsm:article/8957
network_acronym_str REVUNMSM
network_name_str Revistas - Universidad Nacional Mayor de San Marcos
repository_id_str
spelling Phenomenon "LE" and electrophoresis of serum proteins in the study of systemic lupus erythematosusFenómeno "LE" y la electroforesis de las proteínas séricas en el estudio del lupus eritematoso sistémicoStastny M., PedroWe present the results of tests and LE electrophoresis of serum proteins made ​​in a number of patients in the course of a study of SLE and related diseases. 120 LE cell research on a group of 83 patients were performed. The test was positive in 29/30 cases of SLE, giving a 96.7%. He was positive also in cases of scleroderma 4/9 investigated (44.4%). All other tests were negative. 100 electrophoretic determinations were made. Serial studies in 34 patients with positive LE test and 20 tests in normal controls assumptions. In cases where the known pattern LES decrease albumin, gamma-globulin increased elevation of prevalent and alpha-2-globulin found. Correlation between clinical improvement and serum proteins was observed. In some cases, significant changes in the levels of serum proteins fractions occurred rapidly. A case where relation between the results of electrophoresis and the temperature of the patient is observed is presented. There was no correlation between serum proteins and the LE phenomenon. The findings described noting the value of both tests in the clinical study of patients are discussed.Se presentan los resultados de las pruebas LE y de la electroforesis de las seroproteínas practicadas en una serie de pacientes en el curso de un estudio sobre LES y enfermedades relacionadas. Se practicaron 120 investigaciones de células LE, sobre un grupo de 83 pacientes. La prueba fué positiva en 29/30 casos de LES, lo que da un 96.7%. Fué positiva también en 4/9 casos de esclerodemia investigados (44.4%). Todas las demás pruebas fueron negativas. Se hicieron 100 determinaciones electroforéticas. Estudios seriados en 34 enfermos con prueba LE positiva y 20 determinaciones en controles supuestos normales. En los casos de LES se encontró el conocido patrón de disminución de albúmina, aumento de gama-globulina y frecuente elevación de alfa-2-globulina. Se observó correlación entre la evolución del cuadro clínico y la de las proteínas séricas. En algunos casos cambios significativos de los niveles de las fracciones de seroproteínas se produjeron con gran rapidez. Se presenta un caso en que se observó relación entre los resultados de electroforesis y la temperatura de la paciente. No hubo correlación entre las proteínas séricas y el fenómeno LE. Se discuten los hallazgos descritos señalando el valor de ambas pruebas en el estudio clínico de los enfermos.Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana1958-06-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/895710.15381/anales.v41i2.8957Anales de la Facultad de Medicina; Vol. 41 No. 2 (1958); 278-301Anales de la Facultad de Medicina; Vol. 41 Núm. 2 (1958); 278-3011609-94191025-5583reponame:Revistas - Universidad Nacional Mayor de San Marcosinstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMspahttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/8957/7783Derechos de autor 1958 Pedro Stastny M.https://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessoai:ojs.csi.unmsm:article/89572020-04-08T12:01:52Z
dc.title.none.fl_str_mv Phenomenon "LE" and electrophoresis of serum proteins in the study of systemic lupus erythematosus
Fenómeno "LE" y la electroforesis de las proteínas séricas en el estudio del lupus eritematoso sistémico
title Phenomenon "LE" and electrophoresis of serum proteins in the study of systemic lupus erythematosus
spellingShingle Phenomenon "LE" and electrophoresis of serum proteins in the study of systemic lupus erythematosus
Stastny M., Pedro
title_short Phenomenon "LE" and electrophoresis of serum proteins in the study of systemic lupus erythematosus
title_full Phenomenon "LE" and electrophoresis of serum proteins in the study of systemic lupus erythematosus
title_fullStr Phenomenon "LE" and electrophoresis of serum proteins in the study of systemic lupus erythematosus
title_full_unstemmed Phenomenon "LE" and electrophoresis of serum proteins in the study of systemic lupus erythematosus
title_sort Phenomenon "LE" and electrophoresis of serum proteins in the study of systemic lupus erythematosus
dc.creator.none.fl_str_mv Stastny M., Pedro
author Stastny M., Pedro
author_facet Stastny M., Pedro
author_role author
description We present the results of tests and LE electrophoresis of serum proteins made ​​in a number of patients in the course of a study of SLE and related diseases. 120 LE cell research on a group of 83 patients were performed. The test was positive in 29/30 cases of SLE, giving a 96.7%. He was positive also in cases of scleroderma 4/9 investigated (44.4%). All other tests were negative. 100 electrophoretic determinations were made. Serial studies in 34 patients with positive LE test and 20 tests in normal controls assumptions. In cases where the known pattern LES decrease albumin, gamma-globulin increased elevation of prevalent and alpha-2-globulin found. Correlation between clinical improvement and serum proteins was observed. In some cases, significant changes in the levels of serum proteins fractions occurred rapidly. A case where relation between the results of electrophoresis and the temperature of the patient is observed is presented. There was no correlation between serum proteins and the LE phenomenon. The findings described noting the value of both tests in the clinical study of patients are discussed.
publishDate 1958
dc.date.none.fl_str_mv 1958-06-16
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/8957
10.15381/anales.v41i2.8957
url https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/8957
identifier_str_mv 10.15381/anales.v41i2.8957
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/8957/7783
dc.rights.none.fl_str_mv Derechos de autor 1958 Pedro Stastny M.
https://creativecommons.org/licenses/by-nc-sa/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Derechos de autor 1958 Pedro Stastny M.
https://creativecommons.org/licenses/by-nc-sa/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana
publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana
dc.source.none.fl_str_mv Anales de la Facultad de Medicina; Vol. 41 No. 2 (1958); 278-301
Anales de la Facultad de Medicina; Vol. 41 Núm. 2 (1958); 278-301
1609-9419
1025-5583
reponame:Revistas - Universidad Nacional Mayor de San Marcos
instname:Universidad Nacional Mayor de San Marcos
instacron:UNMSM
instname_str Universidad Nacional Mayor de San Marcos
instacron_str UNMSM
institution UNMSM
reponame_str Revistas - Universidad Nacional Mayor de San Marcos
collection Revistas - Universidad Nacional Mayor de San Marcos
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1795238249480847360
score 13.897891
Phenomenon "LE" and electrophoresis of serum proteins in the study of systemic lupus erythematosus
Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).

Ejemplares Similares