In Vitro Screening for Antimicrobial and Antioxidant of a meditational plant: Ziziphus jujube leaves
Descripción del Articulo
        The current study explore was designed for the investigation of antimicrobial and antioxidant activity of crude methanol extract of the plant Ziziphus jujuba. The crude methanol extract and other extracts showed considerable total antioxidant activity and reducing capacity. In DPPH scavenging test,...
              
            
    
                        | Autores: | , , | 
|---|---|
| Formato: | artículo | 
| Fecha de Publicación: | 2021 | 
| Institución: | Universidad Nacional Mayor de San Marcos | 
| Repositorio: | Revistas - Universidad Nacional Mayor de San Marcos | 
| Lenguaje: | inglés | 
| OAI Identifier: | oai:ojs.csi.unmsm:article/22326 | 
| Enlace del recurso: | https://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/22326 | 
| Nivel de acceso: | acceso abierto | 
| Materia: | Ziziphus jujube Antimicrobial activities DPPH scavenging Antioxidant Actividad antimicrobiana DPPH Antioxidante  | 
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                  In Vitro Screening for Antimicrobial and Antioxidant of a meditational plant: Ziziphus jujube leavesDetección in vitro de actividades antimicrobianos y antioxidantes de una planta meditacional: Hojas de Ziziphus jujubeIslam, SharifulHossain, MoazzemAkter, AmenaIslam, SharifulHossain, MoazzemAkter, AmenaZiziphus jujubeAntimicrobial activitiesDPPH scavengingAntioxidantZiziphus jujubeActividad antimicrobianaDPPHAntioxidanteThe current study explore was designed for the investigation of antimicrobial and antioxidant activity of crude methanol extract of the plant Ziziphus jujuba. The crude methanol extract and other extracts showed considerable total antioxidant activity and reducing capacity. In DPPH scavenging test, the crude extract showed 83.02% scavenging having IC50 of 22.23 μg/ml. Amongst the fractions, petroleum ether fraction demonstrated the highest DPPH scavenging activity with IC50 of 62.45 μg/ml, as long as, chloroform extract exhibited the lowest activity with IC50 of 32.13 μg/ml and N-hexane fraction with IC50 of 58.45 μg/ml. The presences of endogenous substances in Ziziphus jujuba that may act as antioxidant were established by measuring the total content of phenolic and flavonoid activities. In antimicrobial activities, the petroleum ether and methanol extract showed significant activity of 15-18 mm and 11-16 mm zone of inhibition against Bacillus cereus and micrococcus luteus respectively.El estudio actual fué diseñado para la investigación de la actividad antimicrobiana y antioxidante del extracto de metanol crudo de la planta Ziziphus jujuba. El extracto metanólico crudo y otros extractos mostraron una considerable actividad antioxidante total y capacidad reductora. En la prueba de eliminación de DPPH, el extracto crudo mostró una eliminación del 83,02 % con una IC50 de 22,23 μg/ml. Entre las fracciones, la fracción de éter de petróleo demostró la mayor actividad de eliminación de DPPH con IC50 de 62,45 μg/ml, mientras que el extracto de cloroformo exhibió la actividad más baja con IC50 de 32,13 μg/ml y la fracción de N-hexano con IC50 de 58,45 μg/ml. . La presencia de sustancias endógenas en Ziziphus jujuba que pueden actuar como antioxidante se establecieron midiendo el contenido total de actividades fenólicas y flavonoides. En actividades antimicrobianas, el éter de petróleo y el extracto de metanol mostraron una actividad significativa de 15-18 mm y 11-16 mm de zona de inhibición contra Bacillus cereus y micrococcus luteus respectivamente.Universidad Nacional Mayor de San Marcos, Facultad de Farmacia y Bioquímica2021-12-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/2232610.15381/ci.v24i1.22326Ciencia e Investigación; Vol. 24 Núm. 1 (2021); 47-54Ciencia e Investigación; Vol. 24 No. 1 (2021); 47-541609-90441561-0861reponame:Revistas - Universidad Nacional Mayor de San Marcosinstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMenghttps://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/22326/17934Derechos de autor 2021 Shariful Islam, Moazzem Hossain, Amena Akterhttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessoai:ojs.csi.unmsm:article/223262022-02-28T12:52:09Z | 
    
| dc.title.none.fl_str_mv | 
                  In Vitro Screening for Antimicrobial and Antioxidant of a meditational plant: Ziziphus jujube leaves Detección in vitro de actividades antimicrobianos y antioxidantes de una planta meditacional: Hojas de Ziziphus jujube  | 
    
| title | 
                  In Vitro Screening for Antimicrobial and Antioxidant of a meditational plant: Ziziphus jujube leaves | 
    
| spellingShingle | 
                  In Vitro Screening for Antimicrobial and Antioxidant of a meditational plant: Ziziphus jujube leaves Islam, Shariful Ziziphus jujube Antimicrobial activities DPPH scavenging Antioxidant Ziziphus jujube Actividad antimicrobiana DPPH Antioxidante  | 
    
| title_short | 
                  In Vitro Screening for Antimicrobial and Antioxidant of a meditational plant: Ziziphus jujube leaves | 
    
| title_full | 
                  In Vitro Screening for Antimicrobial and Antioxidant of a meditational plant: Ziziphus jujube leaves | 
    
| title_fullStr | 
                  In Vitro Screening for Antimicrobial and Antioxidant of a meditational plant: Ziziphus jujube leaves | 
    
| title_full_unstemmed | 
                  In Vitro Screening for Antimicrobial and Antioxidant of a meditational plant: Ziziphus jujube leaves | 
    
| title_sort | 
                  In Vitro Screening for Antimicrobial and Antioxidant of a meditational plant: Ziziphus jujube leaves | 
    
| dc.creator.none.fl_str_mv | 
                  Islam, Shariful Hossain, Moazzem Akter, Amena Islam, Shariful Hossain, Moazzem Akter, Amena  | 
    
| author | 
                  Islam, Shariful | 
    
| author_facet | 
                  Islam, Shariful Hossain, Moazzem Akter, Amena  | 
    
| author_role | 
                  author | 
    
| author2 | 
                  Hossain, Moazzem Akter, Amena  | 
    
| author2_role | 
                  author author  | 
    
| dc.subject.none.fl_str_mv | 
                  Ziziphus jujube Antimicrobial activities DPPH scavenging Antioxidant Ziziphus jujube Actividad antimicrobiana DPPH Antioxidante  | 
    
| topic | 
                  Ziziphus jujube Antimicrobial activities DPPH scavenging Antioxidant Ziziphus jujube Actividad antimicrobiana DPPH Antioxidante  | 
    
| description | 
                  The current study explore was designed for the investigation of antimicrobial and antioxidant activity of crude methanol extract of the plant Ziziphus jujuba. The crude methanol extract and other extracts showed considerable total antioxidant activity and reducing capacity. In DPPH scavenging test, the crude extract showed 83.02% scavenging having IC50 of 22.23 μg/ml. Amongst the fractions, petroleum ether fraction demonstrated the highest DPPH scavenging activity with IC50 of 62.45 μg/ml, as long as, chloroform extract exhibited the lowest activity with IC50 of 32.13 μg/ml and N-hexane fraction with IC50 of 58.45 μg/ml. The presences of endogenous substances in Ziziphus jujuba that may act as antioxidant were established by measuring the total content of phenolic and flavonoid activities. In antimicrobial activities, the petroleum ether and methanol extract showed significant activity of 15-18 mm and 11-16 mm zone of inhibition against Bacillus cereus and micrococcus luteus respectively. | 
    
| publishDate | 
                  2021 | 
    
| dc.date.none.fl_str_mv | 
                  2021-12-31 | 
    
| dc.type.none.fl_str_mv | 
                  info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion  | 
    
| format | 
                  article | 
    
| status_str | 
                  publishedVersion | 
    
| dc.identifier.none.fl_str_mv | 
                  https://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/22326 10.15381/ci.v24i1.22326  | 
    
| url | 
                  https://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/22326 | 
    
| identifier_str_mv | 
                  10.15381/ci.v24i1.22326 | 
    
| dc.language.none.fl_str_mv | 
                  eng | 
    
| language | 
                  eng | 
    
| dc.relation.none.fl_str_mv | 
                  https://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/22326/17934 | 
    
| dc.rights.none.fl_str_mv | 
                  Derechos de autor 2021 Shariful Islam, Moazzem Hossain, Amena Akter http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess  | 
    
| rights_invalid_str_mv | 
                  Derechos de autor 2021 Shariful Islam, Moazzem Hossain, Amena Akter http://creativecommons.org/licenses/by/4.0  | 
    
| eu_rights_str_mv | 
                  openAccess | 
    
| dc.format.none.fl_str_mv | 
                  application/pdf | 
    
| dc.publisher.none.fl_str_mv | 
                  Universidad Nacional Mayor de San Marcos, Facultad de Farmacia y Bioquímica | 
    
| publisher.none.fl_str_mv | 
                  Universidad Nacional Mayor de San Marcos, Facultad de Farmacia y Bioquímica | 
    
| dc.source.none.fl_str_mv | 
                  Ciencia e Investigación; Vol. 24 Núm. 1 (2021); 47-54 Ciencia e Investigación; Vol. 24 No. 1 (2021); 47-54 1609-9044 1561-0861 reponame:Revistas - Universidad Nacional Mayor de San Marcos instname:Universidad Nacional Mayor de San Marcos instacron:UNMSM  | 
    
| instname_str | 
                  Universidad Nacional Mayor de San Marcos | 
    
| instacron_str | 
                  UNMSM | 
    
| institution | 
                  UNMSM | 
    
| reponame_str | 
                  Revistas - Universidad Nacional Mayor de San Marcos | 
    
| collection | 
                  Revistas - Universidad Nacional Mayor de San Marcos | 
    
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                  1795238297972244480 | 
    
| score | 
                  13.977305 | 
    
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    La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).