Clinical Study Primary Myocardial Disease

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We studied 26 patients with cardiomyopathy in the span of 10 years ( 1960-1970 ) , and originating from different regions of the country; 24 cases were males and 2 were females. Thirteen patients corresponded to the called idiopathic cardiomyopathy , 8 were related to alcoholism , 3 were familial, a...

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Autor: Batillana Guanilo, Carlos Alberto
Formato: artículo
Fecha de Publicación:1971
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Lenguaje:español
OAI Identifier:oai:ojs.csi.unmsm:article/5041
Enlace del recurso:https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/5041
Nivel de acceso:acceso abierto
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dc.title.none.fl_str_mv Clinical Study Primary Myocardial Disease
Estudio Clinico De Enfermedad Miocárdica Primaria
title Clinical Study Primary Myocardial Disease
spellingShingle Clinical Study Primary Myocardial Disease
Batillana Guanilo, Carlos Alberto
title_short Clinical Study Primary Myocardial Disease
title_full Clinical Study Primary Myocardial Disease
title_fullStr Clinical Study Primary Myocardial Disease
title_full_unstemmed Clinical Study Primary Myocardial Disease
title_sort Clinical Study Primary Myocardial Disease
dc.creator.none.fl_str_mv Batillana Guanilo, Carlos Alberto
author Batillana Guanilo, Carlos Alberto
author_facet Batillana Guanilo, Carlos Alberto
author_role author
description We studied 26 patients with cardiomyopathy in the span of 10 years ( 1960-1970 ) , and originating from different regions of the country; 24 cases were males and 2 were females. Thirteen patients corresponded to the called idiopathic cardiomyopathy , 8 were related to alcoholism , 3 were familial, a case of postpartum disease and one with endomyocardial fibrosis . The ages ranged from 13 to 65, with an average of 41.8 years. Clinically, all patients, except one , had manifestations of heart failure with varying physical findings predominance the existence of cardiomegaly , systemic venous hypertension and gallop . In only one case the symptoms were related exclusively to multiple embolism. The most common arrhythmias were extrasystolic type , having demonstrated atrial fibrillation or flutter in 5 cases. The electrocardiographic patterns were also varied , showing preferably a combination lock intraventricular low voltage ; electrocardiogram was within normal limits in only one patient , who died with cardiomegaly and heart failure. Radiology showed a predominance of cardiac enlargement left cavities in virtually all cases. Fourteen patients died, necropsy performed on all of them . Macroscopic study of the heart was abnormal in 13 cases , showing dilatation and hypertrophy , only one case of a heart was found normal appearance . However, in all cases studied histology indicated that mainly changes committed to the myocardial fibers in the form of myocytolysis , nuclear changes and unspecific changes in the interstitial tissue ; these alterations were common to many patients and not keep apparent relation to the different clinical pictures. Abnormalities or inflammatory atherosclerotic were negligible.
publishDate 1971
dc.date.none.fl_str_mv 1971-09-20
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/5041
10.15381/anales.v54i3.5041
url https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/5041
identifier_str_mv 10.15381/anales.v54i3.5041
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/5041/4121
dc.rights.none.fl_str_mv Derechos de autor 1971 Carlos Alberto Batillana Guanilo
https://creativecommons.org/licenses/by-nc-sa/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Derechos de autor 1971 Carlos Alberto Batillana Guanilo
https://creativecommons.org/licenses/by-nc-sa/4.0
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dc.publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana
publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana
dc.source.none.fl_str_mv Anales de la Facultad de Medicina; Vol. 54 No. 3 (1971); 262-305
Anales de la Facultad de Medicina; Vol. 54 Núm. 3 (1971); 262-305
1609-9419
1025-5583
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spelling Clinical Study Primary Myocardial DiseaseEstudio Clinico De Enfermedad Miocárdica PrimariaBatillana Guanilo, Carlos AlbertoWe studied 26 patients with cardiomyopathy in the span of 10 years ( 1960-1970 ) , and originating from different regions of the country; 24 cases were males and 2 were females. Thirteen patients corresponded to the called idiopathic cardiomyopathy , 8 were related to alcoholism , 3 were familial, a case of postpartum disease and one with endomyocardial fibrosis . The ages ranged from 13 to 65, with an average of 41.8 years. Clinically, all patients, except one , had manifestations of heart failure with varying physical findings predominance the existence of cardiomegaly , systemic venous hypertension and gallop . In only one case the symptoms were related exclusively to multiple embolism. The most common arrhythmias were extrasystolic type , having demonstrated atrial fibrillation or flutter in 5 cases. The electrocardiographic patterns were also varied , showing preferably a combination lock intraventricular low voltage ; electrocardiogram was within normal limits in only one patient , who died with cardiomegaly and heart failure. Radiology showed a predominance of cardiac enlargement left cavities in virtually all cases. Fourteen patients died, necropsy performed on all of them . Macroscopic study of the heart was abnormal in 13 cases , showing dilatation and hypertrophy , only one case of a heart was found normal appearance . However, in all cases studied histology indicated that mainly changes committed to the myocardial fibers in the form of myocytolysis , nuclear changes and unspecific changes in the interstitial tissue ; these alterations were common to many patients and not keep apparent relation to the different clinical pictures. Abnormalities or inflammatory atherosclerotic were negligible.Se han estudiado 26 pacientes con cardiomiopatía en el lapso de 10 años (1960 - 1970), originarios y provenientes de diferentes regiones del país; 24 casos pertenecieron al sexo masculino y 2 al femenino. Trece pacientes correspondieron a la llamada cardiomiopatía idiopática, 8 estuvieron relacionados al alcoholismo, 3 fueron de tipo familiar, un caso de cardiopatía postpartum y otro con endomiocardiofibrosis. Las edades fluctuaron entre 13 y 65 años, con un promedio de 41.8 años. Clínicamente, todos los pacientes, con excepción de uno, presentaron manifestaciones de insuficiencia cardíaca con hallazgos variados al examen físico, predominando la existencia de cardiomegalia, hipertensión venosa sistémica y ritmo de galope. En solamente un caso la sintomatología estuvo relacionada exclusivamente a embolismo múltiple. Las arritmias más frecuentes fueron de tipo extrasistólico, habiéndose demostrado fibrilación o flutter auricular en 5 casos. Los patrones electrocardiográficos fueron también variados, observándose de preferencia una combinación de bloqueo intraventricular con bajo voltaje; el electrocardiograma estuvo dentro de los límites normales en sólo un paciente, el cual falleció con cardiomegalia e insuficiencia cardíaca. La radiología demostró crecimiento cardíaco a predominio de cavidades izquierdas en, prácticamente, todos los casos. Catorce pacientes fallecieron, realizándose la necropsia en todos ellos. El estudio macroscópico del corazón fue anormal en 13 casos, mostrando dilatación e hipertrofia, sólo en un caso se halló un corazón de aspecto normal. Sin embargo, en todos los casos estudiados el examen histológico indicó alteraciones que principalmente comprometían a la fibra miocárdica, en forma de miocitolisis, alteraciones nucleares y cambios inespecíficos en el tejido intersticial; estas alteraciones fueron comunes a muchos pacientes y no guardaron relación aparente con los diferentes cuadros clínicos. Las anormalidades de tipo ateroesclerótico o inflamatorio fueron insignificantes.Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana1971-09-20info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/504110.15381/anales.v54i3.5041Anales de la Facultad de Medicina; Vol. 54 No. 3 (1971); 262-305Anales de la Facultad de Medicina; Vol. 54 Núm. 3 (1971); 262-3051609-94191025-5583reponame:Revistas - Universidad Nacional Mayor de San Marcosinstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMspahttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/5041/4121Derechos de autor 1971 Carlos Alberto Batillana Guanilohttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessoai:ojs.csi.unmsm:article/50412020-04-12T17:11:15Z
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