Validez diagnóstica del volumen plaquetario medio en sepsis neonatal: una revisión sistemática: Diagnostic validity of mean platelet volume in neonatal sepsis: a systematic review

• Autores: Sánchez-Reyna, Víctor Andrés, Milla-León, Sarella Belen, Monzón-Ascensio, Emilia Thayli, Nima-Blas, Juan Alberto, Niquin-Huancajulca, Ronal, Nolly-Loyaga, Angie Stephanie, Otiniano-Ramos, Lucio Fernando, Huamán-Rodríguez, Martina Rosaria
• Formato: artículo
• Fecha de Publicación: 2022
• Institución: Universidad Nacional de Trujillo
• Repositorio: Revistas - Universidad Nacional de Trujillo
• Lenguaje: español
• OAI Identifier: oai:ojs.revistas.unitru.edu.pe:article/5003
• Enlace del recurso: https://revistas.unitru.edu.pe/index.php/RMT/article/view/5003
• Nivel de acceso: acceso abierto
• Materia: sepsis neonatal; VPM; utilidad diagnóstica; neonatal sepsis; MPV; diagnostic utility

A systematic review study was carried out according to the standards of the PRISMA guide. We searched Medline, Pubmed, Central Cochrane and Embase databases. Observational studies (case-control and cohorts) that were published no more than 5 years ago and studied MPV as a diagnostic marker of NS, were included. From 60 articles identified, 12 were selected to be analyzed. We found that the diagnostic cut-off point for MPV ranged between 9.2 and 10.8 fL. In addition, the highest reported diagnostic sensitivity was 100%, and the lowest, 70%; while the specificity ranged from 33% to 94.4% according to each study. Conclusion: The MPV has a high sensitivity for the diagnosis of NS, however, the analyzed studies show a highly variable specificity.