Correlations between neuropsychiatric symptoms and executive dysfunction in Alzheimer’s Disease

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Objective: To explore the correlations between neuropsychiatric symptoms and executive dysfunction in Alzheimer’s Disease (AD). Patients and method: In a sample of 39 patients with AD the following instruments were used: the NeuroPsychiatric Inventory Questionnarie (NPI-Q) to assess the fre...

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Detalles Bibliográficos
Autor: Sotomayor, Paloma A.
Formato: artículo
Fecha de Publicación:2007
Institución:Universidad de Lima
Repositorio:Revistas - Universidad de Lima
Lenguaje:español
OAI Identifier:oai:revistas.ulima.edu.pe:article/916
Enlace del recurso:https://revistas.ulima.edu.pe/index.php/Persona/article/view/916
Nivel de acceso:acceso abierto
Materia:alzheimer’s disease
neuropsychiatric symptoms
executive dysfunction
frontal lobe
enfermedad de Alzheimer
síntomas neuropsiquiátricos
disfunción ejecutiva
lóbulo frontal
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spelling Correlations between neuropsychiatric symptoms and executive dysfunction in Alzheimer’s DiseaseCorrelación entre la frecuencia de síntomas neuropsiquiátricos y de disfunción ejecutiva en pacientes con enfermedad de Alzheimer: Estudio exploratorioSotomayor, Paloma A.alzheimer’s diseaseneuropsychiatric symptomsexecutive dysfunctionfrontal lobeenfermedad de Alzheimersíntomas neuropsiquiátricosdisfunción ejecutivalóbulo frontalObjective: To explore the correlations between neuropsychiatric symptoms and executive dysfunction in Alzheimer’s Disease (AD). Patients and method: In a sample of 39 patients with AD the following instruments were used: the NeuroPsychiatric Inventory Questionnarie (NPI-Q) to assess the frequency of neuropsychiatric symptoms, the Frontal Assessment Battery (FAB)to assess executive dysfunction, and the Mini Mental State Examination (MMSE) to divide the sample into subgroups depending on level of cognitive impairment. Results: Negative correlations were found between prehension behavior and the frequency of euphoria/exaltation, sleep disorders, disinhibition and hallucinations. Unexpected positive correlations were also found between sensitivity to interference and hallucinations; motor sequences and disinhibition and eating disorders; verbal fluency and eating disorders; and Go-No go and euphoria/exaltation.El objetivo de este estudio es explorar correlaciones entre la frecuencia de síntomas neuropsiquiátricos y la disfunción ejecutiva en la enfermedad de Alzheimer (EA). Se trabajó con muestra de 39 pacientes con EA y se utilizó el NeuroPsychiatric Inventory Questionnarie (NPI-Q) para valorar la frecuencia de síntomas neuropsiquiátricos, el Frontal Assessment Battery (FAB)para observar la disfunción ejecutiva y el Mini Mental State Examination (MMSE) para dividir la muestra en subgrupos según deterioro cognitivo. Al culminar el estudio se encontraron correlaciones negativas entre la conducta de prehensión y la frecuencia de exaltación/euforia, trastornos del sueño, desinhibición y alucinaciones. Además se encontraron correlaciones positivas no esperadas entre sensibilidad a la interferencia y alucinaciones; secuencias motoras y desinhibición y trastornos de alimentación; fluencia verbal y trastornos de alimentación; y Go-No go y exaltación/euforia.    Universidad de Lima2007-11-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistas.ulima.edu.pe/index.php/Persona/article/view/91610.26439/persona2007.n010.916Persona; No. 010 (2007); 125-159Persona; Núm. 010 (2007); 125-159Persona; n. 010 (2007); 125-1592309-90621560-613910.26439/persona2007.n010reponame:Revistas - Universidad de Limainstname:Universidad de Limainstacron:ULIMAspahttps://revistas.ulima.edu.pe/index.php/Persona/article/view/916/865https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:revistas.ulima.edu.pe:article/9162024-10-21T14:11:05Z
dc.title.none.fl_str_mv Correlations between neuropsychiatric symptoms and executive dysfunction in Alzheimer’s Disease
Correlación entre la frecuencia de síntomas neuropsiquiátricos y de disfunción ejecutiva en pacientes con enfermedad de Alzheimer: Estudio exploratorio
title Correlations between neuropsychiatric symptoms and executive dysfunction in Alzheimer’s Disease
spellingShingle Correlations between neuropsychiatric symptoms and executive dysfunction in Alzheimer’s Disease
Sotomayor, Paloma A.
alzheimer’s disease
neuropsychiatric symptoms
executive dysfunction
frontal lobe
enfermedad de Alzheimer
síntomas neuropsiquiátricos
disfunción ejecutiva
lóbulo frontal
title_short Correlations between neuropsychiatric symptoms and executive dysfunction in Alzheimer’s Disease
title_full Correlations between neuropsychiatric symptoms and executive dysfunction in Alzheimer’s Disease
title_fullStr Correlations between neuropsychiatric symptoms and executive dysfunction in Alzheimer’s Disease
title_full_unstemmed Correlations between neuropsychiatric symptoms and executive dysfunction in Alzheimer’s Disease
title_sort Correlations between neuropsychiatric symptoms and executive dysfunction in Alzheimer’s Disease
dc.creator.none.fl_str_mv Sotomayor, Paloma A.
author Sotomayor, Paloma A.
author_facet Sotomayor, Paloma A.
author_role author
dc.subject.none.fl_str_mv alzheimer’s disease
neuropsychiatric symptoms
executive dysfunction
frontal lobe
enfermedad de Alzheimer
síntomas neuropsiquiátricos
disfunción ejecutiva
lóbulo frontal
topic alzheimer’s disease
neuropsychiatric symptoms
executive dysfunction
frontal lobe
enfermedad de Alzheimer
síntomas neuropsiquiátricos
disfunción ejecutiva
lóbulo frontal
description Objective: To explore the correlations between neuropsychiatric symptoms and executive dysfunction in Alzheimer’s Disease (AD). Patients and method: In a sample of 39 patients with AD the following instruments were used: the NeuroPsychiatric Inventory Questionnarie (NPI-Q) to assess the frequency of neuropsychiatric symptoms, the Frontal Assessment Battery (FAB)to assess executive dysfunction, and the Mini Mental State Examination (MMSE) to divide the sample into subgroups depending on level of cognitive impairment. Results: Negative correlations were found between prehension behavior and the frequency of euphoria/exaltation, sleep disorders, disinhibition and hallucinations. Unexpected positive correlations were also found between sensitivity to interference and hallucinations; motor sequences and disinhibition and eating disorders; verbal fluency and eating disorders; and Go-No go and euphoria/exaltation.
publishDate 2007
dc.date.none.fl_str_mv 2007-11-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistas.ulima.edu.pe/index.php/Persona/article/view/916
10.26439/persona2007.n010.916
url https://revistas.ulima.edu.pe/index.php/Persona/article/view/916
identifier_str_mv 10.26439/persona2007.n010.916
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistas.ulima.edu.pe/index.php/Persona/article/view/916/865
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info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad de Lima
publisher.none.fl_str_mv Universidad de Lima
dc.source.none.fl_str_mv Persona; No. 010 (2007); 125-159
Persona; Núm. 010 (2007); 125-159
Persona; n. 010 (2007); 125-159
2309-9062
1560-6139
10.26439/persona2007.n010
reponame:Revistas - Universidad de Lima
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reponame_str Revistas - Universidad de Lima
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