Invasive hydatidiform mole coexistent with normal fetus. Case report

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We report the case of a pregnant woman referred to our hospital for suspected partial hydatidiform mole. Ultrasound images showed a normal fetus attached to a small placenta adjacent to a honeycomb-like tumor mass. Amniocentesis revealed a normal karyotype. Due to β-hCG values greater than 800 000 I...

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Detalles Bibliográficos
Autores: Tipiani Rodríguez, Oswaldo, Solís Sosa, Carlos, Valdez Alegría, Grace Elizabeth, Quenaya Rodríguez, Roberth Jonathan, Escalante Jibaja, Ricardo, Cevallos Pacheco, Carlos, Ibarra Lavado, Oscar, Bocanegra Becerra, Yuliana Libet
Formato: artículo
Fecha de Publicación:2020
Institución:Sociedad Peruana de Obstetricia y Ginecología
Repositorio:Revista Peruana de Ginecología y Obstetricia
Lenguaje:español
inglés
OAI Identifier:oai:ginecologiayobstetricia.pe:article/2253
Enlace del recurso:https://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2253
Nivel de acceso:acceso abierto
Materia:Pregnancy
Hydatidiform mole
Invasive
Fetus
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spelling Invasive hydatidiform mole coexistent with normal fetus. Case reportMola invasiva coexistente con feto vivo normal. Reporte de casoTipiani Rodríguez, OswaldoSolís Sosa, CarlosValdez Alegría, Grace ElizabethQuenaya Rodríguez, Roberth JonathanEscalante Jibaja, RicardoCevallos Pacheco, CarlosIbarra Lavado, OscarBocanegra Becerra, Yuliana LibetPregnancyHydatidiform moleInvasiveFetusWe report the case of a pregnant woman referred to our hospital for suspected partial hydatidiform mole. Ultrasound images showed a normal fetus attached to a small placenta adjacent to a honeycomb-like tumor mass. Amniocentesis revealed a normal karyotype. Due to β-hCG values greater than 800 000 IU and a mass growth of 11% by magnetic resonance imaging, an ultrasound-guided percutaneous tumor biopsy was performed; it ruled out the possibility of choriocarcinoma. The patient had symptoms of hyperthyroidism that required treatment; when the β-HCG levels exceeded one million IU, a course of chemotherapy was prescribed. At 29 weeks, the patient started labor; a cesarean hysterectomy was performed, obtaining a live newborn with Apgar 5 and 7. The pathology report informed the placental mass as an invasive mole. According to our literature search, this is the first case report where an invasive mole coexisted with a healthy fetus. We highlight the importance of using all diagnostic and management tools necessary to achieve fetal viability, without increasing the maternal risk of complications.Comunicamos el caso de una gestante referida por sospecha de mola parcial. Las imágenes ultrasonográficas mostraban un feto normal unido a placenta pequeña, adyacente a una masa tumoral en ‘panal de abejas’. Se realizó amniocentesis, con resultado de cariotipo normal. Debido a valores de hCG-β superiores a 800 000 UI y crecimiento de la masa de 11% a la resonancia magnética, se realizó biopsia tumoral percutánea guiada por ecografía, la cual alejó la posibilidad de coriocarcinoma. La paciente hizo síntomas de hipertiroidismo que requirieron tratamiento y, al superar la hCG-β el millón de unidades, se decidió dar un curso de quimioterapia. A las 29 semanas inició trabajo de parto; se realizó cesárea-histerectomía, obteniéndose recién nacido vivo, con Apgar 5 y 7. Al examen anatomopatológico, la masa placentaria resultó mola invasiva. De acuerdo con nuestra búsqueda, se comunica el primer caso en la literatura de coexistencia de mola invasiva con feto sano, y resaltamos la importancia de usar las herramientas diagnósticas y de manejo necesarias para lograr la viabilidad del producto de la concepción, sin incrementar el riesgo materno.Sociedad Peruana de Obstetricia y Ginecología2020-06-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://ginecologiayobstetricia.pe/index.php/RPGO/article/view/225310.31403/rpgo.v66i2253The Peruvian Journal of Gynecology and Obstetrics ; Vol. 66 No. 2 (2020)Revista Peruana de Ginecología y Obstetricia; Vol. 66 Núm. 2 (2020)2304-51322304-5124reponame:Revista Peruana de Ginecología y Obstetriciainstname:Sociedad Peruana de Obstetricia y Ginecologíainstacron:SPOGspaenghttps://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2253/pdfhttps://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2253/pdf_1Derechos de autor 2020 Revista Peruana de Ginecología y Obstetriciainfo:eu-repo/semantics/openAccessoai:ginecologiayobstetricia.pe:article/22532026-01-12T16:27:25Z
dc.title.none.fl_str_mv Invasive hydatidiform mole coexistent with normal fetus. Case report
Mola invasiva coexistente con feto vivo normal. Reporte de caso
title Invasive hydatidiform mole coexistent with normal fetus. Case report
spellingShingle Invasive hydatidiform mole coexistent with normal fetus. Case report
Tipiani Rodríguez, Oswaldo
Pregnancy
Hydatidiform mole
Invasive
Fetus
title_short Invasive hydatidiform mole coexistent with normal fetus. Case report
title_full Invasive hydatidiform mole coexistent with normal fetus. Case report
title_fullStr Invasive hydatidiform mole coexistent with normal fetus. Case report
title_full_unstemmed Invasive hydatidiform mole coexistent with normal fetus. Case report
title_sort Invasive hydatidiform mole coexistent with normal fetus. Case report
dc.creator.none.fl_str_mv Tipiani Rodríguez, Oswaldo
Solís Sosa, Carlos
Valdez Alegría, Grace Elizabeth
Quenaya Rodríguez, Roberth Jonathan
Escalante Jibaja, Ricardo
Cevallos Pacheco, Carlos
Ibarra Lavado, Oscar
Bocanegra Becerra, Yuliana Libet
author Tipiani Rodríguez, Oswaldo
author_facet Tipiani Rodríguez, Oswaldo
Solís Sosa, Carlos
Valdez Alegría, Grace Elizabeth
Quenaya Rodríguez, Roberth Jonathan
Escalante Jibaja, Ricardo
Cevallos Pacheco, Carlos
Ibarra Lavado, Oscar
Bocanegra Becerra, Yuliana Libet
author_role author
author2 Solís Sosa, Carlos
Valdez Alegría, Grace Elizabeth
Quenaya Rodríguez, Roberth Jonathan
Escalante Jibaja, Ricardo
Cevallos Pacheco, Carlos
Ibarra Lavado, Oscar
Bocanegra Becerra, Yuliana Libet
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Pregnancy
Hydatidiform mole
Invasive
Fetus
topic Pregnancy
Hydatidiform mole
Invasive
Fetus
description We report the case of a pregnant woman referred to our hospital for suspected partial hydatidiform mole. Ultrasound images showed a normal fetus attached to a small placenta adjacent to a honeycomb-like tumor mass. Amniocentesis revealed a normal karyotype. Due to β-hCG values greater than 800 000 IU and a mass growth of 11% by magnetic resonance imaging, an ultrasound-guided percutaneous tumor biopsy was performed; it ruled out the possibility of choriocarcinoma. The patient had symptoms of hyperthyroidism that required treatment; when the β-HCG levels exceeded one million IU, a course of chemotherapy was prescribed. At 29 weeks, the patient started labor; a cesarean hysterectomy was performed, obtaining a live newborn with Apgar 5 and 7. The pathology report informed the placental mass as an invasive mole. According to our literature search, this is the first case report where an invasive mole coexisted with a healthy fetus. We highlight the importance of using all diagnostic and management tools necessary to achieve fetal viability, without increasing the maternal risk of complications.
publishDate 2020
dc.date.none.fl_str_mv 2020-06-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2253
10.31403/rpgo.v66i2253
url https://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2253
identifier_str_mv 10.31403/rpgo.v66i2253
dc.language.none.fl_str_mv spa
eng
language spa
eng
dc.relation.none.fl_str_mv https://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2253/pdf
https://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2253/pdf_1
dc.rights.none.fl_str_mv Derechos de autor 2020 Revista Peruana de Ginecología y Obstetricia
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Derechos de autor 2020 Revista Peruana de Ginecología y Obstetricia
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Sociedad Peruana de Obstetricia y Ginecología
publisher.none.fl_str_mv Sociedad Peruana de Obstetricia y Ginecología
dc.source.none.fl_str_mv The Peruvian Journal of Gynecology and Obstetrics ; Vol. 66 No. 2 (2020)
Revista Peruana de Ginecología y Obstetricia; Vol. 66 Núm. 2 (2020)
2304-5132
2304-5124
reponame:Revista Peruana de Ginecología y Obstetricia
instname:Sociedad Peruana de Obstetricia y Ginecología
instacron:SPOG
instname_str Sociedad Peruana de Obstetricia y Ginecología
instacron_str SPOG
institution SPOG
reponame_str Revista Peruana de Ginecología y Obstetricia
collection Revista Peruana de Ginecología y Obstetricia
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