Growing ovarian teratoma syndrome: Case report and literature review

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The growing teratoma syndrome (GTS) is a rare condition in which patients with germ cell tumors present an increase in tumor size or the appearance of new lesions, during or after chemotherapy. The hallmark of this tumor is the unique presence of mature teratoma components, as well as tumor marker v...

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Autores: Alzamora, Maria Claudia, Portugal, Karem, Ortiz, Nazario, Lugon, Julia, Sinchi Roca, Tania, Diaz, Niccole, Venegas, Gino
Formato: artículo
Fecha de Publicación:2020
Institución:Sociedad Peruana de Obstetricia y Ginecología
Repositorio:Revista Peruana de Ginecología y Obstetricia
Lenguaje:español
inglés
OAI Identifier:oai:ginecologiayobstetricia.pe:article/2294
Enlace del recurso:https://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2294
Nivel de acceso:acceso abierto
Materia:Neoplasm
Germ Cell
Embryonal cell
Teratoma
Peru
Neoplasia
Células germinales
Células embrionarias
Perú
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spelling Growing ovarian teratoma syndrome: Case report and literature reviewSíndrome de teratoma creciente: reporte de caso y revisión de la literaturaAlzamora, Maria ClaudiaPortugal, KaremOrtiz, NazarioLugon, JuliaSinchi Roca, TaniaDiaz, NiccoleVenegas, GinoNeoplasmGerm CellEmbryonal cellTeratomaPeruNeoplasiaCélulas germinalesCélulas embrionariasTeratomaPerúThe growing teratoma syndrome (GTS) is a rare condition in which patients with germ cell tumors present an increase in tumor size or the appearance of new lesions, during or after chemotherapy. The hallmark of this tumor is the unique presence of mature teratoma components, as well as tumor marker values that become negative with chemotherapy, and remain low thereafter. We report the case of a 28-yearold female who presented a mixed germ cell tumor of the ovary, for which she underwent surgery and subsequent chemotherapy. Later, she developed multiple pelvic tumors that corresponded to mature teratoma. It was crucial in this patient to identify the syndrome to avoid additional treatment with chemotherapy.El síndrome de teratoma creciente (STC) es una condición infrecuente en la que se evidencia aumento de tamaño de los tumores de células germinales o la aparición de nuevas lesiones, durante o después del tratamiento con quimioterapia. Lo más característico de este tumor es la presencia exclusiva de componentes de teratoma maduro, así como valores de marcadores tumorales que negativizan durante la quimioterapia, y se mantienen negativos durante el seguimiento. Se presenta el caso de una mujer de 28 años con un tumor de ovario de células germinales mixtas sometida a cirugía y luego quimioterapia. Durante el seguimiento, desarrolló múltiples tumores pélvicos que correspondieron a teratomas maduros. En esta paciente, fue crucial identificar el síndrome de teratoma creciente para evitar tratamiento adicional con quimioterapia.Sociedad Peruana de Obstetricia y Ginecología2020-12-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://ginecologiayobstetricia.pe/index.php/RPGO/article/view/229410.31403/rpgo.v66i2294The Peruvian Journal of Gynecology and Obstetrics ; Vol. 66 No. 4 (2020)Revista Peruana de Ginecología y Obstetricia; Vol. 66 Núm. 4 (2020)2304-51322304-5124reponame:Revista Peruana de Ginecología y Obstetriciainstname:Sociedad Peruana de Obstetricia y Ginecologíainstacron:SPOGspaenghttps://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2294/pdf_1https://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2294/pdfDerechos de autor 2020 Revista Peruana de Ginecología y Obstetriciainfo:eu-repo/semantics/openAccessoai:ginecologiayobstetricia.pe:article/22942026-01-12T16:26:52Z
dc.title.none.fl_str_mv Growing ovarian teratoma syndrome: Case report and literature review
Síndrome de teratoma creciente: reporte de caso y revisión de la literatura
title Growing ovarian teratoma syndrome: Case report and literature review
spellingShingle Growing ovarian teratoma syndrome: Case report and literature review
Alzamora, Maria Claudia
Neoplasm
Germ Cell
Embryonal cell
Teratoma
Peru
Neoplasia
Células germinales
Células embrionarias
Teratoma
Perú
title_short Growing ovarian teratoma syndrome: Case report and literature review
title_full Growing ovarian teratoma syndrome: Case report and literature review
title_fullStr Growing ovarian teratoma syndrome: Case report and literature review
title_full_unstemmed Growing ovarian teratoma syndrome: Case report and literature review
title_sort Growing ovarian teratoma syndrome: Case report and literature review
dc.creator.none.fl_str_mv Alzamora, Maria Claudia
Portugal, Karem
Ortiz, Nazario
Lugon, Julia
Sinchi Roca, Tania
Diaz, Niccole
Venegas, Gino
author Alzamora, Maria Claudia
author_facet Alzamora, Maria Claudia
Portugal, Karem
Ortiz, Nazario
Lugon, Julia
Sinchi Roca, Tania
Diaz, Niccole
Venegas, Gino
author_role author
author2 Portugal, Karem
Ortiz, Nazario
Lugon, Julia
Sinchi Roca, Tania
Diaz, Niccole
Venegas, Gino
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Neoplasm
Germ Cell
Embryonal cell
Teratoma
Peru
Neoplasia
Células germinales
Células embrionarias
Teratoma
Perú
topic Neoplasm
Germ Cell
Embryonal cell
Teratoma
Peru
Neoplasia
Células germinales
Células embrionarias
Teratoma
Perú
description The growing teratoma syndrome (GTS) is a rare condition in which patients with germ cell tumors present an increase in tumor size or the appearance of new lesions, during or after chemotherapy. The hallmark of this tumor is the unique presence of mature teratoma components, as well as tumor marker values that become negative with chemotherapy, and remain low thereafter. We report the case of a 28-yearold female who presented a mixed germ cell tumor of the ovary, for which she underwent surgery and subsequent chemotherapy. Later, she developed multiple pelvic tumors that corresponded to mature teratoma. It was crucial in this patient to identify the syndrome to avoid additional treatment with chemotherapy.
publishDate 2020
dc.date.none.fl_str_mv 2020-12-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2294
10.31403/rpgo.v66i2294
url https://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2294
identifier_str_mv 10.31403/rpgo.v66i2294
dc.language.none.fl_str_mv spa
eng
language spa
eng
dc.relation.none.fl_str_mv https://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2294/pdf_1
https://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2294/pdf
dc.rights.none.fl_str_mv Derechos de autor 2020 Revista Peruana de Ginecología y Obstetricia
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Derechos de autor 2020 Revista Peruana de Ginecología y Obstetricia
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Sociedad Peruana de Obstetricia y Ginecología
publisher.none.fl_str_mv Sociedad Peruana de Obstetricia y Ginecología
dc.source.none.fl_str_mv The Peruvian Journal of Gynecology and Obstetrics ; Vol. 66 No. 4 (2020)
Revista Peruana de Ginecología y Obstetricia; Vol. 66 Núm. 4 (2020)
2304-5132
2304-5124
reponame:Revista Peruana de Ginecología y Obstetricia
instname:Sociedad Peruana de Obstetricia y Ginecología
instacron:SPOG
instname_str Sociedad Peruana de Obstetricia y Ginecología
instacron_str SPOG
institution SPOG
reponame_str Revista Peruana de Ginecología y Obstetricia
collection Revista Peruana de Ginecología y Obstetricia
repository.name.fl_str_mv
repository.mail.fl_str_mv
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