Clomiphene citrate in infertile women with ovulatory dysfunction

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Retrospective study in Infertility Clinic Loayza Hospital in Lima, between January 1980 and December 1991. They include 56 infertile ovulatory dysfunction treated with clomiphene citrate for a total of 197 cycles. Thirty patients had chronic anovulation or oligo-ovulation, and 26 patients with lutea...

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Detalles Bibliográficos
Autores: Jefferson Cortéz, Luz, Rechkemmer Prieto, Adolfo, Jiménez Vargas Machuca, Hugo
Formato: artículo
Fecha de Publicación:2015
Institución:Sociedad Peruana de Obstetricia y Ginecología
Repositorio:Revista Peruana de Ginecología y Obstetricia
Lenguaje:español
OAI Identifier:oai:ojs.pkp.sfu.ca:article/1350
Enlace del recurso:http://51.222.106.123/index.php/RPGO/article/view/1350
Nivel de acceso:acceso abierto
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spelling Clomiphene citrate in infertile women with ovulatory dysfunctionCitrato de clomifeno en mujeres infértiles con disfunción ovulatoriaJefferson Cortéz, LuzRechkemmer Prieto, AdolfoJiménez Vargas Machuca, HugoRetrospective study in Infertility Clinic Loayza Hospital in Lima, between January 1980 and December 1991. They include 56 infertile ovulatory dysfunction treated with clomiphene citrate for a total of 197 cycles. Thirty patients had chronic anovulation or oligo-ovulation, and 26 patients with luteal phase defect, in 83% of the first group of patients it was possible to induce ovulation, pregnancy rate being 29%. Most patients studied had peritoneal tubi factor associated with ovulatory dysfunction, factor associated with a poor prognosis for pregnancy (p <0.001). In 69% of pregnancies, these were achieved during the first three months of treatment, the required dose being 50 to 100 mg / day in 94% of cases. There were no multiple pregnancies and 1.6% of patients presented clinical data cycles of mild ovarian hyperstimulation.Estudio retrospectivo realizado en el Consultorio de Infertilidad del Hospital Loayza de Lima, entre enero de 1980 y diciembre de 1991. Se incluyen 56 infértiles con disfunción ovulatoria tratadas con citrato de clomifeno durante un total de 197 ciclos. Treinta pacientes presentaron anovulación crónica u oligo-ovulación, y 26 pacientes defecto de fase lútea, en el 83% del primer grupo de pacientes se logró inducir ovulación, siendo la tasa de embarazos de 29%. La mayor parte de pacientes estudiadas tenía factor tubi peritoneal asociado a la disfunción ovulatoria, factor que se asoció a un mal pronóstico para embarazo (p<0.001). En el 69% de embarazos, éstos se lograron durante los tres primeros meses de tratamiento, siendo la dosis necesaria de 50 a 100 mg/día en el 94% de los casos. No existieron embarazos múltiples y el 1.6% de los ciclos tratados presentó datos clínicos de hiperestimulación ovárica leve.Sociedad Peruana de Obstetricia y Ginecología2015-07-14info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://51.222.106.123/index.php/RPGO/article/view/1350The Peruvian Journal of Gynecology and Obstetrics ; Vol. 39 No. 14 (1993); 30-33Revista Peruana de Ginecología y Obstetricia; Vol. 39 Núm. 14 (1993); 30-332304-51322304-5124reponame:Revista Peruana de Ginecología y Obstetriciainstname:Sociedad Peruana de Obstetricia y Ginecologíainstacron:SPOGspahttp://51.222.106.123/index.php/RPGO/article/view/1350/1302info:eu-repo/semantics/openAccessoai:ojs.pkp.sfu.ca:article/13502015-07-27T18:49:53Z
dc.title.none.fl_str_mv Clomiphene citrate in infertile women with ovulatory dysfunction
Citrato de clomifeno en mujeres infértiles con disfunción ovulatoria
title Clomiphene citrate in infertile women with ovulatory dysfunction
spellingShingle Clomiphene citrate in infertile women with ovulatory dysfunction
Jefferson Cortéz, Luz
title_short Clomiphene citrate in infertile women with ovulatory dysfunction
title_full Clomiphene citrate in infertile women with ovulatory dysfunction
title_fullStr Clomiphene citrate in infertile women with ovulatory dysfunction
title_full_unstemmed Clomiphene citrate in infertile women with ovulatory dysfunction
title_sort Clomiphene citrate in infertile women with ovulatory dysfunction
dc.creator.none.fl_str_mv Jefferson Cortéz, Luz
Rechkemmer Prieto, Adolfo
Jiménez Vargas Machuca, Hugo
author Jefferson Cortéz, Luz
author_facet Jefferson Cortéz, Luz
Rechkemmer Prieto, Adolfo
Jiménez Vargas Machuca, Hugo
author_role author
author2 Rechkemmer Prieto, Adolfo
Jiménez Vargas Machuca, Hugo
author2_role author
author
description Retrospective study in Infertility Clinic Loayza Hospital in Lima, between January 1980 and December 1991. They include 56 infertile ovulatory dysfunction treated with clomiphene citrate for a total of 197 cycles. Thirty patients had chronic anovulation or oligo-ovulation, and 26 patients with luteal phase defect, in 83% of the first group of patients it was possible to induce ovulation, pregnancy rate being 29%. Most patients studied had peritoneal tubi factor associated with ovulatory dysfunction, factor associated with a poor prognosis for pregnancy (p <0.001). In 69% of pregnancies, these were achieved during the first three months of treatment, the required dose being 50 to 100 mg / day in 94% of cases. There were no multiple pregnancies and 1.6% of patients presented clinical data cycles of mild ovarian hyperstimulation.
publishDate 2015
dc.date.none.fl_str_mv 2015-07-14
dc.type.none.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.none.fl_str_mv http://51.222.106.123/index.php/RPGO/article/view/1350
url http://51.222.106.123/index.php/RPGO/article/view/1350
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv http://51.222.106.123/index.php/RPGO/article/view/1350/1302
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Sociedad Peruana de Obstetricia y Ginecología
publisher.none.fl_str_mv Sociedad Peruana de Obstetricia y Ginecología
dc.source.none.fl_str_mv The Peruvian Journal of Gynecology and Obstetrics ; Vol. 39 No. 14 (1993); 30-33
Revista Peruana de Ginecología y Obstetricia; Vol. 39 Núm. 14 (1993); 30-33
2304-5132
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institution SPOG
reponame_str Revista Peruana de Ginecología y Obstetricia
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