The clinical importance of serrated lesions of the colorectum

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Colorectal cancer (CRC) is the third most common cancer in the world. Fortunately, it is also proven to be one of the most preventable cancers, in large part due to the utilization of CRC screening. Historically, it was believed that the adenomatous polyp was the only precursor to carcinoma of the c...

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Detalles Bibliográficos
Autor: Burke, Carol
Formato: artículo
Fecha de Publicación:2017
Institución:Sociedad de Gastroenterología del Perú
Repositorio:Revista de Gastroenterología del Perú
Lenguaje:español
OAI Identifier:oai:ojs.revistagastroperu.com:article/220
Enlace del recurso:http://www.revistagastroperu.com/index.php/rgp/article/view/220
Nivel de acceso:acceso abierto
Materia:Colorectal neoplasms
Colon
Rectum
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spelling The clinical importance of serrated lesions of the colorectumBurke, CarolColorectal neoplasmsColonRectumColorectal cancer (CRC) is the third most common cancer in the world. Fortunately, it is also proven to be one of the most preventable cancers, in large part due to the utilization of CRC screening. Historically, it was believed that the adenomatous polyp was the only precursor to carcinoma of the colorectum. Within the last decade, it has been shown that approximately 20-30% of sporadic colon cancers arise through a distinct molecular pathway called CpG Island Methylation (CIMP) which is due to widespread DNA methylation. There is strong evidence that serrated polyps are the precursor lesions for colon cancers arising through the CIMP pathway.Sociedad de Gastroenterología del Perú2017-08-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://www.revistagastroperu.com/index.php/rgp/article/view/22010.47892/rgp.2013.332.220Revista de Gastroenterología del Perú; 2013 Vol 33 (2); 147-511609-722X1022-5129reponame:Revista de Gastroenterología del Perúinstname:Sociedad de Gastroenterología del Perúinstacron:SOCIOGASTROspahttp://www.revistagastroperu.com/index.php/rgp/article/view/220/215Derechos de autor 2017 Revista de Gastroenterología del Perúinfo:eu-repo/semantics/openAccessoai:ojs.revistagastroperu.com:article/2202017-08-08T06:58:36Z
dc.title.none.fl_str_mv The clinical importance of serrated lesions of the colorectum
title The clinical importance of serrated lesions of the colorectum
spellingShingle The clinical importance of serrated lesions of the colorectum
Burke, Carol
Colorectal neoplasms
Colon
Rectum
title_short The clinical importance of serrated lesions of the colorectum
title_full The clinical importance of serrated lesions of the colorectum
title_fullStr The clinical importance of serrated lesions of the colorectum
title_full_unstemmed The clinical importance of serrated lesions of the colorectum
title_sort The clinical importance of serrated lesions of the colorectum
dc.creator.none.fl_str_mv Burke, Carol
author Burke, Carol
author_facet Burke, Carol
author_role author
dc.subject.none.fl_str_mv Colorectal neoplasms
Colon
Rectum
topic Colorectal neoplasms
Colon
Rectum
description Colorectal cancer (CRC) is the third most common cancer in the world. Fortunately, it is also proven to be one of the most preventable cancers, in large part due to the utilization of CRC screening. Historically, it was believed that the adenomatous polyp was the only precursor to carcinoma of the colorectum. Within the last decade, it has been shown that approximately 20-30% of sporadic colon cancers arise through a distinct molecular pathway called CpG Island Methylation (CIMP) which is due to widespread DNA methylation. There is strong evidence that serrated polyps are the precursor lesions for colon cancers arising through the CIMP pathway.
publishDate 2017
dc.date.none.fl_str_mv 2017-08-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://www.revistagastroperu.com/index.php/rgp/article/view/220
10.47892/rgp.2013.332.220
url http://www.revistagastroperu.com/index.php/rgp/article/view/220
identifier_str_mv 10.47892/rgp.2013.332.220
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv http://www.revistagastroperu.com/index.php/rgp/article/view/220/215
dc.rights.none.fl_str_mv Derechos de autor 2017 Revista de Gastroenterología del Perú
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Derechos de autor 2017 Revista de Gastroenterología del Perú
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedad de Gastroenterología del Perú
publisher.none.fl_str_mv Sociedad de Gastroenterología del Perú
dc.source.none.fl_str_mv Revista de Gastroenterología del Perú; 2013 Vol 33 (2); 147-51
1609-722X
1022-5129
reponame:Revista de Gastroenterología del Perú
instname:Sociedad de Gastroenterología del Perú
instacron:SOCIOGASTRO
instname_str Sociedad de Gastroenterología del Perú
instacron_str SOCIOGASTRO
institution SOCIOGASTRO
reponame_str Revista de Gastroenterología del Perú
collection Revista de Gastroenterología del Perú
repository.name.fl_str_mv
repository.mail.fl_str_mv
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The clinical importance of serrated lesions of the colorectum
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