Lymphocytic esophagitis as a cause of dysphagia: a case report and brief literature review

• Autores: Perez-Valenzuela, Javier, Barrera, Manuel, Vergara, María Francisca, Chahuán, Javier
• Formato: artículo
• Fecha de Publicación: 2026
• Institución: Sociedad de Gastroenterología del Perú
• Repositorio: Revista de Gastroenterología del Perú
• Lenguaje: español
• OAI Identifier: oai:ojs.revistagastroperu.com:article/2089
• Enlace del recurso: https://revistagastroperu.com/index.php/rgp/article/view/2089
• Nivel de acceso: acceso abierto
• Materia: Disfagia; Esofagitis; Endoscopía; Dysphagia; Esophagitis; Endoscopy

Lymphocytic esophagitis (LyE) is a chronic inflammatory condition of the esophagus with a prevalence of ~0.1% among esophageal biopsies. The main clinical manifestations are dysphagia, heartburn, and chest pain; some endoscopic findings includes rings, strictures, and furrows. A 63-year-old woman with Sjögren syndrome and treated hypothyroidism presented with a 1-year history of progressive solid-food dysphagia and 4-kg weight loss. Endoscopy and a barium esophagogram revealed a proximal esophageal web, which was treated with endoscopic dilation. A follow-up esophagogastroduodenoscopy showed esophageal rings and luminal narrowing. Biopsies confirmed LyE. She was treated with esomeprazole with good clinical response. LyE is a recently described entity in which clinicopathologic correlations are not always straightforward. Given overlap in symptoms and endoscopic features, eosinophilic esophagitis is the principal differential diagnosis. Management options include proton-pump inhibitors, swallowed topical corticosteroids, and esophageal dilation for fixed strictures. Clear, evidence-based clinical guidelines are still lacking.