Treatment of Staphylococcus aureus keratitis with 0.2% topical linezolid

• Autor: Lavado Landeo, Lincoln
• Formato: artículo
• Fecha de Publicación: 2015
• Institución: Universidad de San Martín de Porres
• Repositorio: Horizonte médico
• Lenguaje: español
• OAI Identifier: oai:horizontemedico.usmp.edu.pe:article/301
• Enlace del recurso: https://www.horizontemedico.usmp.edu.pe/index.php/horizontemed/article/view/301
• Nivel de acceso: acceso abierto
• Materia: Bacterial keratitis; Staphylococcus aureus; Vancomycin; Linezolid; Queratitis bacteriana; Vancomicina

Objective: To reportthe use of 0.2% topical linezolid in the treatment of Staphylococcus aureuskeratitis with successful results. Material and Methods: All cases were viewed in Centro Vision, here they underwent a complete ophthalmic examination and were diagnosed with Staphylococcus aureus keratitis based on a microbiological study. In both cases we began with the gold standard therapy based on fortified topical drops of vancomycin and an aminoglycoside. Due to ineffective action and/or poor tolerance of vancomycin, we decided to use topical linezolid. Results: Two female patients with Staphylococcus aureus keratitis received ocular 0.2% topical linezolid every hour. In both cases we saw a marked clinical improvement and a good tolerance to this antibiotic. Conclusion: 0.2% Topical linezolid is an effective and well tolerated antibiotic when used in the treatment of Staphylococcus aureus keratitis. It is more comfortable and less toxic than topical vancomycin.