Harlequin color change in a newborn who was positive for COVID-19: report of a case

• Autores: Pinel-Guzmán, Esther, Martínez-Fernandez, Julian, Pinel-Dubón, Rafael, Gradis-Santos, Olman, Santamaría-Vásquez, Mario
• Formato: artículo
• Fecha de Publicación: 2023
• Institución: Colegio Médico del Perú
• Repositorio: Acta Médica Peruana
• Lenguaje: inglés; español
• OAI Identifier: oai:amp.cmp.org.pe:article/2177
• Enlace del recurso: https://amp.cmp.org.pe/index.php/AMP/article/view/2177
• Nivel de acceso: acceso abierto
• Materia: Infecciones por Coronavirus; COVID-19; Recién Nacido; Síndrome de Arlequín; Pediatría; Manifestaciones cutáneas; Coronavirus Infections; Newborn; Harlequin syndrome; Pediatrics; Skin Manifestations

Harlequin color change is a benign, idiopathic, self-limiting disorder characterized by the appearance of skin divided into two distinctly colored areas. Its etiology is unknown but thought to be caused by immaturity of hypothalamic regulation of peripheral vascular tone. COVID-19 infection in neonates is infrequent and rarely symptomatic, with only a few cases described in the literature. In isolation, both conditions have a low incidence. It is the first case reported in the world literature of harlequin color change in a newborn who tested positive for COVID-19. There isn’t a single publication that links harlequin color change to COVID-19.