Genomics and proteomics: one further step

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The development of genomics and proteomics depends on fundamental discoveries that resulted in new paradigms, theories and technologies, that have drastically changed the focus of medical sciences. The discovery of the structure of DNA and the basic functions of replication, transcription and transl...

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Detalles Bibliográficos
Autores: Aldecoa Bedoya, Franklin, Battilana Guanilo, Carlos
Formato: artículo
Fecha de Publicación:2024
Institución:Colegio Médico del Perú
Repositorio:Acta Médica Peruana
Lenguaje:español
OAI Identifier:oai:ojs.pkp.sfu.ca:article/1195
Enlace del recurso:https://amp.cmp.org.pe/index.php/AMP/article/view/1195
Nivel de acceso:acceso abierto
Materia:Porteomic
Genomic
Genotherapy
Molecular biology
Cloning
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spelling Genomics and proteomics: one further stepGenómica y proteómica: Un paso másAldecoa Bedoya, Franklin Battilana Guanilo, Carlos PorteomicGenomicGenotherapyMolecular biologyCloningThe development of genomics and proteomics depends on fundamental discoveries that resulted in new paradigms, theories and technologies, that have drastically changed the focus of medical sciences. The discovery of the structure of DNA and the basic functions of replication, transcription and translation, associated to the manipulation of cellular genetic material through restriction enzymes, ligases, polymerases, nucleotide base sequences, etc., lead us to genetic engineering, the disclosure of the human genome, the creation of new tools for the study of diseases and diagnosis, such as PCR (Polymerase Chain Reaction), microarray technology, and the better understanding of the behavior of our organism in relation to medication (pharmacogenomics). Now we have a greater challenge: to improve our understanding of the behavior of proteins as basic elements, the machinery through which DNA generates life. These new concepts carry new responsibilities, bring up ethical and moral problems and the need for appropriate legislation for their development.El desarrollo de la genómica y proteómica descansan sobre los descubrimientos fundamentales que constituyen hitos históricos sin los cuales no hubiera sido posible el hallazgo de nuevos paradigmas, teorías, tecnología, que han cambiado drásticamente el enfoque de la ciencia médica. El descubrimiento de la estructura del ADN y sus funciones básicas: replicación, transcripción y traducción, asociadas a la manipulación del material genético celular a través de las enzimas de restricción, ligasas, polimerasas, secuenciación de las bases nucleotídicas, nos llevaron a la ingeniería genética, el develamiento del genoma humano, la creación de nuevas herramientas para el estudio y diagnostico de las enfermedades, como el PCR (reacción en cadena de la polimerasa), microarray, y al mejor entendimiento acerca del comportamiento de nuestro organismo frente a los medicamentos (farmacogenómica). Ahora nos toca un reto superior: entender mejor el comportamiento de las proteínas como elementos básicos de vida, el alfabeto a través del cual el DNA genera vida. Estos nuevos conceptos traen consigo nuevas responsabilidades, problemas éticos y morales y obviamente la necesidad de una nueva legislación para este desarrollo.Colegio Médico del Perú2024-05-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://amp.cmp.org.pe/index.php/AMP/article/view/1195ACTA MEDICA PERUANA; Vol 23 No 3 (2006); 185 - 192ACTA MEDICA PERUANA; Vol. 23 Núm. 3 (2006); 185 - 1921728-59171018-8800reponame:Acta Médica Peruanainstname:Colegio Médico del Perúinstacron:CMPspahttps://amp.cmp.org.pe/index.php/AMP/article/view/1195/670Copyright (c) 2020 ACTA MEDICA PERUANAinfo:eu-repo/semantics/openAccessoai:ojs.pkp.sfu.ca:article/11952024-05-23T07:18:27Z
dc.title.none.fl_str_mv Genomics and proteomics: one further step
Genómica y proteómica: Un paso más
title Genomics and proteomics: one further step
spellingShingle Genomics and proteomics: one further step
Aldecoa Bedoya, Franklin
Porteomic
Genomic
Genotherapy
Molecular biology
Cloning
title_short Genomics and proteomics: one further step
title_full Genomics and proteomics: one further step
title_fullStr Genomics and proteomics: one further step
title_full_unstemmed Genomics and proteomics: one further step
title_sort Genomics and proteomics: one further step
dc.creator.none.fl_str_mv Aldecoa Bedoya, Franklin
Battilana Guanilo, Carlos
author Aldecoa Bedoya, Franklin
author_facet Aldecoa Bedoya, Franklin
Battilana Guanilo, Carlos
author_role author
author2 Battilana Guanilo, Carlos
author2_role author
dc.subject.none.fl_str_mv Porteomic
Genomic
Genotherapy
Molecular biology
Cloning
topic Porteomic
Genomic
Genotherapy
Molecular biology
Cloning
description The development of genomics and proteomics depends on fundamental discoveries that resulted in new paradigms, theories and technologies, that have drastically changed the focus of medical sciences. The discovery of the structure of DNA and the basic functions of replication, transcription and translation, associated to the manipulation of cellular genetic material through restriction enzymes, ligases, polymerases, nucleotide base sequences, etc., lead us to genetic engineering, the disclosure of the human genome, the creation of new tools for the study of diseases and diagnosis, such as PCR (Polymerase Chain Reaction), microarray technology, and the better understanding of the behavior of our organism in relation to medication (pharmacogenomics). Now we have a greater challenge: to improve our understanding of the behavior of proteins as basic elements, the machinery through which DNA generates life. These new concepts carry new responsibilities, bring up ethical and moral problems and the need for appropriate legislation for their development.
publishDate 2024
dc.date.none.fl_str_mv 2024-05-22
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://amp.cmp.org.pe/index.php/AMP/article/view/1195
url https://amp.cmp.org.pe/index.php/AMP/article/view/1195
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://amp.cmp.org.pe/index.php/AMP/article/view/1195/670
dc.rights.none.fl_str_mv Copyright (c) 2020 ACTA MEDICA PERUANA
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2020 ACTA MEDICA PERUANA
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Colegio Médico del Perú
publisher.none.fl_str_mv Colegio Médico del Perú
dc.source.none.fl_str_mv ACTA MEDICA PERUANA; Vol 23 No 3 (2006); 185 - 192
ACTA MEDICA PERUANA; Vol. 23 Núm. 3 (2006); 185 - 192
1728-5917
1018-8800
reponame:Acta Médica Peruana
instname:Colegio Médico del Perú
instacron:CMP
instname_str Colegio Médico del Perú
instacron_str CMP
institution CMP
reponame_str Acta Médica Peruana
collection Acta Médica Peruana
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 13.924177
Genomics and proteomics: one further step
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