Low-grade multicentric glioma: a rare entity

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Multiple gliomas (multifocal and multicentric) are rare in low-grade gliomas. In multicentric gliomas, their etiology is poorly understood, and their management is controversial. A 27-year-old female patient, with two lesions compatible with low-grade glioma, confirmed by pathological study, for whi...

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Detalles Bibliográficos
Autores: Vargas-Urbina, John, Martinez-Silva, Raúl, Rojas-Panta, Giuseppe, Flores- Castillo, Jerson, Anicama Lima, William
Formato: artículo
Fecha de Publicación:2024
Institución:Colegio Médico del Perú
Repositorio:Acta Médica Peruana
Lenguaje:español
OAI Identifier:oai:ojs.pkp.sfu.ca:article/2907
Enlace del recurso:https://amp.cmp.org.pe/index.php/AMP/article/view/2907
Nivel de acceso:acceso abierto
Materia:Glioma
Astrocytoma
Tumors, Glial Cell
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spelling Low-grade multicentric glioma: a rare entityGlioma de bajo grado multicéntrico: una entidad infrecuenteVargas-Urbina, JohnMartinez-Silva, RaúlRojas-Panta, GiuseppeFlores- Castillo, JersonAnicama Lima, WilliamGliomaAstrocytomaTumors, Glial Cell Multiple gliomas (multifocal and multicentric) are rare in low-grade gliomas. In multicentric gliomas, their etiology is poorly understood, and their management is controversial. A 27-year-old female patient, with two lesions compatible with low-grade glioma, confirmed by pathological study, for which; she received chemotherapy and radiotherapy, maintaining stable disease after one year of follow-up; she could not undergo surgery because the lesions were located in eloquent areas. For this type of patient, the standard of care is surgery whenever feasible based on eloquence and vascular involvement, followed by chemotherapy and radiotherapy like treatment given in single gliomas. Low-grade multicentric gliomas are a rare pathology that must be managed by a multidisciplinary team where surgery is the standard of care whenever feasible, followed by chemotherapy and radiotherapy. Los gliomas múltiples (multifocales y multicéntricos) son poco frecuentes en los gliomas de bajo grado. La etiología de los gliomas multicéntricos es poco conocida y su manejo es controversial. Se presenta el caso de una paciente de 27 años, con dos lesiones compatibles imagenológicamente con glioma de bajo grado, confirmado por estudio anatomopatológico; recibe manejo con quimioterapia y radioterapia manteniéndose la enfermedad estable a un año de seguimiento; no pudo ser sometida a cirugía debido a que las lesiones se encontraban en áreas elocuentes. Para este tipo de pacientes el tratamiento de elección es la cirugía, siempre que sea factible, según elocuencia y compromiso vascular, seguido de esquemas de quimioterapia y radioterapia, según el esquema que se da en gliomas únicos. Por ello, los gliomas multicéntricos de bajo grado son una patología rara que debe ser manejado por un equipo multidisciplinario donde la cirugía es el tratamiento de elección, siempre que sea factible, seguido de quimioterapia y radioterapia. Colegio Médico del Perú2024-06-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/htmltext/xmlhttps://amp.cmp.org.pe/index.php/AMP/article/view/290710.35663/amp.2024.412.2907ACTA MEDICA PERUANA; Vol 41 No 2 (2024): April - June; 127-131ACTA MEDICA PERUANA; Vol. 41 Núm. 2 (2024): Abril - Junio; 127-1311728-59171018-8800reponame:Acta Médica Peruanainstname:Colegio Médico del Perúinstacron:CMPspahttps://amp.cmp.org.pe/index.php/AMP/article/view/2907/1640https://amp.cmp.org.pe/index.php/AMP/article/view/2907/1663https://amp.cmp.org.pe/index.php/AMP/article/view/2907/1664Copyright (c) 2024 ACTA MEDICA PERUANAinfo:eu-repo/semantics/openAccessoai:ojs.pkp.sfu.ca:article/29072024-11-18T07:47:15Z
dc.title.none.fl_str_mv Low-grade multicentric glioma: a rare entity
Glioma de bajo grado multicéntrico: una entidad infrecuente
title Low-grade multicentric glioma: a rare entity
spellingShingle Low-grade multicentric glioma: a rare entity
Vargas-Urbina, John
Glioma
Astrocytoma
Tumors, Glial Cell
title_short Low-grade multicentric glioma: a rare entity
title_full Low-grade multicentric glioma: a rare entity
title_fullStr Low-grade multicentric glioma: a rare entity
title_full_unstemmed Low-grade multicentric glioma: a rare entity
title_sort Low-grade multicentric glioma: a rare entity
dc.creator.none.fl_str_mv Vargas-Urbina, John
Martinez-Silva, Raúl
Rojas-Panta, Giuseppe
Flores- Castillo, Jerson
Anicama Lima, William
author Vargas-Urbina, John
author_facet Vargas-Urbina, John
Martinez-Silva, Raúl
Rojas-Panta, Giuseppe
Flores- Castillo, Jerson
Anicama Lima, William
author_role author
author2 Martinez-Silva, Raúl
Rojas-Panta, Giuseppe
Flores- Castillo, Jerson
Anicama Lima, William
author2_role author
author
author
author
dc.subject.none.fl_str_mv Glioma
Astrocytoma
Tumors, Glial Cell
topic Glioma
Astrocytoma
Tumors, Glial Cell
description Multiple gliomas (multifocal and multicentric) are rare in low-grade gliomas. In multicentric gliomas, their etiology is poorly understood, and their management is controversial. A 27-year-old female patient, with two lesions compatible with low-grade glioma, confirmed by pathological study, for which; she received chemotherapy and radiotherapy, maintaining stable disease after one year of follow-up; she could not undergo surgery because the lesions were located in eloquent areas. For this type of patient, the standard of care is surgery whenever feasible based on eloquence and vascular involvement, followed by chemotherapy and radiotherapy like treatment given in single gliomas. Low-grade multicentric gliomas are a rare pathology that must be managed by a multidisciplinary team where surgery is the standard of care whenever feasible, followed by chemotherapy and radiotherapy.
publishDate 2024
dc.date.none.fl_str_mv 2024-06-30
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://amp.cmp.org.pe/index.php/AMP/article/view/2907
10.35663/amp.2024.412.2907
url https://amp.cmp.org.pe/index.php/AMP/article/view/2907
identifier_str_mv 10.35663/amp.2024.412.2907
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://amp.cmp.org.pe/index.php/AMP/article/view/2907/1640
https://amp.cmp.org.pe/index.php/AMP/article/view/2907/1663
https://amp.cmp.org.pe/index.php/AMP/article/view/2907/1664
dc.rights.none.fl_str_mv Copyright (c) 2024 ACTA MEDICA PERUANA
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2024 ACTA MEDICA PERUANA
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
text/html
text/xml
dc.publisher.none.fl_str_mv Colegio Médico del Perú
publisher.none.fl_str_mv Colegio Médico del Perú
dc.source.none.fl_str_mv ACTA MEDICA PERUANA; Vol 41 No 2 (2024): April - June; 127-131
ACTA MEDICA PERUANA; Vol. 41 Núm. 2 (2024): Abril - Junio; 127-131
1728-5917
1018-8800
reponame:Acta Médica Peruana
instname:Colegio Médico del Perú
instacron:CMP
instname_str Colegio Médico del Perú
instacron_str CMP
institution CMP
reponame_str Acta Médica Peruana
collection Acta Médica Peruana
repository.name.fl_str_mv
repository.mail.fl_str_mv
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