Vitamin D deficiency associated with hyperphosphatemia in children

• Autor: Virú-Loza, Manuel André
• Formato: artículo
• Fecha de Publicación: 2021
• Institución: Colegio Médico del Perú
• Repositorio: Acta Médica Peruana
• Lenguaje: español
• OAI Identifier: oai:ojs.pkp.sfu.ca:article/1909
• Enlace del recurso: https://amp.cmp.org.pe/index.php/AMP/article/view/1909
• Nivel de acceso: acceso abierto
• Materia: Vitamin D; Vitamin D Deficiency; Hyperphosphatemia; Rickets; Pseudohypoparathyroidism; Parathyroid Hormone; Hypocalcemia; Child

Children with vitamin D deficiency can have normal or high phosphorus despite having a high parathyroid hormone test (PTH). Pseudohypoparathyroidism (PHP) is characterized by hyperphosphatemia. The similarity that can occur between vitamin D deficiency associated with hyperphosphatemia and PHP makes it important to review case reports of vitamin D deficiency associated with hyperphosphatemia to understand why this association may occur and what is the relevance of studying the vitamin D level in children with suspected PHP. The aim of this review was to identify reports of children with vitamin D deficiency associated with hyperphosphatemia and to discuss the mechanisms of this association. Reports of 7 children cases were identified. Vitamin D deficiency could reduce the phosphaturic response to elevated PTH. It is concluded that it is important to rule out vitamin D deficiency in all children with suspected PHP