Asymptomatic Venous Thromboembolic Disease in a patient with Down syndrome: A case report and clinical presentation

• Autores: De-La-Cruz-Chuquilin, Enrique, Vásquez-Tirado, Gustavo, Liberato-Salinas, Yuri
• Formato: artículo
• Fecha de Publicación: 2021
• Institución: Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
• Repositorio: Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
• Lenguaje: español
• OAI Identifier: oai:cmhnaaa_ojs_cmhnaaa.cmhnaaa.org.pe:article/887
• Enlace del recurso: https://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/887
• Nivel de acceso: acceso abierto
• Materia: Tromboembolia pulmonar; Trombosis de Vena Profunda; síndrome de Down; Klebsiella oxytoca; adulto joven; Pulmonary Embolism; Venous Thrombosis; Down syndrome; young adult

Introduction: Vascular disorders are frequent in Down Syndrome (SD); however, it is unclear whether such patients are at increased risk for venous thromboembolic events, making this association rare. Clinical case: We report the case of a 27-year-old female patient with DS who presented a large central embolus in the pulmonary artery and its middle lobular branch on the right side; likewise, a thrombus in the femoral artery that almost completely blocked its diameter, whose presentation is asymptomatic; being diagnosed by CT Angiography and Doppler ultrasound accordingly. Enoxaparin and Warfarin were given as treatment, having a favorable evolution. Conclusion: Much attention should be paid to the correlation between venous thromboembolic disease and Down syndrome, and a wide effort should be made in its prevention, detection and treatment.