Nucleic acid detection using a universal electrochemical sensor for SNS differentiation

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Nucleic acid detection with high sensitivity and selectivity capabilities could aid in the diagnosis of varies diseases such as: infections, cancer, among others. Discrimination of a mismatch or single nucleotide substitution (SNS) is challenge due to a minimum pair to pair formation double strand n...

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Detalles Bibliográficos
Autores: Calvo-Marzal, Percy, Kolpashchikov y Cols., Dmitry M.
Formato: artículo
Fecha de Publicación:2018
Institución:Centro de Preparación para la Ciencia y Tecnología
Repositorio:ECIPERÚ
Lenguaje:español
OAI Identifier:oai:revistas.eciperu.net:article/101
Enlace del recurso:https://revistas.eciperu.net/index.php/ECIPERU/article/view/101
Nivel de acceso:acceso abierto
Materia:Nuclei acid
Single nucleotide substitution
infection
cancer
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spelling Nucleic acid detection using a universal electrochemical sensor for SNS differentiationCalvo-Marzal, PercyKolpashchikov y Cols., Dmitry M.Nuclei acidSingle nucleotide substitutioninfectioncancerNuclei acidSingle nucleotide substitutioninfectioncancerNucleic acid detection with high sensitivity and selectivity capabilities could aid in the diagnosis of varies diseases such as: infections, cancer, among others. Discrimination of a mismatch or single nucleotide substitution (SNS) is challenge due to a minimum pair to pair formation double strand needed to stabilize the structure. Here we present a new approach to atinge the needed stability by using additional segments strains to favored stabilization. The use of additional complementary strains facilitates the discrimination of a SNS in a cooperative way.Nucleic acid detection with high sensitivity and selectivity capabilities could aid in the diagnosis of varies diseases such as: infections, cancer, among others. Discrimination of a mismatch or single nucleotide substitution (SNS) is challenge due to a minimum pair to pair formation double strand needed to stabilize the structure. Here we present a new approach to atinge the needed stability by using additional segments strains to favored stabilization. The use of additional complementary strains facilitates the discrimination of a SNS in a cooperative way.Centro de Preparación para la Ciencia y Tecnología (Ceprecyt)2018-12-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistas.eciperu.net/index.php/ECIPERU/article/view/10110.33017/RevECIPeru2017.0008/Revista ECIPerú; Vol. 14 Núm. 2 (2017); 81813-0194reponame:ECIPERÚinstname:Centro de Preparación para la Ciencia y Tecnologíainstacron:CEPRECYTspahttps://revistas.eciperu.net/index.php/ECIPERU/article/view/101/99Derechos de autor 2017 Revista ECIPerúinfo:eu-repo/semantics/openAccessoai:revistas.eciperu.net:article/1012019-01-21T16:26:19Z
dc.title.none.fl_str_mv Nucleic acid detection using a universal electrochemical sensor for SNS differentiation
title Nucleic acid detection using a universal electrochemical sensor for SNS differentiation
spellingShingle Nucleic acid detection using a universal electrochemical sensor for SNS differentiation
Calvo-Marzal, Percy
Nuclei acid
Single nucleotide substitution
infection
cancer
Nuclei acid
Single nucleotide substitution
infection
cancer
title_short Nucleic acid detection using a universal electrochemical sensor for SNS differentiation
title_full Nucleic acid detection using a universal electrochemical sensor for SNS differentiation
title_fullStr Nucleic acid detection using a universal electrochemical sensor for SNS differentiation
title_full_unstemmed Nucleic acid detection using a universal electrochemical sensor for SNS differentiation
title_sort Nucleic acid detection using a universal electrochemical sensor for SNS differentiation
dc.creator.none.fl_str_mv Calvo-Marzal, Percy
Kolpashchikov y Cols., Dmitry M.
author Calvo-Marzal, Percy
author_facet Calvo-Marzal, Percy
Kolpashchikov y Cols., Dmitry M.
author_role author
author2 Kolpashchikov y Cols., Dmitry M.
author2_role author
dc.subject.none.fl_str_mv Nuclei acid
Single nucleotide substitution
infection
cancer
Nuclei acid
Single nucleotide substitution
infection
cancer
topic Nuclei acid
Single nucleotide substitution
infection
cancer
Nuclei acid
Single nucleotide substitution
infection
cancer
description Nucleic acid detection with high sensitivity and selectivity capabilities could aid in the diagnosis of varies diseases such as: infections, cancer, among others. Discrimination of a mismatch or single nucleotide substitution (SNS) is challenge due to a minimum pair to pair formation double strand needed to stabilize the structure. Here we present a new approach to atinge the needed stability by using additional segments strains to favored stabilization. The use of additional complementary strains facilitates the discrimination of a SNS in a cooperative way.
publishDate 2018
dc.date.none.fl_str_mv 2018-12-27
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistas.eciperu.net/index.php/ECIPERU/article/view/101
10.33017/RevECIPeru2017.0008/
url https://revistas.eciperu.net/index.php/ECIPERU/article/view/101
identifier_str_mv 10.33017/RevECIPeru2017.0008/
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistas.eciperu.net/index.php/ECIPERU/article/view/101/99
dc.rights.none.fl_str_mv Derechos de autor 2017 Revista ECIPerú
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Derechos de autor 2017 Revista ECIPerú
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Centro de Preparación para la Ciencia y Tecnología (Ceprecyt)
publisher.none.fl_str_mv Centro de Preparación para la Ciencia y Tecnología (Ceprecyt)
dc.source.none.fl_str_mv Revista ECIPerú; Vol. 14 Núm. 2 (2017); 8
1813-0194
reponame:ECIPERÚ
instname:Centro de Preparación para la Ciencia y Tecnología
instacron:CEPRECYT
instname_str Centro de Preparación para la Ciencia y Tecnología
instacron_str CEPRECYT
institution CEPRECYT
reponame_str ECIPERÚ
collection ECIPERÚ
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 13.394457
Nucleic acid detection using a universal electrochemical sensor for SNS differentiation
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