Improving equitable access to comprehensive care for people with advanced breast cancer: a global expert review and call-to-action for 2025–2035 (Goal 9)
Descripción del Articulo
Advanced breast cancer (ABC) remains an incurable yet treatable disease, requiring lifelong care. While treatment advancements have extended survival for many patients, access to these innovations is far from universal. There remains a critical need to ensure equitable access to proven and establish...
| Autores: | , , , , , , , , , , , |
|---|---|
| Formato: | artículo |
| Fecha de Publicación: | 2025 |
| Institución: | Instituto Nacional de Enfermedades Neoplásicas |
| Repositorio: | INEN-Institucional |
| Lenguaje: | inglés |
| OAI Identifier: | oai:repositorio.inen.sld.pe:20.500.14703/484 |
| Enlace del recurso: | https://doi.org/10.1016/j.breast.2025.104612 https://hdl.handle.net/20.500.14703/484 |
| Nivel de acceso: | acceso abierto |
| Materia: | Advanced breast cancer Healthcare disparities Global health equity Universal coverage Financial toxicity Out-of-pocket https://purl.org/pe-repo/ocde/ford#3.02.21 |
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Improving equitable access to comprehensive care for people with advanced breast cancer: a global expert review and call-to-action for 2025–2035 (Goal 9) |
| title |
Improving equitable access to comprehensive care for people with advanced breast cancer: a global expert review and call-to-action for 2025–2035 (Goal 9) |
| spellingShingle |
Improving equitable access to comprehensive care for people with advanced breast cancer: a global expert review and call-to-action for 2025–2035 (Goal 9) Eniu, Alexandru Advanced breast cancer Healthcare disparities Global health equity Universal coverage Financial toxicity Out-of-pocket https://purl.org/pe-repo/ocde/ford#3.02.21 |
| title_short |
Improving equitable access to comprehensive care for people with advanced breast cancer: a global expert review and call-to-action for 2025–2035 (Goal 9) |
| title_full |
Improving equitable access to comprehensive care for people with advanced breast cancer: a global expert review and call-to-action for 2025–2035 (Goal 9) |
| title_fullStr |
Improving equitable access to comprehensive care for people with advanced breast cancer: a global expert review and call-to-action for 2025–2035 (Goal 9) |
| title_full_unstemmed |
Improving equitable access to comprehensive care for people with advanced breast cancer: a global expert review and call-to-action for 2025–2035 (Goal 9) |
| title_sort |
Improving equitable access to comprehensive care for people with advanced breast cancer: a global expert review and call-to-action for 2025–2035 (Goal 9) |
| author |
Eniu, Alexandru |
| author_facet |
Eniu, Alexandru Chidebe, Runcie Vuylsteke, Peter Chavez-MacGregor, Mariana Penault-Llorca, Frederique Lopes, Gilberto Aapro , Matti Neciosup, Silvia Pillay, Nisha Lewis, Alexandra Attfield, Georgia Cardoso, Fatima |
| author_role |
author |
| author2 |
Chidebe, Runcie Vuylsteke, Peter Chavez-MacGregor, Mariana Penault-Llorca, Frederique Lopes, Gilberto Aapro , Matti Neciosup, Silvia Pillay, Nisha Lewis, Alexandra Attfield, Georgia Cardoso, Fatima |
| author2_role |
author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Eniu, Alexandru Chidebe, Runcie Vuylsteke, Peter Chavez-MacGregor, Mariana Penault-Llorca, Frederique Lopes, Gilberto Aapro , Matti Neciosup, Silvia Pillay, Nisha Lewis, Alexandra Attfield, Georgia Cardoso, Fatima |
| dc.subject.none.fl_str_mv |
Advanced breast cancer Healthcare disparities Global health equity Universal coverage Financial toxicity Out-of-pocket |
| topic |
Advanced breast cancer Healthcare disparities Global health equity Universal coverage Financial toxicity Out-of-pocket https://purl.org/pe-repo/ocde/ford#3.02.21 |
| dc.subject.ocde.none.fl_str_mv |
https://purl.org/pe-repo/ocde/ford#3.02.21 |
| description |
Advanced breast cancer (ABC) remains an incurable yet treatable disease, requiring lifelong care. While treatment advancements have extended survival for many patients, access to these innovations is far from universal. There remains a critical need to ensure equitable access to proven and established interventions for all individuals with ABC, while continuing to drive progress in care and survival outcomes. This manuscript assesses the evolving economic landscape for and access to comprehensive ABC care since 2015. It describes the persistent access barriers and inequities, and outlines recommendations for the ABC community over the next decade. It summarizes research conducted for the ABC Global Alliance’s Global Decade Report 2.0. The main findings are: a) Disparities in access to ABC care are widening globally; b) Variable access to diagnostic services delays timely and adequate ABC treatment; c) Infrastructure, supply, and reimbursement barriers hinder ABC treatment access; d) High out-of-pocket costs drive severe financial toxicity across all income settings; e) In low-income contexts, multi-stakeholder efforts are improving access to ABC care. The findings from the ABC Global Alliance’s Global Decade Report 2.0 have informed the development of a new ABC Global Charter. The ABC Global Charter 2.0 defines ten new achievable and measurable goals for the decade 2025–2035, aiming at improving the lives of people living with ABC worldwide. |
| publishDate |
2025 |
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2025-12-15T00:43:26Z |
| dc.date.available.none.fl_str_mv |
2025-12-15T00:43:26Z |
| dc.date.issued.fl_str_mv |
2025 |
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info:eu-repo/semantics/article |
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info:eu-repo/semantics/publishedVersion |
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article |
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https://doi.org/10.1016/j.breast.2025.104612 |
| dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/20.500.14703/484 |
| dc.identifier.journal.none.fl_str_mv |
The Breast |
| url |
https://doi.org/10.1016/j.breast.2025.104612 https://hdl.handle.net/20.500.14703/484 |
| identifier_str_mv |
The Breast |
| dc.language.iso.none.fl_str_mv |
eng |
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eng |
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info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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https://creativecommons.org/licenses/by/4.0/ |
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application/pdf |
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Elsevier |
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US |
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Elsevier |
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PublicationEniu, AlexandruChidebe, RuncieVuylsteke, PeterChavez-MacGregor, MarianaPenault-Llorca, FrederiqueLopes, GilbertoAapro , MattiNeciosup, SilviaPillay, NishaLewis, AlexandraAttfield, GeorgiaCardoso, Fatima2025-12-15T00:43:26Z2025-12-15T00:43:26Z2025https://doi.org/10.1016/j.breast.2025.104612https://hdl.handle.net/20.500.14703/484The BreastAdvanced breast cancer (ABC) remains an incurable yet treatable disease, requiring lifelong care. While treatment advancements have extended survival for many patients, access to these innovations is far from universal. There remains a critical need to ensure equitable access to proven and established interventions for all individuals with ABC, while continuing to drive progress in care and survival outcomes. This manuscript assesses the evolving economic landscape for and access to comprehensive ABC care since 2015. It describes the persistent access barriers and inequities, and outlines recommendations for the ABC community over the next decade. It summarizes research conducted for the ABC Global Alliance’s Global Decade Report 2.0. The main findings are: a) Disparities in access to ABC care are widening globally; b) Variable access to diagnostic services delays timely and adequate ABC treatment; c) Infrastructure, supply, and reimbursement barriers hinder ABC treatment access; d) High out-of-pocket costs drive severe financial toxicity across all income settings; e) In low-income contexts, multi-stakeholder efforts are improving access to ABC care. The findings from the ABC Global Alliance’s Global Decade Report 2.0 have informed the development of a new ABC Global Charter. The ABC Global Charter 2.0 defines ten new achievable and measurable goals for the decade 2025–2035, aiming at improving the lives of people living with ABC worldwide.application/pdfengElsevierUSinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/4.0/Advanced breast cancerHealthcare disparitiesGlobal health equityUniversal coverageFinancial toxicityOut-of-pockethttps://purl.org/pe-repo/ocde/ford#3.02.21Improving equitable access to comprehensive care for people with advanced breast cancer: a global expert review and call-to-action for 2025–2035 (Goal 9)info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionreponame:INEN-Institucionalinstname:Instituto Nacional de Enfermedades Neoplásicasinstacron:INENCC-LICENSElicense_rdforg.dspace.license.CreativeCommonsapplication/rdf+xml; charset=utf-8905https://repositorio.inen.sld.pe/backend/api/core/bitstreams/96f21308-38a0-4532-9af0-1ade2569a55c/download1f14487299a8a795dc379bc1df9968a0MD51falseAnonymousREADLICENSElicense.txtWritten by org.dspace.content.LicenseUtilstext/plain; charset=utf-81748https://repositorio.inen.sld.pe/backend/api/core/bitstreams/b95b6c76-08ca-42b8-baf5-55aa0c414460/downloadbb9bdc0b3349e4284e09149f943790b4MD52falseAnonymousREADORIGINALDICIEMBRE 2 2025.pdfDICIEMBRE 2 2025.pdfapplication/pdf1022470https://repositorio.inen.sld.pe/backend/api/core/bitstreams/180d2cb5-7a00-4789-935e-ea9334a3ac2b/download2a8bfafa7e3946758722539d6bfddbf6MD53trueAnonymousREADTEXTDICIEMBRE 2 2025.pdf.txtWritten by FormatFilter org.dspace.app.mediafilter.TikaTextExtractionFilter on 2026-01-19T08:01:22Z (GMT).Extracted texttext/plain64395https://repositorio.inen.sld.pe/backend/api/core/bitstreams/c72712c4-d3ea-4f6c-afed-4fc8f545a7d6/download28b2dd19655b3ceabaf98b219628b203MD54falseAnonymousREADTHUMBNAILDICIEMBRE 2 2025.pdf.jpgWritten by FormatFilter org.dspace.app.mediafilter.PDFBoxThumbnail on 2026-01-19T08:01:22Z (GMT).Generated Thumbnailimage/jpeg34687https://repositorio.inen.sld.pe/backend/api/core/bitstreams/9b858680-a270-430b-9a21-b99a15404124/downloadf6cf82b2f7c2811f1a4476857621f9f7MD55falseAnonymousREAD20.500.14703/484oai:repositorio.inen.sld.pe:20.500.14703/4842026-02-17T13:59:32.151Zhttps://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessopen.accesshttps://repositorio.inen.sld.peRepositorio del Instituto Nacional de Enfermedades Neoplásicasrepositorio@inen.sld.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 |
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Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).