Cáncer, quimioterapia y un corazón roto. Reporte de un caso de cardiomiopatía de Takotsubo asociada a quimioterapia

• Autores: Coca-Caycho, Tatiana G., Custodio-Sánche, Piero
• Formato: artículo
• Fecha de Publicación: 2019
• Institución: Seguro Social de Salud
• Repositorio: ESSALUD-Institucional
• Lenguaje: español
• OAI Identifier: oai:repositorio.essalud.gob.pe:20.500.12959/3789
• Enlace del recurso: https://hdl.handle.net/20.500.12959/3789; https://doi.org/10.35434/rcmhnaaa.2019.121.484
• Nivel de acceso: acceso abierto
• Materia: Takotsubo; Cáncer; Quimioterapia; Chemotherapy; Cancer; https://purl.org/pe-repo/ocde/ford#3.02.21

Introduction: The link between chemotherapy and Takotsubo cardiomyopathy has become increasingly recognized in recent years, although causality remains to be established and the mechanism of action is not yet fully understood. Case Report:Here we present the case of a patient with Multiple Myeloma, that after of cytotoxictreatmentwithcyclophosphamideand thalidomide, developed coronary acute syndrome. She wentontohavecoronaryangiographythat demonstratedunobstructedcoronaryarteriesand Apicalballooning,consistentwithTakotsubo Cardiomyopathy.Conclusion:Takotsubo cardiomyopathymayrepresentaformofcardiac dysfunction within the spectrum of chemotherapy-induced cardiac toxicity that differs from the more commoncumulative-dosingtoxicity.Giventhe increasing amount of case report, and the presence of recurrence after the re administration from the same chemotherapy agent; must be properly identified and avoid its use in high risk patient.