Immediate skin test reactivity to common aeroallergens in patients with respiratory allergies: A comparative analysis of allergen-induced skin reactions and their histamine controls
Descripción del Articulo
From the Department of Microbiology (Immunology Section) Uni-versidad Peruana Cayetano Heredia, Lima, Peru. Supported in part by a grant from Consejo de Ciencia y Tecnologia (CONCYTEC) of Peru.
| Autores: | , , |
|---|---|
| Formato: | artículo |
| Fecha de Publicación: | 1988 |
| Institución: | Consejo Nacional de Ciencia Tecnología e Innovación |
| Repositorio: | CONCYTEC-Institucional |
| Lenguaje: | inglés |
| OAI Identifier: | oai:repositorio.concytec.gob.pe:20.500.12390/803 |
| Enlace del recurso: | https://hdl.handle.net/20.500.12390/803 https://doi.org/10.1016/0091-6749(88)90882-2 |
| Nivel de acceso: | acceso abierto |
| Materia: | skin test allergen adolescent adult age aged child controlled study female human major clinical study male priority journal respiratory tract allergy sex difference Adolescent Adult Age Factors Aged Air Pollutants Allergens Child https://purl.org/pe-repo/ocde/ford#1.06.01 |
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CONC_d1021d4af842ca5619607a3f8319b0bf |
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oai:repositorio.concytec.gob.pe:20.500.12390/803 |
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CONC |
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CONCYTEC-Institucional |
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4689 |
| dc.title.none.fl_str_mv |
Immediate skin test reactivity to common aeroallergens in patients with respiratory allergies: A comparative analysis of allergen-induced skin reactions and their histamine controls |
| title |
Immediate skin test reactivity to common aeroallergens in patients with respiratory allergies: A comparative analysis of allergen-induced skin reactions and their histamine controls |
| spellingShingle |
Immediate skin test reactivity to common aeroallergens in patients with respiratory allergies: A comparative analysis of allergen-induced skin reactions and their histamine controls Lopez L.R. skin test allergen adolescent adult age aged child controlled study female human major clinical study male priority journal respiratory tract allergy sex difference Adolescent Adult Age Factors Aged Air Pollutants Allergens Child https://purl.org/pe-repo/ocde/ford#1.06.01 |
| title_short |
Immediate skin test reactivity to common aeroallergens in patients with respiratory allergies: A comparative analysis of allergen-induced skin reactions and their histamine controls |
| title_full |
Immediate skin test reactivity to common aeroallergens in patients with respiratory allergies: A comparative analysis of allergen-induced skin reactions and their histamine controls |
| title_fullStr |
Immediate skin test reactivity to common aeroallergens in patients with respiratory allergies: A comparative analysis of allergen-induced skin reactions and their histamine controls |
| title_full_unstemmed |
Immediate skin test reactivity to common aeroallergens in patients with respiratory allergies: A comparative analysis of allergen-induced skin reactions and their histamine controls |
| title_sort |
Immediate skin test reactivity to common aeroallergens in patients with respiratory allergies: A comparative analysis of allergen-induced skin reactions and their histamine controls |
| author |
Lopez L.R. |
| author_facet |
Lopez L.R. Noriega Y. Losno R. |
| author_role |
author |
| author2 |
Noriega Y. Losno R. |
| author2_role |
author author |
| dc.contributor.author.fl_str_mv |
Lopez L.R. Noriega Y. Losno R. |
| dc.subject.none.fl_str_mv |
skin test |
| topic |
skin test allergen adolescent adult age aged child controlled study female human major clinical study male priority journal respiratory tract allergy sex difference Adolescent Adult Age Factors Aged Air Pollutants Allergens Child https://purl.org/pe-repo/ocde/ford#1.06.01 |
| dc.subject.es_PE.fl_str_mv |
allergen adolescent adult age aged child controlled study female human major clinical study male priority journal respiratory tract allergy sex difference Adolescent Adult Age Factors Aged Air Pollutants Allergens Child |
| dc.subject.ocde.none.fl_str_mv |
https://purl.org/pe-repo/ocde/ford#1.06.01 |
| description |
From the Department of Microbiology (Immunology Section) Uni-versidad Peruana Cayetano Heredia, Lima, Peru. Supported in part by a grant from Consejo de Ciencia y Tecnologia (CONCYTEC) of Peru. |
| publishDate |
1988 |
| dc.date.accessioned.none.fl_str_mv |
2024-05-30T23:13:38Z |
| dc.date.available.none.fl_str_mv |
2024-05-30T23:13:38Z |
| dc.date.issued.fl_str_mv |
1988 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/20.500.12390/803 |
| dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.1016/0091-6749(88)90882-2 |
| dc.identifier.scopus.none.fl_str_mv |
2-s2.0-0023895334 |
| url |
https://hdl.handle.net/20.500.12390/803 https://doi.org/10.1016/0091-6749(88)90882-2 |
| identifier_str_mv |
2-s2.0-0023895334 |
| dc.language.iso.none.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartof.none.fl_str_mv |
The Journal of Allergy and Clinical Immunology |
| dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Universidad Peruana Cayetano Heredia |
| publisher.none.fl_str_mv |
Universidad Peruana Cayetano Heredia |
| dc.source.none.fl_str_mv |
reponame:CONCYTEC-Institucional instname:Consejo Nacional de Ciencia Tecnología e Innovación instacron:CONCYTEC |
| instname_str |
Consejo Nacional de Ciencia Tecnología e Innovación |
| instacron_str |
CONCYTEC |
| institution |
CONCYTEC |
| reponame_str |
CONCYTEC-Institucional |
| collection |
CONCYTEC-Institucional |
| repository.name.fl_str_mv |
Repositorio Institucional CONCYTEC |
| repository.mail.fl_str_mv |
repositorio@concytec.gob.pe |
| _version_ |
1844883109546295296 |
| spelling |
Publicationrp02062600rp02064600rp02063600Lopez L.R.Noriega Y.Losno R.2024-05-30T23:13:38Z2024-05-30T23:13:38Z1988https://hdl.handle.net/20.500.12390/803https://doi.org/10.1016/0091-6749(88)90882-22-s2.0-0023895334From the Department of Microbiology (Immunology Section) Uni-versidad Peruana Cayetano Heredia, Lima, Peru. Supported in part by a grant from Consejo de Ciencia y Tecnologia (CONCYTEC) of Peru.The results of the immediate skin test response to a panel of 16 common aeroallergens performed in a group of 659 consecutive patients with symptoms suggestive of a respiratory allergy wereanalyzed. A group of 108 healthy individuals served as control subjects. Ninety-four percent of the patients and 87% of the control subjects had at least one allergen-induced reaction (wheal22 by 2 mm). The prevalence of positive skin reactions to each aeroallergen was equally high in both groups. However, if a skin reaction is considered as positive only when anallergen-induced wheal is equal or larger compared to the SO% of the wheal obtained with the histamine control in that individual, 70% of the patients had positive skin reactions and only38% of the control subjects were positive (p < 0.051. Similarly, the prevalence rates to five aeroallergens (pollen, Fusarium, Mucor, Pullularia, and Curvularia) in the patient group were reduced to those levels observed with the control group, suggesting they are clinically less important. The age and not the sex influenced both the prevalence rates (p < 0.001) and the mean size (p < 0.01) of allergen and histamine-induced skin reactions. Lower prevalence rates and mean size values were observed in the youngest group (0 to 9 years). Moreover, thew }was an inverse relationship between lower skin reactivity, with younger subjects in their own patient population. These results indicate that patients and healthy individuals have similar mechanisms for skin reactivity. The size of the allergen-induced wheal reaction compared to the histamine-induced control wheal reaction appears to be an important consideration for the correct clinical interpretation of the results. The observation that there were more younger patients with lower skin reactivity suggests that other mechanisms not detected by skin testing may pie a role in the pathogenesis of respiratory allergies.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - ConcytecengUniversidad Peruana Cayetano HerediaThe Journal of Allergy and Clinical Immunologyinfo:eu-repo/semantics/openAccessskin testallergen-1adolescent-1adult-1age-1aged-1child-1controlled study-1female-1human-1major clinical study-1male-1priority journal-1respiratory tract allergy-1sex difference-1Adolescent-1Adult-1Age Factors-1Aged-1Air Pollutants-1Allergens-1Child-1https://purl.org/pe-repo/ocde/ford#1.06.01-1Immediate skin test reactivity to common aeroallergens in patients with respiratory allergies: A comparative analysis of allergen-induced skin reactions and their histamine controlsinfo:eu-repo/semantics/articlereponame:CONCYTEC-Institucionalinstname:Consejo Nacional de Ciencia Tecnología e Innovacióninstacron:CONCYTEC20.500.12390/803oai:repositorio.concytec.gob.pe:20.500.12390/8032024-05-30 15:59:07.631http://purl.org/coar/access_right/c_14cbinfo:eu-repo/semantics/closedAccessmetadata only accesshttps://repositorio.concytec.gob.peRepositorio Institucional CONCYTECrepositorio@concytec.gob.pe#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="5ddb45f7-8b7d-4cd1-ae4d-7e7322fe8737"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Immediate skin test reactivity to common aeroallergens in patients with respiratory allergies: A comparative analysis of allergen-induced skin reactions and their histamine controls</Title> <PublishedIn> <Publication> <Title>The Journal of Allergy and Clinical Immunology</Title> </Publication> </PublishedIn> <PublicationDate>1988</PublicationDate> <DOI>https://doi.org/10.1016/0091-6749(88)90882-2</DOI> <SCP-Number>2-s2.0-0023895334</SCP-Number> <Authors> <Author> <DisplayName>Lopez L.R.</DisplayName> <Person id="rp02062" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Noriega Y.</DisplayName> <Person id="rp02064" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Losno R.</DisplayName> <Person id="rp02063" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Universidad Peruana Cayetano Heredia</DisplayName> <OrgUnit /> </Publisher> </Publishers> <Keyword>skin test</Keyword> <Keyword>allergen</Keyword> <Keyword>adolescent</Keyword> <Keyword>adult</Keyword> <Keyword>age</Keyword> <Keyword>aged</Keyword> <Keyword>child</Keyword> <Keyword>controlled study</Keyword> <Keyword>female</Keyword> <Keyword>human</Keyword> <Keyword>major clinical study</Keyword> <Keyword>male</Keyword> <Keyword>priority journal</Keyword> <Keyword>respiratory tract allergy</Keyword> <Keyword>sex difference</Keyword> <Keyword>Adolescent</Keyword> <Keyword>Adult</Keyword> <Keyword>Age Factors</Keyword> <Keyword>Aged</Keyword> <Keyword>Air Pollutants</Keyword> <Keyword>Allergens</Keyword> <Keyword>Child</Keyword> <Abstract>The results of the immediate skin test response to a panel of 16 common aeroallergens performed in a group of 659 consecutive patients with symptoms suggestive of a respiratory allergy wereanalyzed. A group of 108 healthy individuals served as control subjects. Ninety-four percent of the patients and 87% of the control subjects had at least one allergen-induced reaction (wheal22 by 2 mm). The prevalence of positive skin reactions to each aeroallergen was equally high in both groups. However, if a skin reaction is considered as positive only when anallergen-induced wheal is equal or larger compared to the SO% of the wheal obtained with the histamine control in that individual, 70% of the patients had positive skin reactions and only38% of the control subjects were positive (p < 0.051. Similarly, the prevalence rates to five aeroallergens (pollen, Fusarium, Mucor, Pullularia, and Curvularia) in the patient group were reduced to those levels observed with the control group, suggesting they are clinically less important. The age and not the sex influenced both the prevalence rates (p < 0.001) and the mean size (p < 0.01) of allergen and histamine-induced skin reactions. Lower prevalence rates and mean size values were observed in the youngest group (0 to 9 years). Moreover, thew }was an inverse relationship between lower skin reactivity, with younger subjects in their own patient population. These results indicate that patients and healthy individuals have similar mechanisms for skin reactivity. The size of the allergen-induced wheal reaction compared to the histamine-induced control wheal reaction appears to be an important consideration for the correct clinical interpretation of the results. The observation that there were more younger patients with lower skin reactivity suggests that other mechanisms not detected by skin testing may pie a role in the pathogenesis of respiratory allergies.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication> -1 |
| score |
13.907986 |
Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
