Association between SLC11A1 polymorphisms and susceptibility to different clinical forms of tuberculosis in the Peruvian population

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This study was supported by Proyecto Vig?´a MINSA/USAID, Lima; Premio Anual de Medicina Francisco Tejada y Sem?´ramis Rea´tegui (Facultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia, UPCH), Lima; Fundacio´n Instituto Hipo´lito Unanue, Lima and Consejo Nacional de Ciencia y Tecn...

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Autores: Taype C.A., Castro J.C., Accinelli R.A., Herrera-Velit P., Shaw M.A., Espinoza J.R.
Formato: artículo
Fecha de Publicación:2006
Institución:Consejo Nacional de Ciencia Tecnología e Innovación
Repositorio:CONCYTEC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorio.concytec.gob.pe:20.500.12390/744
Enlace del recurso:https://hdl.handle.net/20.500.12390/744
https://doi.org/10.1016/j.meegid.2006.01.002
Nivel de acceso:acceso abierto
Materia:unclassified drug
natural resistance associated macrophage protein 1
solute carrier family 11 member A1 protein
3 untranslated region
adult
allele
article
controlled study
extrapulmonary tuberculosis
gene frequency
https://purl.org/pe-repo/ocde/ford#1.06.03
id CONC_bf49d9c630ee6393baf88e37deeb80f2
oai_identifier_str oai:repositorio.concytec.gob.pe:20.500.12390/744
network_acronym_str CONC
network_name_str CONCYTEC-Institucional
repository_id_str 4689
dc.title.none.fl_str_mv Association between SLC11A1 polymorphisms and susceptibility to different clinical forms of tuberculosis in the Peruvian population
title Association between SLC11A1 polymorphisms and susceptibility to different clinical forms of tuberculosis in the Peruvian population
spellingShingle Association between SLC11A1 polymorphisms and susceptibility to different clinical forms of tuberculosis in the Peruvian population
Taype C.A.
unclassified drug
natural resistance associated macrophage protein 1
solute carrier family 11 member A1 protein
3 untranslated region
adult
allele
article
controlled study
extrapulmonary tuberculosis
gene frequency
https://purl.org/pe-repo/ocde/ford#1.06.03
title_short Association between SLC11A1 polymorphisms and susceptibility to different clinical forms of tuberculosis in the Peruvian population
title_full Association between SLC11A1 polymorphisms and susceptibility to different clinical forms of tuberculosis in the Peruvian population
title_fullStr Association between SLC11A1 polymorphisms and susceptibility to different clinical forms of tuberculosis in the Peruvian population
title_full_unstemmed Association between SLC11A1 polymorphisms and susceptibility to different clinical forms of tuberculosis in the Peruvian population
title_sort Association between SLC11A1 polymorphisms and susceptibility to different clinical forms of tuberculosis in the Peruvian population
author Taype C.A.
author_facet Taype C.A.
Castro J.C.
Accinelli R.A.
Herrera-Velit P.
Shaw M.A.
Espinoza J.R.
author_role author
author2 Castro J.C.
Accinelli R.A.
Herrera-Velit P.
Shaw M.A.
Espinoza J.R.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Taype C.A.
Castro J.C.
Accinelli R.A.
Herrera-Velit P.
Shaw M.A.
Espinoza J.R.
dc.subject.none.fl_str_mv unclassified drug
topic unclassified drug
natural resistance associated macrophage protein 1
solute carrier family 11 member A1 protein
3 untranslated region
adult
allele
article
controlled study
extrapulmonary tuberculosis
gene frequency
https://purl.org/pe-repo/ocde/ford#1.06.03
dc.subject.es_PE.fl_str_mv natural resistance associated macrophage protein 1
solute carrier family 11 member A1 protein
3 untranslated region
adult
allele
article
controlled study
extrapulmonary tuberculosis
gene frequency
dc.subject.ocde.none.fl_str_mv https://purl.org/pe-repo/ocde/ford#1.06.03
description This study was supported by Proyecto Vig?´a MINSA/USAID, Lima; Premio Anual de Medicina Francisco Tejada y Sem?´ramis Rea´tegui (Facultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia, UPCH), Lima; Fundacio´n Instituto Hipo´lito Unanue, Lima and Consejo Nacional de Ciencia y Tecnolog?´a (CONCYTEC), Lima-Peru´. CT received support from CONCYETC, the Agreement between Consortium of Francophones Universities of Belgium (CIUF) and UPCH, and the Fundacio´n Cristina e Ismael Cobia´n (Facultad de Ciencias y Filosof?´a Alberto Cazorla Ta´lleri, UPCH). We are very grateful to Dr. Rupert Quinnell for valuable suggestions to this paper.
publishDate 2006
dc.date.accessioned.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.available.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.issued.fl_str_mv 2006
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12390/744
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1016/j.meegid.2006.01.002
dc.identifier.scopus.none.fl_str_mv 2-s2.0-33745374953
url https://hdl.handle.net/20.500.12390/744
https://doi.org/10.1016/j.meegid.2006.01.002
identifier_str_mv 2-s2.0-33745374953
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Infection, Genetics and Evolution
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONCYTEC-Institucional
instname:Consejo Nacional de Ciencia Tecnología e Innovación
instacron:CONCYTEC
instname_str Consejo Nacional de Ciencia Tecnología e Innovación
instacron_str CONCYTEC
institution CONCYTEC
reponame_str CONCYTEC-Institucional
collection CONCYTEC-Institucional
repository.name.fl_str_mv Repositorio Institucional CONCYTEC
repository.mail.fl_str_mv repositorio@concytec.gob.pe
_version_ 1844882996747829248
spelling Publicationrp01899600rp01900600rp01902600rp01897600rp01898600rp01901600Taype C.A.Castro J.C.Accinelli R.A.Herrera-Velit P.Shaw M.A.Espinoza J.R.2024-05-30T23:13:38Z2024-05-30T23:13:38Z2006https://hdl.handle.net/20.500.12390/744https://doi.org/10.1016/j.meegid.2006.01.0022-s2.0-33745374953This study was supported by Proyecto Vig?´a MINSA/USAID, Lima; Premio Anual de Medicina Francisco Tejada y Sem?´ramis Rea´tegui (Facultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia, UPCH), Lima; Fundacio´n Instituto Hipo´lito Unanue, Lima and Consejo Nacional de Ciencia y Tecnolog?´a (CONCYTEC), Lima-Peru´. CT received support from CONCYETC, the Agreement between Consortium of Francophones Universities of Belgium (CIUF) and UPCH, and the Fundacio´n Cristina e Ismael Cobia´n (Facultad de Ciencias y Filosof?´a Alberto Cazorla Ta´lleri, UPCH). We are very grateful to Dr. Rupert Quinnell for valuable suggestions to this paper.Polymorphism in SLC11A1 has been implicated in host susceptibility to tuberculosis. We have studied associations between INT4, D543N, and 3′UTR polymorphisms of SLC11A1 and different clinical forms of TB. Analysis used 507 patients with pulmonary TB, 123 with extra pulmonary TB and 513 controls. INT4 and D543N showed allelic association with pulmonary TB (P = 0.02 and 0.03 respectively). INT4–D543N–3′UTR haplotypes showed an association with pulmonary TB (P = 0.03). No association of SLC11A1 with miliary TB was observed, and a possible association of D543N to the pleural form (P = 0.08) was suggested. These results support association between SLC11A1 and TB, particularly to the common pulmonary form.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - ConcytecengElsevierInfection, Genetics and Evolutioninfo:eu-repo/semantics/openAccessunclassified drugnatural resistance associated macrophage protein 1-1solute carrier family 11 member A1 protein-13 untranslated region-1adult-1allele-1article-1controlled study-1extrapulmonary tuberculosis-1gene frequency-1https://purl.org/pe-repo/ocde/ford#1.06.03-1Association between SLC11A1 polymorphisms and susceptibility to different clinical forms of tuberculosis in the Peruvian populationinfo:eu-repo/semantics/articlereponame:CONCYTEC-Institucionalinstname:Consejo Nacional de Ciencia Tecnología e Innovacióninstacron:CONCYTEC20.500.12390/744oai:repositorio.concytec.gob.pe:20.500.12390/7442024-05-30 15:58:52.74http://purl.org/coar/access_right/c_14cbinfo:eu-repo/semantics/closedAccessmetadata only accesshttps://repositorio.concytec.gob.peRepositorio Institucional CONCYTECrepositorio@concytec.gob.pe#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="8b227c39-50d5-45e4-abe0-82fe13ce3fc0"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Association between SLC11A1 polymorphisms and susceptibility to different clinical forms of tuberculosis in the Peruvian population</Title> <PublishedIn> <Publication> <Title>Infection, Genetics and Evolution</Title> </Publication> </PublishedIn> <PublicationDate>2006</PublicationDate> <DOI>https://doi.org/10.1016/j.meegid.2006.01.002</DOI> <SCP-Number>2-s2.0-33745374953</SCP-Number> <Authors> <Author> <DisplayName>Taype C.A.</DisplayName> <Person id="rp01899" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Castro J.C.</DisplayName> <Person id="rp01900" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Accinelli R.A.</DisplayName> <Person id="rp01902" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Herrera-Velit P.</DisplayName> <Person id="rp01897" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Shaw M.A.</DisplayName> <Person id="rp01898" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Espinoza J.R.</DisplayName> <Person id="rp01901" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Elsevier</DisplayName> <OrgUnit /> </Publisher> </Publishers> <Keyword>unclassified drug</Keyword> <Keyword>natural resistance associated macrophage protein 1</Keyword> <Keyword>solute carrier family 11 member A1 protein</Keyword> <Keyword>3 untranslated region</Keyword> <Keyword>adult</Keyword> <Keyword>allele</Keyword> <Keyword>article</Keyword> <Keyword>controlled study</Keyword> <Keyword>extrapulmonary tuberculosis</Keyword> <Keyword>gene frequency</Keyword> <Abstract>Polymorphism in SLC11A1 has been implicated in host susceptibility to tuberculosis. We have studied associations between INT4, D543N, and 3′UTR polymorphisms of SLC11A1 and different clinical forms of TB. Analysis used 507 patients with pulmonary TB, 123 with extra pulmonary TB and 513 controls. INT4 and D543N showed allelic association with pulmonary TB (P = 0.02 and 0.03 respectively). INT4–D543N–3′UTR haplotypes showed an association with pulmonary TB (P = 0.03). No association of SLC11A1 with miliary TB was observed, and a possible association of D543N to the pleural form (P = 0.08) was suggested. These results support association between SLC11A1 and TB, particularly to the common pulmonary form.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication> -1
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