Human monocyte response to Andean-native starch nanoparticles

Descripción del Articulo

We used starches from two different Andean-native tubers to prepare nano-sized particles, and tested their ability to stimulate inflammatory reactions in human monocytes. Our data show that the release of inflammatory cytokines by monocytes can be differentially modulated by the administration of no...

Descripción completa

Detalles Bibliográficos
Autores: Gatto, Francesca, Troncoso, Omar P, Brunetti, Virgilio, Malvindi, Maria Ada, Pompa, Pier Paolo, Torres, Fernando G, Bardi, Giuseppe
Formato: artículo
Fecha de Publicación:2016
Institución:Consejo Nacional de Ciencia Tecnología e Innovación
Repositorio:CONCYTEC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorio.concytec.gob.pe:20.500.12390/1292
Enlace del recurso:https://hdl.handle.net/20.500.12390/1292
https://doi.org/10.1002/star.201600105
Nivel de acceso:acceso abierto
Materia:Nanopartículas
Inflamación
Monocitos
Estado
https://purl.org/pe-repo/ocde/ford#1.06.16
id CONC_a8477fb63290b6615777a09127b0ca07
oai_identifier_str oai:repositorio.concytec.gob.pe:20.500.12390/1292
network_acronym_str CONC
network_name_str CONCYTEC-Institucional
repository_id_str 4689
dc.title.none.fl_str_mv Human monocyte response to Andean-native starch nanoparticles
title Human monocyte response to Andean-native starch nanoparticles
spellingShingle Human monocyte response to Andean-native starch nanoparticles
Gatto, Francesca
Nanopartículas
Inflamación
Inflamación
Monocitos
Estado
https://purl.org/pe-repo/ocde/ford#1.06.16
title_short Human monocyte response to Andean-native starch nanoparticles
title_full Human monocyte response to Andean-native starch nanoparticles
title_fullStr Human monocyte response to Andean-native starch nanoparticles
title_full_unstemmed Human monocyte response to Andean-native starch nanoparticles
title_sort Human monocyte response to Andean-native starch nanoparticles
author Gatto, Francesca
author_facet Gatto, Francesca
Troncoso, Omar P
Brunetti, Virgilio
Malvindi, Maria Ada
Pompa, Pier Paolo
Torres, Fernando G
Bardi, Giuseppe
author_role author
author2 Troncoso, Omar P
Brunetti, Virgilio
Malvindi, Maria Ada
Pompa, Pier Paolo
Torres, Fernando G
Bardi, Giuseppe
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gatto, Francesca
Troncoso, Omar P
Brunetti, Virgilio
Malvindi, Maria Ada
Pompa, Pier Paolo
Torres, Fernando G
Bardi, Giuseppe
dc.subject.none.fl_str_mv Nanopartículas
topic Nanopartículas
Inflamación
Inflamación
Monocitos
Estado
https://purl.org/pe-repo/ocde/ford#1.06.16
dc.subject.es_PE.fl_str_mv Inflamación
Inflamación
Monocitos
Estado
dc.subject.ocde.none.fl_str_mv https://purl.org/pe-repo/ocde/ford#1.06.16
description We used starches from two different Andean-native tubers to prepare nano-sized particles, and tested their ability to stimulate inflammatory reactions in human monocytes. Our data show that the release of inflammatory cytokines by monocytes can be differentially modulated by the administration of non-toxic doses of nanoparticles synthesized from the starch of the Andean sub-species Solanum tuberosum and Solanum goniocalyx. Furthermore, we observed a starch-nanoparticle-specific increase in inflammatory chemokine-dependent migration, and an up-regulation of immunoglobulin receptor CD16. Based on this preliminary study, we conclude that different potato starch nanoparticles possess specific properties that can induce immune responses and may be employed as immune modulators in the future.
publishDate 2016
dc.date.accessioned.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.available.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.issued.fl_str_mv 2016-06-20
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12390/1292
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1002/star.201600105
url https://hdl.handle.net/20.500.12390/1292
https://doi.org/10.1002/star.201600105
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Starch - Stärke
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:CONCYTEC-Institucional
instname:Consejo Nacional de Ciencia Tecnología e Innovación
instacron:CONCYTEC
instname_str Consejo Nacional de Ciencia Tecnología e Innovación
instacron_str CONCYTEC
institution CONCYTEC
reponame_str CONCYTEC-Institucional
collection CONCYTEC-Institucional
repository.name.fl_str_mv Repositorio Institucional CONCYTEC
repository.mail.fl_str_mv repositorio@concytec.gob.pe
_version_ 1844883054248591360
spelling Publicationrp03754600rp03752600rp03756600rp03753600rp03755600rp03703500rp03705500Gatto, FrancescaTroncoso, Omar PBrunetti, VirgilioMalvindi, Maria AdaPompa, Pier PaoloTorres, Fernando GBardi, Giuseppe2024-05-30T23:13:38Z2024-05-30T23:13:38Z2016-06-20https://hdl.handle.net/20.500.12390/1292https://doi.org/10.1002/star.201600105We used starches from two different Andean-native tubers to prepare nano-sized particles, and tested their ability to stimulate inflammatory reactions in human monocytes. Our data show that the release of inflammatory cytokines by monocytes can be differentially modulated by the administration of non-toxic doses of nanoparticles synthesized from the starch of the Andean sub-species Solanum tuberosum and Solanum goniocalyx. Furthermore, we observed a starch-nanoparticle-specific increase in inflammatory chemokine-dependent migration, and an up-regulation of immunoglobulin receptor CD16. Based on this preliminary study, we conclude that different potato starch nanoparticles possess specific properties that can induce immune responses and may be employed as immune modulators in the future.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - ConcytecengWileyStarch - Stärkeinfo:eu-repo/semantics/openAccessNanopartículasInflamación-1Inflamación-1Monocitos-1Estado-1https://purl.org/pe-repo/ocde/ford#1.06.16-1Human monocyte response to Andean-native starch nanoparticlesinfo:eu-repo/semantics/articlereponame:CONCYTEC-Institucionalinstname:Consejo Nacional de Ciencia Tecnología e Innovacióninstacron:CONCYTEC20.500.12390/1292oai:repositorio.concytec.gob.pe:20.500.12390/12922024-05-30 16:02:24.62http://purl.org/coar/access_right/c_14cbinfo:eu-repo/semantics/closedAccessmetadata only accesshttps://repositorio.concytec.gob.peRepositorio Institucional CONCYTECrepositorio@concytec.gob.pe#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="0d4c690f-7b96-41ba-bf85-83ac05eead13"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Human monocyte response to Andean-native starch nanoparticles</Title> <PublishedIn> <Publication> <Title>Starch - Stärke</Title> </Publication> </PublishedIn> <PublicationDate>2016-06-20</PublicationDate> <DOI>https://doi.org/10.1002/star.201600105</DOI> <Authors> <Author> <DisplayName>Gatto, Francesca</DisplayName> <Person id="rp03754" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Troncoso, Omar P</DisplayName> <Person id="rp03752" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Brunetti, Virgilio</DisplayName> <Person id="rp03756" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Malvindi, Maria Ada</DisplayName> <Person id="rp03753" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Pompa, Pier Paolo</DisplayName> <Person id="rp03755" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Torres, Fernando G</DisplayName> <Person id="rp03703" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Bardi, Giuseppe</DisplayName> <Person id="rp03705" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Wiley</DisplayName> <OrgUnit /> </Publisher> </Publishers> <Keyword>Nanopartículas</Keyword> <Keyword>Inflamación</Keyword> <Keyword>Inflamación</Keyword> <Keyword>Monocitos</Keyword> <Keyword>Estado</Keyword> <Abstract>We used starches from two different Andean-native tubers to prepare nano-sized particles, and tested their ability to stimulate inflammatory reactions in human monocytes. Our data show that the release of inflammatory cytokines by monocytes can be differentially modulated by the administration of non-toxic doses of nanoparticles synthesized from the starch of the Andean sub-species Solanum tuberosum and Solanum goniocalyx. Furthermore, we observed a starch-nanoparticle-specific increase in inflammatory chemokine-dependent migration, and an up-regulation of immunoglobulin receptor CD16. Based on this preliminary study, we conclude that different potato starch nanoparticles possess specific properties that can induce immune responses and may be employed as immune modulators in the future.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication> -1
score 13.413352
Human monocyte response to Andean-native starch nanoparticles
Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).

Ejemplares Similares