Neutralization of toxicological activities of medically-relevant Bothrops snake venoms and relevant toxins by two polyvalent bothropic antivenoms produced in Peru and Brazil
Descripción del Articulo
Snakebite envenoming is a neglected public pathology, affecting especially rural communities or isolated areas of tropical and subtropical Latin American countries. The parenteral administration of antivenom is the mainstay and the only validated treatment of snake bite envenoming. Here, we assess t...
| Autores: | , , , , , , , , |
|---|---|
| Formato: | artículo |
| Fecha de Publicación: | 2016 |
| Institución: | Consejo Nacional de Ciencia Tecnología e Innovación |
| Repositorio: | CONCYTEC-Institucional |
| Lenguaje: | inglés |
| OAI Identifier: | oai:repositorio.concytec.gob.pe:20.500.12390/711 |
| Enlace del recurso: | https://hdl.handle.net/20.500.12390/711 https://doi.org/10.1016/j.toxicon.2016.09.010 |
| Nivel de acceso: | acceso abierto |
| Materia: | venom antiserum snake venom snake venom antiserum https://purl.org/pe-repo/ocde/ford#4.03.00 |
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4689 |
| dc.title.none.fl_str_mv |
Neutralization of toxicological activities of medically-relevant Bothrops snake venoms and relevant toxins by two polyvalent bothropic antivenoms produced in Peru and Brazil |
| title |
Neutralization of toxicological activities of medically-relevant Bothrops snake venoms and relevant toxins by two polyvalent bothropic antivenoms produced in Peru and Brazil |
| spellingShingle |
Neutralization of toxicological activities of medically-relevant Bothrops snake venoms and relevant toxins by two polyvalent bothropic antivenoms produced in Peru and Brazil Estevao-Costa M.I. venom antiserum snake venom snake venom antiserum snake venom https://purl.org/pe-repo/ocde/ford#4.03.00 |
| title_short |
Neutralization of toxicological activities of medically-relevant Bothrops snake venoms and relevant toxins by two polyvalent bothropic antivenoms produced in Peru and Brazil |
| title_full |
Neutralization of toxicological activities of medically-relevant Bothrops snake venoms and relevant toxins by two polyvalent bothropic antivenoms produced in Peru and Brazil |
| title_fullStr |
Neutralization of toxicological activities of medically-relevant Bothrops snake venoms and relevant toxins by two polyvalent bothropic antivenoms produced in Peru and Brazil |
| title_full_unstemmed |
Neutralization of toxicological activities of medically-relevant Bothrops snake venoms and relevant toxins by two polyvalent bothropic antivenoms produced in Peru and Brazil |
| title_sort |
Neutralization of toxicological activities of medically-relevant Bothrops snake venoms and relevant toxins by two polyvalent bothropic antivenoms produced in Peru and Brazil |
| author |
Estevao-Costa M.I. |
| author_facet |
Estevao-Costa M.I. Gontijo S.S. Correia B.L. Yarleque A. Vivas-Ruiz D. Rodrigues E. Chávez-Olortegui C. Oliveira L.S. Sanchez E.F. |
| author_role |
author |
| author2 |
Gontijo S.S. Correia B.L. Yarleque A. Vivas-Ruiz D. Rodrigues E. Chávez-Olortegui C. Oliveira L.S. Sanchez E.F. |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Estevao-Costa M.I. Gontijo S.S. Correia B.L. Yarleque A. Vivas-Ruiz D. Rodrigues E. Chávez-Olortegui C. Oliveira L.S. Sanchez E.F. |
| dc.subject.none.fl_str_mv |
venom antiserum |
| topic |
venom antiserum snake venom snake venom antiserum snake venom https://purl.org/pe-repo/ocde/ford#4.03.00 |
| dc.subject.es_PE.fl_str_mv |
snake venom snake venom antiserum snake venom |
| dc.subject.ocde.none.fl_str_mv |
https://purl.org/pe-repo/ocde/ford#4.03.00 |
| description |
Snakebite envenoming is a neglected public pathology, affecting especially rural communities or isolated areas of tropical and subtropical Latin American countries. The parenteral administration of antivenom is the mainstay and the only validated treatment of snake bite envenoming. Here, we assess the efficacy of polyspecific anti-Bothrops serum (α-BS) produced in the Instituto Nacional de Salud (INS, Peru) and at the Fundação Ezequiel Dias (FUNED, Brazil), to neutralize the main toxic activities induced by five medically-relevant venoms of: Bothrops atrox, B. barnetti, and B. pictus from Peru, and the Brazilian B. jararaca and B. leucurus, all of them inhabiting different geographical locations. |
| publishDate |
2016 |
| dc.date.accessioned.none.fl_str_mv |
2024-05-30T23:13:38Z |
| dc.date.available.none.fl_str_mv |
2024-05-30T23:13:38Z |
| dc.date.issued.fl_str_mv |
2016 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/20.500.12390/711 |
| dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.1016/j.toxicon.2016.09.010 |
| dc.identifier.scopus.none.fl_str_mv |
2-s2.0-84988807934 |
| url |
https://hdl.handle.net/20.500.12390/711 https://doi.org/10.1016/j.toxicon.2016.09.010 |
| identifier_str_mv |
2-s2.0-84988807934 |
| dc.language.iso.none.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartof.none.fl_str_mv |
Toxicon |
| dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Elsevier |
| publisher.none.fl_str_mv |
Elsevier |
| dc.source.none.fl_str_mv |
reponame:CONCYTEC-Institucional instname:Consejo Nacional de Ciencia Tecnología e Innovación instacron:CONCYTEC |
| instname_str |
Consejo Nacional de Ciencia Tecnología e Innovación |
| instacron_str |
CONCYTEC |
| institution |
CONCYTEC |
| reponame_str |
CONCYTEC-Institucional |
| collection |
CONCYTEC-Institucional |
| repository.name.fl_str_mv |
Repositorio Institucional CONCYTEC |
| repository.mail.fl_str_mv |
repositorio@concytec.gob.pe |
| _version_ |
1844883017470836736 |
| spelling |
Publicationrp01731600rp01732600rp01734600rp01733600rp01737600rp01735600rp01736600rp01730600rp01738600Estevao-Costa M.I.Gontijo S.S.Correia B.L.Yarleque A.Vivas-Ruiz D.Rodrigues E.Chávez-Olortegui C.Oliveira L.S.Sanchez E.F.2024-05-30T23:13:38Z2024-05-30T23:13:38Z2016https://hdl.handle.net/20.500.12390/711https://doi.org/10.1016/j.toxicon.2016.09.0102-s2.0-84988807934Snakebite envenoming is a neglected public pathology, affecting especially rural communities or isolated areas of tropical and subtropical Latin American countries. The parenteral administration of antivenom is the mainstay and the only validated treatment of snake bite envenoming. Here, we assess the efficacy of polyspecific anti-Bothrops serum (α-BS) produced in the Instituto Nacional de Salud (INS, Peru) and at the Fundação Ezequiel Dias (FUNED, Brazil), to neutralize the main toxic activities induced by five medically-relevant venoms of: Bothrops atrox, B. barnetti, and B. pictus from Peru, and the Brazilian B. jararaca and B. leucurus, all of them inhabiting different geographical locations.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - ConcytecengElsevierToxiconinfo:eu-repo/semantics/openAccessvenom antiserumsnake venom-1snake venom antiserum-1snake venom-1https://purl.org/pe-repo/ocde/ford#4.03.00-1Neutralization of toxicological activities of medically-relevant Bothrops snake venoms and relevant toxins by two polyvalent bothropic antivenoms produced in Peru and Brazilinfo:eu-repo/semantics/articlereponame:CONCYTEC-Institucionalinstname:Consejo Nacional de Ciencia Tecnología e Innovacióninstacron:CONCYTEC20.500.12390/711oai:repositorio.concytec.gob.pe:20.500.12390/7112024-05-30 15:49:38.465http://purl.org/coar/access_right/c_14cbinfo:eu-repo/semantics/closedAccessmetadata only accesshttps://repositorio.concytec.gob.peRepositorio Institucional CONCYTECrepositorio@concytec.gob.pe#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="b25adf91-695a-475f-8122-bf4c2534063d"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Neutralization of toxicological activities of medically-relevant Bothrops snake venoms and relevant toxins by two polyvalent bothropic antivenoms produced in Peru and Brazil</Title> <PublishedIn> <Publication> <Title>Toxicon</Title> </Publication> </PublishedIn> <PublicationDate>2016</PublicationDate> <DOI>https://doi.org/10.1016/j.toxicon.2016.09.010</DOI> <SCP-Number>2-s2.0-84988807934</SCP-Number> <Authors> <Author> <DisplayName>Estevao-Costa M.I.</DisplayName> <Person id="rp01731" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Gontijo S.S.</DisplayName> <Person id="rp01732" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Correia B.L.</DisplayName> <Person id="rp01734" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Yarleque A.</DisplayName> <Person id="rp01733" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Vivas-Ruiz D.</DisplayName> <Person id="rp01737" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Rodrigues E.</DisplayName> <Person id="rp01735" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Chávez-Olortegui C.</DisplayName> <Person id="rp01736" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Oliveira L.S.</DisplayName> <Person id="rp01730" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Sanchez E.F.</DisplayName> <Person id="rp01738" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Elsevier</DisplayName> <OrgUnit /> </Publisher> </Publishers> <Keyword>venom antiserum</Keyword> <Keyword>snake venom</Keyword> <Keyword>snake venom antiserum</Keyword> <Keyword>snake venom</Keyword> <Abstract>Snakebite envenoming is a neglected public pathology, affecting especially rural communities or isolated areas of tropical and subtropical Latin American countries. The parenteral administration of antivenom is the mainstay and the only validated treatment of snake bite envenoming. Here, we assess the efficacy of polyspecific anti-Bothrops serum (α-BS) produced in the Instituto Nacional de Salud (INS, Peru) and at the Fundação Ezequiel Dias (FUNED, Brazil), to neutralize the main toxic activities induced by five medically-relevant venoms of: Bothrops atrox, B. barnetti, and B. pictus from Peru, and the Brazilian B. jararaca and B. leucurus, all of them inhabiting different geographical locations.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication> -1 |
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13.413352 |
Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
