Computational and experimental analysis of a Glaucoma flat drainage device

Descripción del Articulo

The authors would like to thank to FONDECYT-UK J008-2016 for the financial support during the course of this work.
Detalles Bibliográficos
Autores: Panduro, R. M. R., Monterrey, Christian, Mantari, J. L., Canahuire, Ruth, Alvarez, Helard, Miranda, Mario, Elsheikh, Ahmed
Formato: artículo
Fecha de Publicación:2021
Institución:Consejo Nacional de Ciencia Tecnología e Innovación
Repositorio:CONCYTEC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorio.concytec.gob.pe:20.500.12390/2925
Enlace del recurso:https://hdl.handle.net/20.500.12390/2925
https://doi.org/10.1016/j.jbiomech.2021.110234
Nivel de acceso:acceso abierto
Materia:Thin-film fluid
Glaucoma
Fluid-structure interaction
Glaucoma drainage device (GDD)
Finite element method
https://purl.org/pe-repo/ocde/ford#2.02.04
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network_acronym_str CONC
network_name_str CONCYTEC-Institucional
repository_id_str 4689
dc.title.none.fl_str_mv Computational and experimental analysis of a Glaucoma flat drainage device
title Computational and experimental analysis of a Glaucoma flat drainage device
spellingShingle Computational and experimental analysis of a Glaucoma flat drainage device
Panduro, R. M. R.
Thin-film fluid
Glaucoma
Fluid-structure interaction
Fluid-structure interaction
Glaucoma drainage device (GDD)
Finite element method
https://purl.org/pe-repo/ocde/ford#2.02.04
title_short Computational and experimental analysis of a Glaucoma flat drainage device
title_full Computational and experimental analysis of a Glaucoma flat drainage device
title_fullStr Computational and experimental analysis of a Glaucoma flat drainage device
title_full_unstemmed Computational and experimental analysis of a Glaucoma flat drainage device
title_sort Computational and experimental analysis of a Glaucoma flat drainage device
author Panduro, R. M. R.
author_facet Panduro, R. M. R.
Monterrey, Christian
Mantari, J. L.
Canahuire, Ruth
Alvarez, Helard
Miranda, Mario
Elsheikh, Ahmed
author_role author
author2 Monterrey, Christian
Mantari, J. L.
Canahuire, Ruth
Alvarez, Helard
Miranda, Mario
Elsheikh, Ahmed
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Panduro, R. M. R.
Monterrey, Christian
Mantari, J. L.
Canahuire, Ruth
Alvarez, Helard
Miranda, Mario
Elsheikh, Ahmed
dc.subject.none.fl_str_mv Thin-film fluid
topic Thin-film fluid
Glaucoma
Fluid-structure interaction
Fluid-structure interaction
Glaucoma drainage device (GDD)
Finite element method
https://purl.org/pe-repo/ocde/ford#2.02.04
dc.subject.es_PE.fl_str_mv Glaucoma
Fluid-structure interaction
Fluid-structure interaction
Glaucoma drainage device (GDD)
Finite element method
dc.subject.ocde.none.fl_str_mv https://purl.org/pe-repo/ocde/ford#2.02.04
description The authors would like to thank to FONDECYT-UK J008-2016 for the financial support during the course of this work.
publishDate 2021
dc.date.accessioned.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.available.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.issued.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12390/2925
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1016/j.jbiomech.2021.110234
url https://hdl.handle.net/20.500.12390/2925
https://doi.org/10.1016/j.jbiomech.2021.110234
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv JOURNAL OF BIOMECHANICS
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier Ltd
publisher.none.fl_str_mv Elsevier Ltd
dc.source.none.fl_str_mv reponame:CONCYTEC-Institucional
instname:Consejo Nacional de Ciencia Tecnología e Innovación
instacron:CONCYTEC
instname_str Consejo Nacional de Ciencia Tecnología e Innovación
instacron_str CONCYTEC
institution CONCYTEC
reponame_str CONCYTEC-Institucional
collection CONCYTEC-Institucional
repository.name.fl_str_mv Repositorio Institucional CONCYTEC
repository.mail.fl_str_mv repositorio@concytec.gob.pe
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spelling Publicationrp08164600rp08160600rp08159600rp08161600rp08162600rp08165600rp08163600Panduro, R. M. R.Monterrey, ChristianMantari, J. L.Canahuire, RuthAlvarez, HelardMiranda, MarioElsheikh, Ahmed2024-05-30T23:13:38Z2024-05-30T23:13:38Z2021https://hdl.handle.net/20.500.12390/2925https://doi.org/10.1016/j.jbiomech.2021.110234The authors would like to thank to FONDECYT-UK J008-2016 for the financial support during the course of this work.This paper presents a computational and experimental analysis of a glaucoma flat drainage device (FDD). The FDD consists of a metallic microplate placed into the eye sclerocorneal limbus, which creates a virtual path between the anterior chamber and its exterior, allowing the intraocular pressure (LOP) to be kept in a normal range. It also uses the surrounding tissue as a flow regulator in order to provide close values of LOP for a wide range of aqueous humor (AH) flow rates. The Neo Hookean hyperelastic model is used for the solid part, while the Reynolds thin film fluid model is used for the fluid part. On the other hand, a gravitational-driven flow test is implemented in order to validate the simulation process. An in vitro experiment evaluated the flow characteristics of the device implanted in fourteen extirpated pig eyes, giving as a result the best-fit for the Young modulus of the tissue surrounding the device. Finally, according to the resulting computational model, for a range of 1.4-3.1 mu L/min, the device presents a pressure variation range of 6-7.5 mmHg. (C) 2021 Published by Elsevier Ltd.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - ConcytecengElsevier LtdJOURNAL OF BIOMECHANICSinfo:eu-repo/semantics/openAccessThin-film fluidGlaucoma-1Fluid-structure interaction-1Fluid-structure interaction-1Glaucoma drainage device (GDD)-1Finite element method-1https://purl.org/pe-repo/ocde/ford#2.02.04-1Computational and experimental analysis of a Glaucoma flat drainage deviceinfo:eu-repo/semantics/articlereponame:CONCYTEC-Institucionalinstname:Consejo Nacional de Ciencia Tecnología e Innovacióninstacron:CONCYTEC20.500.12390/2925oai:repositorio.concytec.gob.pe:20.500.12390/29252024-05-30 16:12:12.136http://purl.org/coar/access_right/c_14cbinfo:eu-repo/semantics/closedAccessmetadata only accesshttps://repositorio.concytec.gob.peRepositorio Institucional CONCYTECrepositorio@concytec.gob.pe#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="ff9d62c0-c0bf-4b31-9511-03f7483f21e9"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Computational and experimental analysis of a Glaucoma flat drainage device</Title> <PublishedIn> <Publication> <Title>JOURNAL OF BIOMECHANICS</Title> </Publication> </PublishedIn> <PublicationDate>2021</PublicationDate> <DOI>https://doi.org/10.1016/j.jbiomech.2021.110234</DOI> <Authors> <Author> <DisplayName>Panduro, R. M. R.</DisplayName> <Person id="rp08164" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Monterrey, Christian</DisplayName> <Person id="rp08160" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Mantari, J. L.</DisplayName> <Person id="rp08159" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Canahuire, Ruth</DisplayName> <Person id="rp08161" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Alvarez, Helard</DisplayName> <Person id="rp08162" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Miranda, Mario</DisplayName> <Person id="rp08165" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Elsheikh, Ahmed</DisplayName> <Person id="rp08163" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Elsevier Ltd</DisplayName> <OrgUnit /> </Publisher> </Publishers> <Keyword>Thin-film fluid</Keyword> <Keyword>Glaucoma</Keyword> <Keyword>Fluid-structure interaction</Keyword> <Keyword>Fluid-structure interaction</Keyword> <Keyword>Glaucoma drainage device (GDD)</Keyword> <Keyword>Finite element method</Keyword> <Abstract>This paper presents a computational and experimental analysis of a glaucoma flat drainage device (FDD). The FDD consists of a metallic microplate placed into the eye sclerocorneal limbus, which creates a virtual path between the anterior chamber and its exterior, allowing the intraocular pressure (LOP) to be kept in a normal range. It also uses the surrounding tissue as a flow regulator in order to provide close values of LOP for a wide range of aqueous humor (AH) flow rates. The Neo Hookean hyperelastic model is used for the solid part, while the Reynolds thin film fluid model is used for the fluid part. On the other hand, a gravitational-driven flow test is implemented in order to validate the simulation process. An in vitro experiment evaluated the flow characteristics of the device implanted in fourteen extirpated pig eyes, giving as a result the best-fit for the Young modulus of the tissue surrounding the device. Finally, according to the resulting computational model, for a range of 1.4-3.1 mu L/min, the device presents a pressure variation range of 6-7.5 mmHg. (C) 2021 Published by Elsevier Ltd.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication> -1
score 13.461011
Computational and experimental analysis of a Glaucoma flat drainage device
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