Characterization of DNA ADP-ribosyltransferase activities of PARP2 and PARP3: New insights into DNA ADP-ribosylation

• Autores: Zarkovic G., Belousova E.A., Talhaoui I., Saint-Pierre C., Kutuzov M.M., Matkarimov B.T., Biard D., Gasparutto D., Lavrik O.I., Ishchenko A.A.
• Formato: artículo
• Fecha de Publicación: 2018
• Institución: Consejo Nacional de Ciencia Tecnología e Innovación
• Repositorio: CONCYTEC-Institucional
• Lenguaje: inglés
• OAI Identifier: oai:repositorio.concytec.gob.pe:20.500.12390/549
• Enlace del recurso: https://hdl.handle.net/20.500.12390/549; https://doi.org/10.1093/nar/gkx1318
• Nivel de acceso: acceso abierto
• Materia: unclassified drug; bleomycin; DNA; genomic DNA; glycosidase; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase 2; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase 3; poly(adenosine diphosphate ribose); Article; cell free system; controlled study; DNA damage; DNA modification; DNA replication; double stranded DNA break; enzyme active site; enzyme activity; enzyme mechanism; enzyme specificity; HeLa cell line; human; human cell; molecular weight; mono adenosine diphosphate ribosylation; priority journal; single stranded DNA break; https://purl.org/pe-repo/ocde/ford#3.01.02

Fondation ARC (http://www.arc-cancer.net) [PJA20151203415 to A.A.I.]; ERA.Net RUS Plus (www.eranet-rus.eu) [DNA PARYLATION #306 to A.A.I., RFBR-16–54-76010 to O.I.L.]; Ministry of Education and Science of the Republic of Kazakhstan [programs 0115RK02473 and 0115RK03029 to B.T.M.]; NU ORAU (http://www.nu.edu.kz) (to B.T.M.); RSF Grant [14–24-00038 to O.I.L.]; French National Research Agency ‘Labex program’ [ARCANE project ANR-11-LABX-0003–01 to C.S.-P., D.G.]; Fondation ARC Postdoctoral Fellowship (http://www.arc-cancer.net) [PDF20110603195 to I.T.]; CIENCIACTIVA/CONCYTEC Doctoral Fellowship (www.cienciactiva.gob.pe) (to G.Z.). Funding for open access charge: National Laboratory Astana, Nazarbayev University, Astana, Republic of Kazakhstan.