Current practices in missing data handling for interrupted time series studies performed on individual-level data: A scoping review in health research

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This study was funded by the National Institute for Health Research (NIHR) School for Primary Care Research, project number 444. JCB was sponsored by FONDECYT- CONCYTEC (grant contract number 231-2015- FONDECYT). TPM, TMP and JRC were supported by the Medical Research Council (grant numbers MC_UU_12...

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Detalles Bibliográficos
Autores: Bazo-Alvarez J.C., Morris T.P., Carpenter J.R., Petersen I.
Formato: revisión
Fecha de Publicación:2021
Institución:Consejo Nacional de Ciencia Tecnología e Innovación
Repositorio:CONCYTEC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorio.concytec.gob.pe:20.500.12390/2988
Enlace del recurso:https://hdl.handle.net/20.500.12390/2988
https://doi.org/10.2147/CLEP.S314020
Nivel de acceso:acceso abierto
Materia:Segmented regression
Interrupted time series analysis
Missing data
Multiple imputation
Scoping review
https://purl.org/pe-repo/ocde/ford#2.02.04
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network_acronym_str CONC
network_name_str CONCYTEC-Institucional
repository_id_str 4689
dc.title.none.fl_str_mv Current practices in missing data handling for interrupted time series studies performed on individual-level data: A scoping review in health research
title Current practices in missing data handling for interrupted time series studies performed on individual-level data: A scoping review in health research
spellingShingle Current practices in missing data handling for interrupted time series studies performed on individual-level data: A scoping review in health research
Bazo-Alvarez J.C.
Segmented regression
Interrupted time series analysis
Missing data
Multiple imputation
Scoping review
https://purl.org/pe-repo/ocde/ford#2.02.04
title_short Current practices in missing data handling for interrupted time series studies performed on individual-level data: A scoping review in health research
title_full Current practices in missing data handling for interrupted time series studies performed on individual-level data: A scoping review in health research
title_fullStr Current practices in missing data handling for interrupted time series studies performed on individual-level data: A scoping review in health research
title_full_unstemmed Current practices in missing data handling for interrupted time series studies performed on individual-level data: A scoping review in health research
title_sort Current practices in missing data handling for interrupted time series studies performed on individual-level data: A scoping review in health research
author Bazo-Alvarez J.C.
author_facet Bazo-Alvarez J.C.
Morris T.P.
Carpenter J.R.
Petersen I.
author_role author
author2 Morris T.P.
Carpenter J.R.
Petersen I.
author2_role author
author
author
dc.contributor.author.fl_str_mv Bazo-Alvarez J.C.
Morris T.P.
Carpenter J.R.
Petersen I.
dc.subject.none.fl_str_mv Segmented regression
topic Segmented regression
Interrupted time series analysis
Missing data
Multiple imputation
Scoping review
https://purl.org/pe-repo/ocde/ford#2.02.04
dc.subject.es_PE.fl_str_mv Interrupted time series analysis
Missing data
Multiple imputation
Scoping review
dc.subject.ocde.none.fl_str_mv https://purl.org/pe-repo/ocde/ford#2.02.04
description This study was funded by the National Institute for Health Research (NIHR) School for Primary Care Research, project number 444. JCB was sponsored by FONDECYT- CONCYTEC (grant contract number 231-2015- FONDECYT). TPM, TMP and JRC were supported by the Medical Research Council (grant numbers MC_UU_12023/ 21 and MC_UU_12023/29). The study sponsors only had a funding role in this research. Thus, the researchers worked with total independence from their sponsors.
publishDate 2021
dc.date.accessioned.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.available.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.issued.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/review
format review
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12390/2988
dc.identifier.doi.none.fl_str_mv https://doi.org/10.2147/CLEP.S314020
dc.identifier.scopus.none.fl_str_mv 2-s2.0-85111702945
url https://hdl.handle.net/20.500.12390/2988
https://doi.org/10.2147/CLEP.S314020
identifier_str_mv 2-s2.0-85111702945
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Clinical Epidemiology
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.uri.none.fl_str_mv https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0/
dc.publisher.none.fl_str_mv Dove Medical Press Ltd
publisher.none.fl_str_mv Dove Medical Press Ltd
dc.source.none.fl_str_mv reponame:CONCYTEC-Institucional
instname:Consejo Nacional de Ciencia Tecnología e Innovación
instacron:CONCYTEC
instname_str Consejo Nacional de Ciencia Tecnología e Innovación
instacron_str CONCYTEC
institution CONCYTEC
reponame_str CONCYTEC-Institucional
collection CONCYTEC-Institucional
repository.name.fl_str_mv Repositorio Institucional CONCYTEC
repository.mail.fl_str_mv repositorio@concytec.gob.pe
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spelling Publicationrp00647600rp06748600rp06746600rp06747600Bazo-Alvarez J.C.Morris T.P.Carpenter J.R.Petersen I.2024-05-30T23:13:38Z2024-05-30T23:13:38Z2021https://hdl.handle.net/20.500.12390/2988https://doi.org/10.2147/CLEP.S3140202-s2.0-85111702945This study was funded by the National Institute for Health Research (NIHR) School for Primary Care Research, project number 444. JCB was sponsored by FONDECYT- CONCYTEC (grant contract number 231-2015- FONDECYT). TPM, TMP and JRC were supported by the Medical Research Council (grant numbers MC_UU_12023/ 21 and MC_UU_12023/29). The study sponsors only had a funding role in this research. Thus, the researchers worked with total independence from their sponsors.Objective: Missing data can produce biased estimates in interrupted time series (ITS) analyses. We reviewed recent ITS investigations on health topics for determining 1) the data management strategies and statistical analysis performed, 2) how often missing data were considered and, if so, how they were evaluated, reported and handled. Study Design and Setting: This was a scoping review following standard recommendations from the PRISMA Extension for Scoping Reviews. We included a random sample of all ITS studies that assessed any intervention relevant to health care (eg, policies or programmes) with individual-level data, published in 2019, with abstracts indexed on MEDLINE. Results: From 732 studies identified, we finally reviewed 60. Reporting of missing data was rare. Data aggregation, statistical tools for modelling population-level data and complete case analyses were preferred, but these can lead to bias when data are missing at random. Seasonality and other time-dependent confounders were rarely accounted for and, when they were, missing data implications were typically ignored. Very few studies reflected on the consequences of missing data. Conclusion: Handling and reporting of missing data in recent ITS studies performed for health research have many shortcomings compared with best practice. © 2021 Bazo-Alvarez et al.Fondo Nacional de Desarrollo Científico y Tecnológico - FondecytengDove Medical Press LtdClinical Epidemiologyinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/4.0/Segmented regressionInterrupted time series analysis-1Missing data-1Multiple imputation-1Scoping review-1https://purl.org/pe-repo/ocde/ford#2.02.04-1Current practices in missing data handling for interrupted time series studies performed on individual-level data: A scoping review in health researchinfo:eu-repo/semantics/reviewreponame:CONCYTEC-Institucionalinstname:Consejo Nacional de Ciencia Tecnología e Innovacióninstacron:CONCYTEC#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#20.500.12390/2988oai:repositorio.concytec.gob.pe:20.500.12390/29882024-05-30 15:26:11.323https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_14cbinfo:eu-repo/semantics/closedAccessmetadata only accesshttps://repositorio.concytec.gob.peRepositorio Institucional CONCYTECrepositorio@concytec.gob.pe#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="624984ce-2233-4d95-b941-0d19bb8775f1"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Current practices in missing data handling for interrupted time series studies performed on individual-level data: A scoping review in health research</Title> <PublishedIn> <Publication> <Title>Clinical Epidemiology</Title> </Publication> </PublishedIn> <PublicationDate>2021</PublicationDate> <DOI>https://doi.org/10.2147/CLEP.S314020</DOI> <SCP-Number>2-s2.0-85111702945</SCP-Number> <Authors> <Author> <DisplayName>Bazo-Alvarez J.C.</DisplayName> <Person id="rp00647" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Morris T.P.</DisplayName> <Person id="rp06748" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Carpenter J.R.</DisplayName> <Person id="rp06746" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Petersen I.</DisplayName> <Person id="rp06747" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Dove Medical Press Ltd</DisplayName> <OrgUnit /> </Publisher> </Publishers> <License>https://creativecommons.org/licenses/by/4.0/</License> <Keyword>Segmented regression</Keyword> <Keyword>Interrupted time series analysis</Keyword> <Keyword>Missing data</Keyword> <Keyword>Multiple imputation</Keyword> <Keyword>Scoping review</Keyword> <Abstract>Objective: Missing data can produce biased estimates in interrupted time series (ITS) analyses. We reviewed recent ITS investigations on health topics for determining 1) the data management strategies and statistical analysis performed, 2) how often missing data were considered and, if so, how they were evaluated, reported and handled. Study Design and Setting: This was a scoping review following standard recommendations from the PRISMA Extension for Scoping Reviews. We included a random sample of all ITS studies that assessed any intervention relevant to health care (eg, policies or programmes) with individual-level data, published in 2019, with abstracts indexed on MEDLINE. Results: From 732 studies identified, we finally reviewed 60. Reporting of missing data was rare. Data aggregation, statistical tools for modelling population-level data and complete case analyses were preferred, but these can lead to bias when data are missing at random. Seasonality and other time-dependent confounders were rarely accounted for and, when they were, missing data implications were typically ignored. Very few studies reflected on the consequences of missing data. Conclusion: Handling and reporting of missing data in recent ITS studies performed for health research have many shortcomings compared with best practice. © 2021 Bazo-Alvarez et al.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication> -1
score 13.904966
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