Severity prognostic factors in patients with acute pancreatitis in Hospital Nacional Sergio E. Bernales

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Objective: To determine the prognostic factors of severity in patients with acute pancreatitis (AP) at the Hospital Nacional Sergio E. Bernales during the period June 2016 to June 2018. Methods: Study of cases and controls, being the cases patients with AP moderately severe or severe and co...

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Detalles Bibliográficos
Autores: Jamanca-Milian, Hellen, Cano-Cardenas, Luis
Formato: artículo
Fecha de Publicación:2019
Institución:Universidad Ricardo Palma
Repositorio:Revista URP - Revista de la Facultad de Medicina Humana
Lenguaje:español
inglés
OAI Identifier:oai:oai.revistas.urp.edu.pe:article/2543
Enlace del recurso:http://revistas.urp.edu.pe/index.php/RFMH/article/view/2543
Nivel de acceso:acceso abierto
Materia:Pancreatitis
APACHE
Prognosis
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spelling Severity prognostic factors in patients with acute pancreatitis in Hospital Nacional Sergio E. BernalesFactores pronósticos de severidad en pacientes con pancreatitis aguda en el servicio de gastroenterología del Hospital Nacional Sergio E. BernalesJamanca-Milian, HellenCano-Cardenas, LuisPancreatitisAPACHEPrognosisObjective: To determine the prognostic factors of severity in patients with acute pancreatitis (AP) at the Hospital Nacional Sergio E. Bernales during the period June 2016 to June 2018. Methods: Study of cases and controls, being the cases patients with AP moderately severe or severe and controls those of mild AP. The medical records were reviewed to apply the APACHE-II score. Chi- square was used and the ORs were obtained with their respective 95% CI. SPSS 25 program was used. Results: 162 medical records were reviewed. 54 (33.3%) patients developed AP moderately severe or severe and 108 (66.7%) had mild AP. Of the patients with AP moderately severe or severe, 55.6% were men; while in mild AP the female sex was predominant with 91.7%. The majority were of biliary origin (83.3%). There was a predominance of mild AP. AP moderately severe or severe was associated with being over 60 years old (OR: 3.10; 95% CI: 1.26-7.65; p= 0.011), presenting pleural effusion (OR: 7.78 95% CI: 5.745-54.418 ; p <0.001), hematocrit>40% (OR: 4.17; 95% CI: 2.07-8.39; p <0.001) and APACHE score ≥8 (OR: 7.88; 95% CI: 3.77-16.45; p<0.001). Conclusions: The factors associated with the severity of pancreatitis were age, presenting pleural effusion, hematocrit> 40% and APACHE score ≥8.Objetivo: Determinar los factores pronósticos de severidad en pacientes con pancreatitis aguda (PA) en el Hospital Nacional Sergio E. Bernales durante el periodo junio 2016 a junio 2018. Metodología: Estudio de casos y controles, siendo los casos los pacientes con pancreatitis moderada o severa y los controles los de pancreatitis leve. Los datos para las variables evaluadas fueron obtenidos a partir de la revisión de Historias Clínicas. Se usó chi-cuadrado para evaluar la asociación y se hallaron los OR con sus respectivos IC 95%. Se utilizó programa SPSS 25. Resultados: Se revisaron 162 historias clínicas de los cuales 54 (33,3%) pacientes desarrollaron PA moderadamente severa (PAMS) o severa (PAS) y 108 (66.7%) cursaron con PA leve (PAL). De las PAMS y PAS 55,6% fueron hombres; mientras que en las PA leves el sexo femenino fue el predominante con un 91,7 %. La mayoría fue de origen biliar con un 83,3%. Los factores asociados a PAMS/PAS incluyeron tener más de 60 años (OR: 3.10; IC 95%: 1,26-7,65; p= 0.011), presentar derrame pleural (OR: 7,78 IC 95%: 5,745-54,418; p<0.001), hematocrito >40% (OR: 4,17; IC 95%: 2.07-8.39; valor p: <0.001) y puntuación APACHE ≥8 (OR: 7,88; IC 95%: 3.77-16.45; p<0,001). Conclusiones: Los factores asociados a severidad de la pancreatitis fueron la edad, presentar derrame pleural, hematocrito >40% y puntuación APACHE ≥8.Universidad Ricardo Palma2019-12-26info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdftext/htmltext/htmlhttp://revistas.urp.edu.pe/index.php/RFMH/article/view/254310.25176/RFMH.v20i1.2543Revista de la Facultad de Medicina Humana; Vol 20 No 1 (2020): Revista de la Facultad de Medicina Humana; 1Revista de la Facultad de Medicina Humana; Vol. 20 Núm. 1 (2020): Revista de la Facultad de Medicina Humana; 12308-05311814-5469reponame:Revista URP - Revista de la Facultad de Medicina Humanainstname:Universidad Ricardo Palmainstacron:URPspaenghttp://revistas.urp.edu.pe/index.php/RFMH/article/view/2543/2738http://revistas.urp.edu.pe/index.php/RFMH/article/view/2543/2739http://revistas.urp.edu.pe/index.php/RFMH/article/view/2543/2740http://revistas.urp.edu.pe/index.php/RFMH/article/view/2543/2741info:eu-repo/semantics/openAccess2021-06-02T16:10:20Zmail@mail.com -
dc.title.none.fl_str_mv Severity prognostic factors in patients with acute pancreatitis in Hospital Nacional Sergio E. Bernales
Factores pronósticos de severidad en pacientes con pancreatitis aguda en el servicio de gastroenterología del Hospital Nacional Sergio E. Bernales
title Severity prognostic factors in patients with acute pancreatitis in Hospital Nacional Sergio E. Bernales
spellingShingle Severity prognostic factors in patients with acute pancreatitis in Hospital Nacional Sergio E. Bernales
Jamanca-Milian, Hellen
Pancreatitis
APACHE
Prognosis
title_short Severity prognostic factors in patients with acute pancreatitis in Hospital Nacional Sergio E. Bernales
title_full Severity prognostic factors in patients with acute pancreatitis in Hospital Nacional Sergio E. Bernales
title_fullStr Severity prognostic factors in patients with acute pancreatitis in Hospital Nacional Sergio E. Bernales
title_full_unstemmed Severity prognostic factors in patients with acute pancreatitis in Hospital Nacional Sergio E. Bernales
title_sort Severity prognostic factors in patients with acute pancreatitis in Hospital Nacional Sergio E. Bernales
dc.creator.none.fl_str_mv Jamanca-Milian, Hellen
Cano-Cardenas, Luis
author Jamanca-Milian, Hellen
author_facet Jamanca-Milian, Hellen
Cano-Cardenas, Luis
author_role author
author2 Cano-Cardenas, Luis
author2_role author
dc.subject.none.fl_str_mv Pancreatitis
APACHE
Prognosis
topic Pancreatitis
APACHE
Prognosis
dc.description.none.fl_txt_mv Objective: To determine the prognostic factors of severity in patients with acute pancreatitis (AP) at the Hospital Nacional Sergio E. Bernales during the period June 2016 to June 2018. Methods: Study of cases and controls, being the cases patients with AP moderately severe or severe and controls those of mild AP. The medical records were reviewed to apply the APACHE-II score. Chi- square was used and the ORs were obtained with their respective 95% CI. SPSS 25 program was used. Results: 162 medical records were reviewed. 54 (33.3%) patients developed AP moderately severe or severe and 108 (66.7%) had mild AP. Of the patients with AP moderately severe or severe, 55.6% were men; while in mild AP the female sex was predominant with 91.7%. The majority were of biliary origin (83.3%). There was a predominance of mild AP. AP moderately severe or severe was associated with being over 60 years old (OR: 3.10; 95% CI: 1.26-7.65; p= 0.011), presenting pleural effusion (OR: 7.78 95% CI: 5.745-54.418 ; p <0.001), hematocrit>40% (OR: 4.17; 95% CI: 2.07-8.39; p <0.001) and APACHE score ≥8 (OR: 7.88; 95% CI: 3.77-16.45; p<0.001). Conclusions: The factors associated with the severity of pancreatitis were age, presenting pleural effusion, hematocrit> 40% and APACHE score ≥8.
Objetivo: Determinar los factores pronósticos de severidad en pacientes con pancreatitis aguda (PA) en el Hospital Nacional Sergio E. Bernales durante el periodo junio 2016 a junio 2018. Metodología: Estudio de casos y controles, siendo los casos los pacientes con pancreatitis moderada o severa y los controles los de pancreatitis leve. Los datos para las variables evaluadas fueron obtenidos a partir de la revisión de Historias Clínicas. Se usó chi-cuadrado para evaluar la asociación y se hallaron los OR con sus respectivos IC 95%. Se utilizó programa SPSS 25. Resultados: Se revisaron 162 historias clínicas de los cuales 54 (33,3%) pacientes desarrollaron PA moderadamente severa (PAMS) o severa (PAS) y 108 (66.7%) cursaron con PA leve (PAL). De las PAMS y PAS 55,6% fueron hombres; mientras que en las PA leves el sexo femenino fue el predominante con un 91,7 %. La mayoría fue de origen biliar con un 83,3%. Los factores asociados a PAMS/PAS incluyeron tener más de 60 años (OR: 3.10; IC 95%: 1,26-7,65; p= 0.011), presentar derrame pleural (OR: 7,78 IC 95%: 5,745-54,418; p<0.001), hematocrito >40% (OR: 4,17; IC 95%: 2.07-8.39; valor p: <0.001) y puntuación APACHE ≥8 (OR: 7,88; IC 95%: 3.77-16.45; p<0,001). Conclusiones: Los factores asociados a severidad de la pancreatitis fueron la edad, presentar derrame pleural, hematocrito >40% y puntuación APACHE ≥8.
description Objective: To determine the prognostic factors of severity in patients with acute pancreatitis (AP) at the Hospital Nacional Sergio E. Bernales during the period June 2016 to June 2018. Methods: Study of cases and controls, being the cases patients with AP moderately severe or severe and controls those of mild AP. The medical records were reviewed to apply the APACHE-II score. Chi- square was used and the ORs were obtained with their respective 95% CI. SPSS 25 program was used. Results: 162 medical records were reviewed. 54 (33.3%) patients developed AP moderately severe or severe and 108 (66.7%) had mild AP. Of the patients with AP moderately severe or severe, 55.6% were men; while in mild AP the female sex was predominant with 91.7%. The majority were of biliary origin (83.3%). There was a predominance of mild AP. AP moderately severe or severe was associated with being over 60 years old (OR: 3.10; 95% CI: 1.26-7.65; p= 0.011), presenting pleural effusion (OR: 7.78 95% CI: 5.745-54.418 ; p <0.001), hematocrit>40% (OR: 4.17; 95% CI: 2.07-8.39; p <0.001) and APACHE score ≥8 (OR: 7.88; 95% CI: 3.77-16.45; p<0.001). Conclusions: The factors associated with the severity of pancreatitis were age, presenting pleural effusion, hematocrit> 40% and APACHE score ≥8.
publishDate 2019
dc.date.none.fl_str_mv 2019-12-26
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dc.publisher.none.fl_str_mv Universidad Ricardo Palma
publisher.none.fl_str_mv Universidad Ricardo Palma
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Revista de la Facultad de Medicina Humana; Vol. 20 Núm. 1 (2020): Revista de la Facultad de Medicina Humana; 1
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