Biochemistry of maternal and umbilical cord blood in Cerro de Pasco (4,200 m.)

• Autores: Guerra García, Roger, Lozano Ríos, Rodolfo, Cateriano, Miguel
• Formato: artículo
• Fecha de Publicación: 2015
• Institución: Sociedad Peruana de Obstetricia y Ginecología
• Repositorio: Revista SPOG - Revista Peruana de Ginecología y Obstetricia
• Lenguaje: español
• OAI Identifier: oai:ojs.spog:article/801
• Enlace del recurso: http://www.spog.org.pe/web/revista/index.php/RPGO/article/view/801
• Nivel de acceso: acceso abierto

The authors have studied several blochemical parameters in maternal and cord blood from 18 normal deliveries ocurred in Cerro de Pasco, at an altitude of 14000 ft.; as control 16 cases attended at the Maternity Hospital in Lima (445 ft.9 were studied. Newborn weights were similar: 3205 ± 343 g in C. P. and 3086 ± 495 g in Lima; Apgar score was also similar 8.4 and 8.2  respectively. In cord blood mean values in C. P. were: Hematocril 52.5 % ± 6.5 %; pottassium 6.0 ± 0.9, sodium 146 ± 9.3, chloride 110 ± 7.7 m.Eq ./L creatinine 1.14 ± 0 .3, glycemia 67 ± 19 and urea 32.2 ± 12.9 mg.%. Same determinations in Lima were: Hematocrit 48.8 % ± 4.5, similar to  C. P. (p > 0.05]; pottassium 5.0 ± 0.4, sodium 136 ± 2.2 and chloride 103 ± 2.6 m.Eq ./L; the electrolite valves were lower in Lima with p values of > 0.006, < 0.02 and < 0.001 respectively. Creatinine was 0.84 ± 0.3 mg.% lower than C. P. (p < 0.02); glycemia was 72 ± 13 and urea 33.8 ± 4.7 both values similar to those registered in C. P. (p > 0.4 and > 0 .5). In maternal blood mean values were as follows: In C. P. hematocrit 45 % ± 3; pottassium 4.6 % ± 1.1, sodium 138 ± 7.1, chloride 103 ± 5.7 m.Eq./L; creatinine 1.04 ± 0.1, glycemia 76.4 ± 13.9 and urea 30.0 ± 13.2 mg.%. Some determinations in Lima were: Hematocril 38% ± 4.6 significantly lower than C. P. (p 0.001) pottasium 4.5 ± 0.7, sodium 136 ± 12.9 and chloride 102 ± 5.3, values similar to C. P. Creatinine was 0.81 ± 0.2 lower than C. P. (p < 0.02) but glycemia and urea had higher concentration: 87 ± 6.2 and 43.5 ± 5 mg. with p values < 0.05 and 0.002 respectively. It is concluded that newborns at high altitude present several biochemical characteristics that could be related to the doubled neonatal mortality observed in the Andean region.