We report the study on the synthesis of indium-doped cobalt ludwigite (Co2InBO5). The Match program, applied to the XRD powder standard, determined that the compound consists of two phases: phase I, ludwigite Co2InBO5 and phase II, the indium oxide In2O3 impurity. The Rietveld refinement applied to the XRD powder standard determined that the percentage by weight of phase I was 98.18% and the percentage by weight of phase II was 1.82%. The atomic ratio between Co and in corresponded to Co/In=2/1, for a goodness of fit s = 1.64 and Chi2 ≅ 2.70. With these adjustment values, the chemical content of the experimental compound was adjusted to its theoretical chemical stoichiometric content. In the unit cell, the different types of atoms occupied the Wyckoff positions 2b, 2c, 4g, and 4h. Atoms of the same or different types can occupy the same Wyckoff position, but a group of them occupy equi...