The present study entitled "Analysis and evaluation of the application of the general treasury regulations in the management of funds of the National University of the Peruvian Amazon 2021" and had as a general objective to analyze the incidence of compliance with the general treasury regulations in the management of public funds at the National University of the Peruvian Amazon, during 2021. The research design was non-experimental, the applied research methods were quantitative, the types of study were descriptive and longitudinal, the methods used were deductive, descriptive, and analytical, the techniques used were direct observation, documentary analysis and questionnaires. Through the application of the questionnaire, an analysis of the seven most important general treasury regulations of the entity was conducted, and it was found that the general treasury regulations 6 - use of a ...