El objetivo de este trabajo fue sintetizar un copolímero de estireno (St) y acrilato de butilo (AB) entrecruzado con metacrilato de alilo mediante polimerización heterogénea semicontinua con el fin de estudiar las propiedades mecánicas de películas poliméricas preparadas a partir de los látex obtenidos. Los látex de copolímero fueron estables y las nanopartículas con morfología esférica se observaron mediante Microscopía Electrónica de Transmisión (TEM). Los látex tuvieron conversiones finales entre 92,5 y 97,0%, las cuales fueron determinadas por el método gravimétrico, y un contenido de sólidos cercano al 20%. Las nanopartículas de látex tenían un diámetro medio de 59,1; 55,1 y 49,0 nm para velocidades de dosificación de monómero de 0,75; 0,45 y 0,15 g / min, respectivamente. Mediante la caracterización mecánica de las películas poliméricas y según el aná...

Septal Neuroblastoma (SN 56) cells are hybrid cells made through cell fusions between quiescent medial septum neurons (cholinergic) and tumoral neuroblastoma cells. Cholinergic cells synthesize and release the neurotransmitter acetylcholine. Preliminary studies in our laboratory revealed that SN 56 neurons also express the vesicular glutamate transporter type 1 (VGluT1), a protein that is normally produced by glutamatergic neurons. This discovery prompted us to hypothesize that SN 56 neurons may also co-express a glutamatergic phenotype which is important because glutamatergic neurons have been associated to the pathogenesis of neurological disorders such as Alzheimer’s disease. To assess whether SN 56 neurons express in fact both phenotypes, we conducted experiments in differentiated and no differentiated SN 56 cell, to confirm the expression of glutamatergic phenotype, by qPCR, weste...

Septal Neuroblastoma (SN 56) cells are hybrid cells made through cell fusions between quiescent medial septum neurons (cholinergic) and tumoral neuroblastoma cells. Cholinergic cells synthesize and release the neurotransmitter acetylcholine. Preliminary studies in our laboratory revealed that SN 56 neurons also express the vesicular glutamate transporter type 1 (VGluT1), a protein that is normally produced by glutamatergic neurons. This discovery prompted us to hypothesize that SN 56 neurons may also co-express a glutamatergic phenotype which is important because glutamatergic neurons have been associated to the pathogenesis of neurological disorders such as Alzheimer’s disease. To assess whether SN 56 neurons express in fact both phenotypes, we conducted experiments in differentiated and no differentiated SN 56 cell, to confirm the expression of glutamatergic phenotype, by qPCR, weste...