Objective: Identify the relationship between physical, psychological, sexual or abandonment violence against women (the mother) inflicted by an intimate partner and the mental health that their adolescent child may suffer in Peru. Methods: Analysis of a subset of the sample of the database of epidemiological studies in mental health conducted from 2003 to 2012 by the National Institute of Mental Health “Honorio Delgado-Hideyo Noguchi” (bases corresponding to married women and their adolescent children were used, matching the data of both populations). Bivariate and multivariate analysis were performed, using the complex samples option and the use of expansion factors according to the sample design of the study. Results: Adolescents whose mothers had been victims of violence by their partner had lower scores on the scales of quality of life, personal satisfaction, self-esteem, satisfa...

About one-third of patients with major depressive disorder do not respond to antidepressant therapy, resulting in a condition known as treatment-resistant depression (TRD). The objective of this review is to evaluate the available evidence on the effectiveness and/or efficacy of the drug esketamine as a therapy in cases of TRD, with a primary focus on the sociodemographic and methodological characteristics of the available studies. An exploratory systematic review of the topic was conducted using the key terms “esketamine” and “treatment-resistant depression.” Clinical trials that included efficacy and/or effectiveness outcomes were selected. Sociodemographic information, characteristics of the clinical trials and interventions, results, and individual risk of bias were collected. Thirteen clinical trials were included. Ten different definitions for TRD and three for remission we...