Introduction: Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, which mainly affects the lungs, although it can compromise other organs. Its multidrug-resistant (MDR) form, characterized by resistance to isoniazid and rifampicin, and its extensively drug-resistant (XDR) form, which exhibits additional resistance to fluoroquinolones and second-line drugs, represent a growing threat to public health. These variants make treatment difficult and increase morbidity and mortality, especially in the pediatric population of vulnerable regions such as the Peruvian Amazon, where socioeconomic and geographic factors limit timely access to diagnosis and treatment. Objective: To determine the geographical distribution and factors associated with MDR and XDR tuberculosis in the pediatric population of a hospital in the Peruvian Amazon, 2024-2025. Method: The study was designe...