The concept of Morgagni, the disease lies in a particular organ, Pathology has dominated for many years. In the past century, coordinated the study, clinical and pathological, has revealed that there are diseases that compromise while various organs or tissues from interrelated anatomically and functionally. Arises then, the concept of system and example of these disease are diseases of Endothelial and Hematopoietic Systems reticulum.

Informe IMARPE; n° 62, 1978, 14 p.